Cholsure
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- CAS-Nr.
- 81-25-4
- Bezeichnung:
- Cholsure
- Englisch Name:
- Cholic acid
- Synonyma:
- CA;CHOLATE;cholan-24-oic acid;3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid;3A,7A,12A-TRIHYDROXY-5B-CHOLAN-24-OIC ACID;(R)-4-((3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-diMethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid;CHOLALIN;Cholicaci;Cholic acd;CHOLIC ACID
- CBNumber:
- CB9263222
- Summenformel:
- C24H40O5
- Molgewicht:
- 408.58
- MOL-Datei:
- 81-25-4.mol
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Cholsure Eigenschaften
- Schmelzpunkt:
- 200-201 °C (lit.)
- Siedepunkt:
- 449.08°C (rough estimate)
- alpha
- 36 º (c=0.6, 95% EtOH)
- Dichte
- 1.0310 (rough estimate)
- Brechungsindex
- 1.5800 (estimate)
- Flammpunkt:
- 9℃
- storage temp.
- 2-8°C
- Löslichkeit
- methanol: 0.1 g/mL, clear
- pka
- 4.98(at 20℃)
- Farbe
- White to Brown
- Wasserlöslichkeit
- 0.28 g/L (15 ºC)
- Merck
- 14,2203
- BRN
- 2822009
- InChIKey
- BHQCQFFYRZLCQQ-OELDTZBJSA-N
- LogP
- 2.03-2.615 at 20℃
- CAS Datenbank
- 81-25-4(CAS DataBase Reference)
- NIST chemische Informationen
- Cholic acid(81-25-4)
- EPA chemische Informationen
- Cholan-24-oic acid, 3,7,12-trihydroxy-, (3.alpha.,5.beta.,7.alpha.,12.alpha.)- (81-25-4)
Cholsure Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Chemische Eigenschaften
white to light beige crystalline powder
Verwenden
Cholic Acid is an emulsifier that exists as colorless plates or a white
crystalline powder which has a bitter taste with a sweetish aftertaste.
it is slightly soluble in water. it functions as an emulsifying agent in
egg white.
Definition
ChEBI: A bile acid that is 5beta-cholan-24-oic acid bearing three alpha-hydroxy substituents at position 3, 7 and 12.
Allgemeine Beschreibung
This Certified Spiking Solution
? is suitable as a starting material in preparation of linearity standards, calibrators, and controls for use in LC-MS/MS and GC/MS bile acid testing methods. Cholic acid is a primary bile acid that plays an important role in cholesterol homeostasis and intestinal absorption of dietary vitamins and lipids. Levels of cholic acid can serve as markers for inborn and acquired hepatobiliary disorders such as biliary atresia and familial intrahepatic cholestasis as well as inborn errors of bile acid synthesis and sclerosing cholangitis.
läuterung methode
This bile acid crystallises from H2O or wet Et2O (as hydrate) or EtOH (as alcoholate). Dry it under vacuum at 94o. When an alcoholic solution of cholic acid + I2 is added to aqueous KI, it forms a molecular compound (C24H40O5I)4 KI. H2O. The methyl ester is dimorphic with m 155o and 162o and [] D 20 +25o (EtOH). [Anderson et al. Biochem J 67 323 1957, 85 236 1962, Beilstein 10 III 2162, IV 2071.]
Cholsure Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Atificial Cow-bezoar
N-(3-α,7-α,12-α-Trihydroxycholan-24-oyl)glycin
Natrium-N-(3-α,7-α,12-α-trihydroxy-24-oxocholan-24-yl)glycinat
3α,7α-Dihydroxy-12-oxo-5β-cholan-24-sure
Dehydrocholsure
Natrium-N-choloyltaurinat
APOCHOLIC ACID
(3a,5b,6a,12a)-3,6,12-trihydroxy-Cholan-24-oic acid
Cholsure Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 577)Lieferanten
81-25-4(Cholsure)Verwandte Suche:
- CHOLALIN
- CHOLAN-24-OIC ACID, 3,7,12-TRIHYDROXY-, (3,5,7,12)-
- CHOLIC ACID
- 3α,7α,12α-Trihydroxy-5α-cholanic acid,
- Cholic acd
- Cyclosphorine
- CHOLIC ACID FREE ACID
- Cholic Acid, High Purity
- CHOLIC ACID:CHOLAN-24-OICACID, 3,7,12-TRIHYDROXY-, (3,5,7,12)-,
- CholicAcidForBiochemistry
- Cholic acid, 98+%
- Bronchokod-13C3
- S-(CarboxyMethyl)-L-cysteine-13C3
- Cholic Acid (CA)
- Cholic acid SynonyMs 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholanic acid
- Cholic acid Vetec(TM) reagent grade, 98%
- (4R)-4-[(8R,9S,10S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
- (4R)-4-[(8R,9S,10S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]valeric acid
- CHOLICACID(FROMOX,BOVINE)
- CHOLICACID(FROMPORCINE,PIG)
- (4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
- 3,7,12-Trihydroxy-cholan-24-oic acid
- 5beta-Cholan-24-oic acid, 3alpha,7alpha,12alpha-trihydroxy-
- Cholan-24-oic acid, 3,7,12-trihydroxy-, (3alpha,5beta,7alpha,12alpha)-
- 3,7,12-TRIHYDROXYCHOLANIC ACID
- 3ALPHA, 7ALPHA, 12ALPHA-TRIHYDROXY-5BETA-CHOLANIC ACID
- 3ALPHA,7ALPHA,12ALPHA-TRIHYDROXY-5BETA-CHOLAN-24-IC ACID
- 3ALPHA,7ALPHA,12ALPHA-TRIHYDROXY-5BETA-CHOLAN-24-OIC ACID
- 7-ALPHA,8-ALPHA,12-ALPHA-TRIHYDROXY-5-BETA-CHOLAN-24-OIC ACID
- 5-BETA-CHOLANIC ACID-3-ALPHA, 7-ALPHA, 12-ALPHA-TRIOL
- CHOLALIC ACID
- CHOLIC ACID(P)
- Isoursocholic acid
- 17b-[1-Methyl-3-carboxypropyl]etiocholane-3a,7a,12a-triol
- 5b-Cholanic acid-3a,7a,12a-triol
- 5b-Cholic acid
- Cholan-24-oic acid, 3,7,12-trihydroxy-, (3a,5b,7a,12a)-
- trihydroxycholanic acid
- 3α,7α,12α-Trihydroxy-5β-cholanic acid, Cholanic acid
- Cholicacid，Cholan-24-oic acid
- 17β-(1-methyl-3-carboxy-propyl)etiocholane-3α，7α，12α-triol
- Cholic acid,97%
- Cholic acid,3α,7α,12α-Trihydroxy-5β-cholanic acid, Cholanic acid
- Cholic Acid (AS)
- (3α,5β,7α12α)-3,7,12-Trihydroxy-cholan-24-oic Acid
- (2R)-2-AMino-3-[(carboxyMethyl)thio]propionic Acid-13C3
- (L)-2-AMino-3-(carboxyMethylthio)propionic Acid-13C3
- (R)-S-(CarboxyMethyl)cysteine-13C3
- 3-[(CarboxyMethyl)thio]-L-alanine-13C3
- AHR 3053-13C3
- Cholic Acid (2 g)
- Cholic
- Cholic acid, 97% 100GR
- Cholic acid, 97% 25GR
- cholic acid powder
- Ursodeoxycholic Acid EP Impurity B(Cholic Acid)
- Cholan-24-oicacid, 3,7,12-trihydroxy
- Ursodeoxycholic Acid Impurity 2（Ursodeoxycholic Acid EP Impurity B）
