2,6-Dimethylheptan-4-on Chemische Eigenschaften,Einsatz,Produktion Methoden
ERSCHEINUNGSBILD
FARBLOSE FLüSSIGKEIT MIT CHARAKTERISTISCHEM GERUCH.
CHEMISCHE GEFAHREN
Reagiert mit Oxidationsmitteln. Greift einige Kunststoffarten an.
ARBEITSPLATZGRENZWERTE
TLV: 25 ppm (als TWA) (ACGIH 2005).
MAK: IIb (nicht festgelegt, aber Informationen vorhanden) (DFG 2005).
AUFNAHMEWEGE
Aufnahme in den Körper durch Inhalation der Dämpfe und durch Verschlucken.
INHALATIONSGEFAHREN
Beim Verdampfen bei 20°C tritt langsam eine gesundheitsschädliche Kontamination der Luft ein.
WIRKUNGEN BEI KURZZEITEXPOSITION
WIRKUNGEN BEI KURZZEITEXPOSITION: Die Substanz reizt die Augen, die Haut und die Atemwege. Exposition gegenüber hohen Konzentrationen kann Bewusstseinstrübung verursachen.
WIRKUNGEN NACH WIEDERHOLTER ODER LANGZEITEXPOSITION
Wiederholter oder andauernder Hautkontakt kann Dermatitis hervorrufen.
LECKAGE
Belüftung. Ausgelaufene Flüssigkeit möglichst in abdichtbaren Behältern sammeln. Reste mit Sand oder inertem Absorptionsmittel aufnehmen und an einen sicheren Ort bringen. Persönliche Schutzausrüstung: Atemschutzgerät, A/P2-Filter für organische Dämpfe und schädlichen Staub.
R-Sätze Betriebsanweisung:
R10:Entzündlich.
R37:Reizt die Atmungsorgane.
S-Sätze Betriebsanweisung:
S24:Berührung mit der Haut vermeiden.
Beschreibung
2, 6-Dimethyl-4-heptanone, also known as diisobutyl ketone, belongs to the family of ketones, being a flavoring ingredient. It can also be used as the extraction solvent for the determination of ten trace metals (V, Cr, Fe, Co, Ni, Cu, Zn, Mo, Cd, Pb) in aqueous samples with plasma atomic emission spectrometry. Similar logic can also be applied to the measurement of phosphorus using 2, 6-dimethyl-4-heptanone as the extraction agent. It is also an important organic solvent widely used as industrial intermediates.
Chemische Eigenschaften
5-Methyl-3-heptanone is a colorless liquid with low solubility in water
(0.3 wt %); water is poorly soluble in the ketone
(0.9 wt %). 5-Methyl-3-heptanone is highly soluble in common organic solvents.
Physikalische Eigenschaften
Clear, colorless liquid with a mild, sweet, ether-like odor. Odor threshold concentration is 0.11
ppm (quoted, Amoore and Hautala, 1983).
Occurrence
Reported found in baked potato and wheaten bread.
Verwenden
2,6-Dimethyl-4-heptanone is used as a coating solvent. It is an active component of mint oil. It acts as a dispersant for organosol type resins. It is involved in the antigerminative treatment of bulbs and tubers. Further, it is used as a solvent for nitrocellulose. In addition to this, it acts as an intermediate in the preparation of inhibitors, active pharmaceutical ingredients and dyes.
Vorbereitung Methode
Diisobutyl ketone is produced by hydrogenation of phorone
or by metal-catalyzed decomposition of isovaleric acid.It is also a by-product in the manufacture of methyl isobutyl
ketone.
Allgemeine Beschreibung
A clear colorless liquid. Flash point 140°F. Less dense than water and insoluble in water. Vapors heavier than air.
Air & Water Reaktionen
Flammable. Insoluble in water.
Reaktivität anzeigen
2,6-Dimethyl-4-heptanone may attack some plastics. 2,6-Dimethyl-4-heptanone reacts with oxidizers.
Health Hazard
Inhalation of vapor causes irritation of nose and throat. Ingestion causes irritation of mouth and stomach. Vaporirritates eyes. Contact with liquid irritates skin.
Chemische Reaktivität
Reactivity with Water No reaction; Reactivity with Common Materials: May attack some forms of plastics; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.
Sicherheitsprofil
Moderately toxic by
ingestion and inhalation. Mddly toxic by skin
contact. Human systemic effects by
inhalation: headache, nausea or vomiting,
and unspecified eye effects. An eye and skin
irritant. Narcotic in high concentrations.
Flammable liquid when exposed to heat or
flame; can react with oxidizing materials. To
fight fire, use Con, dry chemical, water
spray, mist or fog. When heated to
decomposition it emits acrid smoke and
fumes. See also KETONES.
Environmental Fate
Biological. Using the BOD technique to measure biodegradation, the mean 5-d BOD value (mM
BOD/mM diisobutyl ketone) and ThOD were 4.86 and 37.4%, respectively (Vaishnav et al.,
1987).
Chemical/Physical. Diisobutyl ketone will not hydrolyze because it has no hydrolyzable
functional group.
At an influent concentration of 300 mg/L, treatment with GAC resulted in nondetectable
concentrations in the effluent. The adsorbability of the carbon used was 60 mg/g carbon (Guisti et
al., 1974).
Waste disposal
Incineration, molten metal salt destruction.
Einzelnachweise
Bone, K. M., and W. D. Hibbert. "Solvent extraction with ammonium pyrrolidinedithiocarbamate and 2,6-dimethyl-4-heptanone for the determination of trace metals in effluents and natural waters." Analytica Chimica Acta 107.JUN(1979):219-229.
Miyazaki, Akira, A. Kimura, and Y. Umezaki. "Determination of ng ml-1 levels of phosphorus in waters by diisobutyl ketone extraction and inductively coupled plasma atomic emission spectrometry." Analytica Chimica Acta 127.96(1981):93-101.
Zhang, Fagen, et al. "Comparative metabolism and pharmacokinetics of diisobutyl ketone and diisobutyl carbinol in male SD rats." Toxicology Letters 232.1(2015):175-181.
2,6-Dimethylheptan-4-on Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
