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8-Bromotheophylline

8-Bromotheophylline structure

CAS No.: 10381-75-6

Chemical Name:: 8-Bromotheophylline

Synonyms: Nsc164940;AKOS NCG-0005;bromotheophylline;8-Bromotheophyline;8-BROMOTHEOPHYLLINE;LABOTEST-BB LT00134545;Theophylline, 8-bromo-;8-BROMOTHEOPHYLLINE 97%;8-Bromotheophylline >8-Bromotheophylline ,97%

CBNumber:: CB0105862

Molecular Formula:: C7H7BrN4O2

Molecular Weight:: 259.06

MDL Number:: MFCD00022664

MOL File:: 10381-75-6.mol

MSDS File:: SDS

Last updated:2023-09-20 16:43:00

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8-Bromotheophylline Properties

Melting point	295-297°C
Boiling point	469.5±55.0 °C(Predicted)
Density	1.862±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	DMSO (Slightly), Methanol (Slightly, Heated)
pka	pKa 5.45±0.1(H2O t=24) (Uncertain)
form	Solid
color	White to Off-White
BRN	203069
CAS DataBase Reference	10381-75-6
FDA UNII	FZG87K1MQ6
EPA Substance Registry System	1H-Purine-2,6-dione, 8-bromo-3,7-dihydro-1,3-dimethyl- (10381-75-6)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P264-P270-P271-P280-P301+P312+P330-P302+P352-P304+P340+P312-P305+P351+P338-P332+P313-P337+P313-P362-P403+P233-P405-P501
Risk Statements	20/21/22
Safety Statements	24/25-36/37
RIDADR	2811
HazardClass	6.1(b)
PackingGroup	III
HS Code	29395900

8-Bromotheophylline price More Price(31)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	S168378	8-BROMO-1,3-DIMETHYL-3,7-DIHYDRO-PURINE-2,6-DIONE Aldrich	10381-75-6	50mg	$110	2024-03-01	Buy
Sigma-Aldrich	1077708	8-BROMO-1,3-DIMETHYL-3,7-DIHYDRO-PURINE-2,6-DIONE	10381-75-6	400mg	$1310	2024-03-01	Buy
TCI Chemical	B3456	8-Bromotheophylline >98.0%(HPLC)(T)	10381-75-6	1g	$148	2024-03-01	Buy
TCI Chemical	B3456	8-Bromotheophylline >98.0%(HPLC)(T)	10381-75-6	5g	$509	2024-03-01	Buy
TRC	B688150	8-Bromotheophylline	10381-75-6	10g	$690	2021-12-16	Buy

Product number	Packaging	Price	Buy
S168378	50mg	$110	Buy
1077708	400mg	$1310	Buy
B3456	1g	$148	Buy
B3456	5g	$509	Buy
B688150	10g	$690	Buy

8-Bromotheophylline Chemical Properties,Uses,Production

Description

Bromotheophylline is the active moiety of pamabrom, a mixture of 2-amino-2-methyl-propanol and bromotheophylline. From this mixture, bromotheophylline acts as a weak diuretic that has been used along with some analgesics to relieve the symptoms of premenstrual syndrome. Bromotheophylline is categorized on the FDA as a drug substance with an inactive state since March, 1980. It is also approved by Health Canada to be used alone or in combination with [DB00316] in OTC products.

Chemical Properties

White Crystalline Powder

Uses

The active component in the diuretic Diurex.

Purification Methods

It is purified by dissolving in the minimum volume of dilute NaOH (charcoal), filtering and acidifying to pH ca 3.5-4. The solid that separates is collected, dried in vacuo at 100o and stored in a dark container. It has also been recrystallised from EtOH or AcOH. [Blitz & Beck J Prakt Chem [2] 118 158 1928, Fischer & Ach Chem Ber 28 3142 1895, Beilstein 26 H 476, 26 II 227, 26 III/IV 2447.]

8-Bromotheophylline Preparation Products And Raw materials

Raw materials

Acetic anhydride Theophylline Hydrogen bromide Nitric acid

Preparation Products

8-BROMO-7-(2,3-DIHYDROXYPROPYL)-1,3-DIMETHYL-2,3,6,7-TETRAHYDRO-1H-2,6-PURINEDIONE Purino[8,7-b]quinazoline-2,4,6(1H,3H,11H)-trione, 1,3-dimethyl- (9CI) 8-anilino-1,3-dimethyl-7H-purine-2,6-dione 8-BROMO-7-(3-CHLOROPROPYL)-1,3-DIMETHYL-2,3,6,7-TETRAHYDRO-1H-PURINE-2,6-DIONE

8-Bromotheophylline Suppliers

Global( 127)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10828	58
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
Dayang Chem (Hangzhou) Co.,Ltd.	571-88938639 +8617705817739	info@dycnchem.com	CHINA	52867	58
Labnetwork lnc.	+86-27-50766799 +8618062016861	contact@labnetwork.com	China	19994	58
LEAP CHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	24738	58
Coresyn Pharmatech Co., Ltd.	+86-571-86626709 +86-18157142896	cbc@coresyn.com	China	9991	58
Golden Pharma Co., Limited	+undefined18958062155	sales@zjgoldpharm.com	China	5905	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Chongqing Chemdad Co., Ltd	58
Wuhan Chemwish Technology Co., Ltd	58
career henan chemical co	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Labnetwork lnc.	58
LEAP CHEM CO., LTD.	58
Coresyn Pharmatech Co., Ltd.	58
Golden Pharma Co., Limited	58
TargetMol Chemicals Inc.	58

View Lastest Price from 8-Bromotheophylline manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2021-07-02	8-Bromotheophylline 10381-75-6	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd
	2020-01-22	8-BROMOTHEOPHYLLINE 10381-75-6	US $1.00 / KG	1KG	98%HPLC	10tons	Career Henan Chemical Co

8-Bromotheophylline
10381-75-6
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

8-BROMOTHEOPHYLLINE
10381-75-6
US $1.00 / KG
98%HPLC
Career Henan Chemical Co

8-Bromotheophylline Spectrum

8-Bromotheophylline(10381-75-6)¹HNMR

10381-75-6(8-Bromotheophylline)Related Search:

8-Bromotheophylline 8-BROMOXANTHINE 8-BROMO-7-ETHYL-1,3-DIMETHYL-2,3,6,7-TETRAHYDRO-1H-PURINE-2,6-DIONE 8-BROMO-7-(3-CHLOROPROPYL)-1,3-DIMETHYL-2,3,6,7-TETRAHYDRO-1H-PURINE-2,6-DIONE 8-BROMO-7-(2-BROMOPROPYL)-1,3-DIMETHYL-2,3,6,7-TETRAHYDRO-1H-PURINE-2,6-DIONE

ETHYL 2-(8-BROMO-1,3-DIMETHYL-2,6-DIOXO-2,3,6,7-TETRAHYDRO-1H-PURIN-7-YL)ACETATE 8-BROMO-1,3-DIMETHYL-7-(2-OXO-2-PHENYLETHYL)-2,3,6,7-TETRAHYDRO-1H-PURINE-2,6-DIONE 8-BROMO-7-(3-CHLORO-2-HYDROXYPROPYL)-1,3-DIMETHYL-2,3,6,7-TETRAHYDRO-1H-PURINE-2,6-DIONE 8-BROMO-7-(2-HYDROXYPROPYL)-1,3-DIMETHYL-2,3,6,7-TETRAHYDRO-1H-PURINE-2,6-DIONE AKOS BC-1749

ETHYL 4-(8-BROMO-1,3-DIMETHYL-2,6-DIOXO-2,3,6,7-TETRAHYDRO-1H-PURIN-7-YL)BUTANOATE 8-BROMO-1,3,7-TRIMETHYL-3,7-DIHYDRO-PURINE-2,6-DIONE 8-BROMO-1,3-DIMETHYL-7-(2-OXOPROPYL)-2,3,6,7-TETRAHYDRO-1H-PURINE-2,6-DIONE 8-BROMO-7-(2-BROMOBUTYL)-1,3-DIMETHYL-2,3,6,7-TETRAHYDRO-1H-PURINE-2,6-DIONE 8-BROMO-1,3-DIMETHYL-7-PHENETHYL-2,3,6,7-TETRAHYDRO-1H-PURINE-2,6-DIONE

8-BROMO-7-(2-CHLOROBUTYL)-1,3-DIMETHYL-2,3,6,7-TETRAHYDRO-1H-PURINE-2,6-DIONE 8-BROMO-7-(2-CHLOROPROPYL)-1,3-DIMETHYL-2,3,6,7-TETRAHYDRO-1H-PURINE-2,6-DIONE 8-BROMO-7-(2-HYDROXYBUTYL)-1,3-DIMETHYL-2,3,6,7-TETRAHYDRO-1H-PURINE-2,6-DIONE

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8-bromo-3,7-dihydro-1,3-dimethyl-1h-purine-6-dione AKOS NCG-0005 8-BROMOTHEOPHYLLINE 8-BROMO-3,7-DIHYDRO-1,3-DIMETHYL-1H-PURINE-2,6-DIONE 8-BROMO-1,3-DIMETHYL-3,7-DIHYDRO-PURINE-2,6-DIONE LABOTEST-BB LT00134545 8-BROMOTHEOPHYLLINE 97% 1,3-Dimethyl-8-bromoxanthine bromotheophylline 8-Bromotheophylline ,97% 1H-Purine-2,6-dione, 8-bromo-3,7-dihydro-1,3-dimethyl- 8-Bromotheophyline Nsc164940 Theophylline, 8-bromo- 8-bromo-1,3-dimethyl-3,9-dihydro-1H-purine-2,6-dione(SALTDATA: FREE) 8-Bromotheophylline (400 mg) 8-BroMo-1,3-diMethyl-1H-purine-2,6(3H,9H)-dione 8-broMo-1,3-diMethyl-1H-purine-2,6(3H,7H)-dione 8-Bromo-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione 8-bromo-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione 8-Bromotheophylline, ≥98% 8-Bromotheophylline > 1H-Purine-2,6-dione, 8-bromo-3,9-dihydro-1,3-dimethyl- 8-Bromotheophylline (1077708) 10381-75-6 C7H7BrN4O2 Pharmaceutical Raw Materials Nucleotides and Nucleosides Bases & Related Reagents Nucleotides