CALPAIN INHIBITOR II Chemische Eigenschaften,Einsatz,Produktion Methoden
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
white to off-white powder
Verwenden
Calpain inhibitor II is a cell-permeable peptide that restricts the activity of calpain, cathepsin L and cathepsin B. Calpain inhibitor II also prevents the methylmercury-induced cell death of cultured rat cerebellar neurons.
Allgemeine Beschreibung
A cell-permeable inhibitor of calpain I (K
i = 120 nM), calpain II (K
i = 230 nM), cathepsin B (K
i = 100 nM), and cathepsin L (K
i = 0.6 nM). Inhibits activation-induced programmed cell death and restores defective immune responses in HIV
+ donors. Also prevents nitric oxide produced by activated macrophages by interfering with transcription of the inducible nitric oxide synthase gene.
CALPAIN INHIBITOR II Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
