Natrium-2-[[(3α,5β,12α)-3,12-dihydroxy-24-oxocholan-24-yl]amino]ethan-1-sulfonat
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- CAS-Nr.
- 1180-95-6
- Bezeichnung:
- Natrium-2-[[(3α,5β,12α)-3,12-dihydroxy-24-oxocholan-24-yl]amino]ethan-1-sulfonat
- Englisch Name:
- Taurodeoxycholic acid sodium salt
- Synonyma:
- SODIUM TAURODEOXYCHOLATE;Taurodeoxycholate sodium salt;Taurodeoxycholic acid sodium salt hydrate;5B2;12B1;sodium 2-[[(3B1;sodium taurodeoxylate;SodiuM taurodeoxycholat;Sodium deoxytaurocholate;Taurodeoxycholate sodium
- CBNumber:
- CB9349065
- Summenformel:
- C26H44NNaO6S
- Molgewicht:
- 521.69
- MOL-Datei:
- 1180-95-6.mol
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Natrium-2-[[(3α,5β,12α)-3,12-dihydroxy-24-oxocholan-24-yl]amino]ethan-1-sulfonat Eigenschaften
- Schmelzpunkt:
- 168 °C (dec.)(lit.)
- alpha
- 33 º (c=3, water)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- Löslichkeit
- H2O: 0.5 M at 20 °C, clear, colorless to faintly yellow
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
- Wasserlöslichkeit
- soluble
- InChIKey
- YXHRQQJFKOHLAP-UROAIUCXNA-M
- CAS Datenbank
- 1180-95-6(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
Xi |
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| R-Sätze: |
37 |
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| S-Sätze: |
24/25 |
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| WGK Germany |
3 |
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| F |
3-10 |
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| HS Code |
29242990 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizität (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P302+P352 |
BEI BERÜHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckmäßig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen. |
| P321 |
Besondere Behandlung |
| P332+P313 |
Bei Hautreizung: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen. |
| P362 |
Kontaminierte Kleidung ausziehen und vor erneutem Tragen waschen. |
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Natrium-2-[[(3α,5β,12α)-3,12-dihydroxy-24-oxocholan-24-yl]amino]ethan-1-sulfonat Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R37:Reizt die Atmungsorgane.
Chemische Eigenschaften
white to almost white crystalline powder
Verwenden
Deoxycholyltaurine rescues human colon cancer cells from apoptosis by activating EGFR-dependent PI3K/Akt signaling.
läuterung methode
The Na salt is dissolved in the smallest volume of H2O, a saturated solution of aqueous NaCl/Et2O is added and the mixture is stored at 0o for 24hours. Then shake the mixture well, keep it in the cold for another day and filter the crystals with gentle shaking, wash them with ice-cold saturated aqueous NaCl saturated with Et2O, dry them over CaCl2 and extract them with absolute EtOH. Add ~10mL of H2O to the solid followed by enough Et2O to incipient cloudiness. Store it overnight at 0o. Add ice-cold Et2O to make 250mL, collect the crystals, wash them with Et2O then pet ether and dry them in air. The purification can be repeated with NaCl and Et2O with ~85% recovery. NB: precipitation will not occur unless enough H2O is present. Its solubility in H2O is 10%. [Cortese J Am Chem Soc 59 2532 1937.] The free acid has m 141-144o. [Norman Ark Kemi 8 331 1956.] It forms mixed micelles and solubilises some membrane proteins [Hajjar et al. J Biol Chem 2 5 8 192 1983]. [Beilstein 10 IV 1611.]
Natrium-2-[[(3α,5β,12α)-3,12-dihydroxy-24-oxocholan-24-yl]amino]ethan-1-sulfonat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Natrium-2-[[(3α,5β,12α)-3,12-dihydroxy-24-oxocholan-24-yl]amino]ethan-1-sulfonat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 258)Lieferanten
1180-95-6(Natrium-2-[[(3α,5β,12α)-3,12-dihydroxy-24-oxocholan-24-yl]amino]ethan-1-sulfonat)Verwandte Suche:
- TAURODEOXYCHOLIC ACID SODIUM
- TAURODEOXYCHOLIC ACID SODIUM SALT
- SODIUM TAURODEOXYCHOLATE SODIUM SALT
- SODIUM TAURODESOXYCHOLATE SODIUM SALT
- 2-[(3ALPHA,12ALPHA-DIHYDROXY-24-OXO-5BETA-CHOLAN-24-YL)-AMINO] ETHANESULFONIC ACID SODIUM SALT
- 5BETA-CHOLANIC ACID-3ALPHA,12ALPHA-DIOL 24-N-(2-SULFOETHYL)-AMIDE SODIUM
- 5-BETA-CHOLANIC ACID-3-ALPHA, 12-ALPHA-DIOL N-(2-SULPHOETHYL)-AMIDE SODIUM SALT
- 3ALPHA,12ALPHA-DIHYDROXY-5BETA-CHOLAN-24-OIC ACID N-[2-SULFOETHYL]AMIDE SODIUM SALT
- sodium 2-[[(3alpha,5beta,12alpha)-3,12-dihydroxy-24-oxocholan-24-yl]amino]ethane-1-sulphonate
- Ethanesulfonic acid, 2-(3.alpha.,5.beta.,12.alpha.)-3,12-dihydroxy-24-oxocholan-24-ylamino-, monosodium salt
- sodium taurodeoxylate
- Sodium 2-[[(3a,5b,12a)-3,12-dihydroxy-24-oxocholan-24-yl]amino]ethane-1-sulphonate
- Cholane, ethanesulfonic acid deriv.
- Sodium deoxytaurocholate
- Sodium taurodesoxycholate
- Taurodeoxycholate sodium
- Taurodeoxycholic acid sodium salt hydrate,97%
- 2-[(3α,12α-Dihydroxy-24-oxo-5β-cholan-24-yl)amino]ethanesulfonic acid sodium salt
- 2-[(3α,12α-Dihydroxy-24-oxo-5β-cholane)-24-ylamino]ethanesulfonic acid sodium salt
- 3α,12α-Dihydroxy-24-[[2-(sodiooxysulfonyl)ethyl]amino]-5β-cholane-24-one
- N-(3α,12α-Dihydroxy-24-oxo-5β-cholane-24-yl)taurine sodium salt
- N-[2-(Sodiooxysulfonyl)ethyl]-3α,12α-dihydroxy-5β-cholane-24-oic amide
- Sodium tarurodeoxycholate
- 2-(3α,6α-Dihydroxy-24-oxo-5β-cholan-24-ylamino)ethanesulfonic acid sodium salt
- Sodium Taurodeoxycholic acid
- Taurodeoxycholic acid sodium salt ,97%
- Taurodeoxychloic Acid SodiuM Salt
- SodiuM taurodeoxycholat
- N-(3α,12α-Dihydroxy-5β-cholan-24-oyl)-taurine MonosodiuM Salt
- SodiuM 3α,12α-Dihydroxy-5β-cholanoyltaurate
- SODIUM TAUROUSODEOXYCHOLATE
- Ursodeoxycholic Impurity 16
- sodium 2-[[(3α,5β,12α)-3,12-dihydroxy-24-oxocholan-24-yl]amino]ethane-1-sulphonate
- Ethanesulfonic Acid,2-[[(3A,5B,12A-3,12-Dihydroxy-24-OxocholaN-24-Yl]Amino]-, Monosodium Salt
- Sodium 2-((R)-4-((3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)ethanesulfonate
- Taurodeoxycholic acid sodium saltr
- Taurodeoxycholic acid sodium salt ISO 9001：2015 REACH
- sodium 2-[[(3α,5β,12α)-3,12-dihydroxy-24-oxocholan-24-yl]amino]ethane-1-sulphonate
- Taurodeoxycholicacid (Crude)
- sodium 2-[[(3α,5β,12α)-3,12-dihydroxy-24-o...
- Sodium taurodeoxycholate, hydrate, ≥95% (HPLC)
- )-3,12-dihydroxy-24-oxocholan-24-yl]amino]ethane-1-sulphonate
- 12B1
- 5B2
- sodium 2-[[(3B1
- Sodium Taurodeoxycholate Dried (STDC Dried) extrapure, 97%
- Taurodeoxycholic acid sodium salt hydrate
- SODIUM TAURODEOXYCHOLATE
- Taurodeoxycholate sodium salt
- Urosodeoxycholic Acid Impurity 16
- 5β-CHOLANIC ACID-3α, 12α-DIOL N-(2-SULPHOETHYL)-AMIDE SODIUM SALT
- 1180-95-6
- C26H44NNaO6SxH2O
- C26H44NO6S種a
- Anionic
- BioChemical
- Detergents
- Chiral Reagents
