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Isoliquiritigenin Produkt Beschreibung

Isoliquiritigenin Struktur
961-29-5
CAS-Nr.
961-29-5
Englisch Name:
Isoliquiritigenin
Synonyma:
ISL;gu17;ISOLIQUIRTIGENIN;Isqliquiritigenin;ISOLIQUIRITIGENIN;ISOLIQUIRITIGENIN(P);ISOLIQUIRITIGENIN(RG);Isoliquiritigenin, >=98%;2',4',4-TRIHYDROXYCHALCONE;4,2',4'-TRIHYDROXYCHALCONE
CBNumber:
CB9131280
Summenformel:
C15H12O4
Molgewicht:
256.25
MOL-Datei:
961-29-5.mol

Isoliquiritigenin Eigenschaften

Schmelzpunkt:
206-210°C
storage temp. 
2-8°C
Löslichkeit
H2O: <0.1 mg/mL
Aggregatzustand
powder
Farbe
yellow to orange
Sensitive 
Light Sensitive & Hygroscopic
BRN 
1914296
CAS Datenbank
961-29-5(CAS DataBase Reference)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
R-Sätze: 36/37/38
S-Sätze: 26-37
WGK Germany  3
RTECS-Nr. FL7080000
HS Code  29145090
Bildanzeige (GHS)
Alarmwort
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizität (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung
Sicherheit
P261 Einatmen von Staub vermeiden.
P304+P340 BEI EINATMEN: Die Person an die frische Luft bringen und für ungehinderte Atmung sorgen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.
P405 Unter Verschluss aufbewahren.

Isoliquiritigenin Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften

Yellow solid

Verwenden

aldose reductase inhibitor, antineoplastic, antiinflammatory

Verwenden

Isoliquiritigenin (ISL) is a flavonoid found in licorice root and several other plants that displays antioxidant, anti-inflammatory, and antitumor activities as well as hepatoprotection against steatosis-induced oxidative stress. ISL induces quinone reduc

Anticancer Research

It is extracted from Dipteryx odorata seeds, found to be active in induction of quininereductase, and thus prevents chemical carcinogenesis. In a dose- and time-dependentmanner, it significantly inhibits the proliferation of prostate cancer cells,and this isoliquiritigenin-induced cell cycle arrest and antiproliferative effects maybe manifested by growth arrest- and DNA damage-inducible gene 153 (GADD153).It induces apoptosis in prostate cancer cells through mitochondrial apoptosispathway in which mitochondrial membrane potential is disrupted, cytochrome-cand Smac/Diablo are released, and caspase-9 is activated. It is reported to enhancethe expression of universal inhibitor of cyclin-dependent kinases, p21CIP1/WAF1, in adose- and time-dependent manner in A549 human lung cancer cells (Kanazawaet al. 2003; Ii et al. 2004; Balunas and Kinghorn 2005; Jung et al. 2006).

Isoliquiritigenin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Isoliquiritigenin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 215)Lieferanten
Firmenname Telefon Fax E-Mail Land Produktkatalog Edge Rate
NanJing Spring & Autumn Biological Engineering CO., LTD.
13815411950
0086-25-83337318 sale03@cqherb.com CHINA 354 58
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 sales@capotchem.com China 19918 60
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3194 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32447 55
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 24191 60
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
Biochempartner
0086-13720134139
candy@biochempartner.com CHINA 969 58
Chengdu Biopurify Phytochemicals Ltd.
18080483897
maggie@biopurify.com CHINA 2258 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23980 58
Hubei xin bonus chemical co. LTD
86-13657291602
027-59338440 sales@guangaobio.com CHINA 23049 58

961-29-5()Verwandte Suche:


  • (2E)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one
  • ISL
  • (E)-1-(2,4-Dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one 2',4,4'-Trihydroxychalcone
  • (E)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one
  • Isoliquiritigenin (E)-1-(2,4-Dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one
  • Isoliquiritigenin, >=98%
  • 4,2',4'-TRIHYDROXYCHALCONE
  • 2',4',4-TRIHYDROXYCHALCONE
  • ISOLIQUIRTIGENIN
  • ISOLIQUIRITIGENIN
  • (e)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one
  • gu17
  • Isqliquiritigenin
  • ISOLIQUIRTEGENIN (2',4,4'-TRIHYDROXYCHAL
  • ISOLIQUIRITIGENIN(P)
  • ISOLIQUIRITIGENIN(RG)
  • (E)-1-(2,4-Dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one, 4,2μ,4μ-Trihydroxychalcone
  • Isoliquiritigenin,4,2',4'-Trihydroxychalcone
  • (E)-2',4,4'-Trihydroxychalcone
  • 2',4,4'-Trihydroxy-trans-chalcone
  • 2’,4,4’-trihydroxy-chalcon
  • 4,4’-trihydroxychalcone(e)-2
  • 4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-1-((e)-2-propen-1-on
  • Isoliquiritigenin 961-29-5
  • 961-29-5
  • BioChemical
  • Cell Biology
  • Cell Signaling and Neuroscience
  • Cyclic Nucleotide Metabolism
  • G Proteins and Cyclic Nucleotides
  • Guanylyl Cyclase Activators
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • Inhibitors
  • Chalcones
  • The group of Liquorice
  • Aromatics
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • sy
  • -
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