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Exendin-3 (9-39) amide

CAS No.
133514-43-9
Chemical Name:
Exendin-3 (9-39) amide
Synonyms
EXENDIN (9-39);EXENDIN 3 (9-39);Exendin-4 (9-39);Hexanal Impurity 5;EXENDIN (9-39) AMIDE;EXENDIN FRAGMENT 9-39;EXENDIN-3 (9-39) AMIDE;EXENDIN [9-39] PEPTIDE;Exendin (9-39) Acetate;Exendin 4 (9-39) amide
CBNumber:
CB0109941
Molecular Formula:
C149H234N40O47S
Molecular Weight:
3369.76
MDL Number:
MFCD02179664
MOL File:
133514-43-9.mol
Last updated:2024-05-22 11:23:49

Exendin-3 (9-39) amide Properties

Density 1.51
RTECS LF2460000
storage temp. Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility H2O : 50 mg/mL (14.84 mM; Need ultrasonic)
form Solid
Water Solubility Soluble in water at 1mg/ml
InChIKey WSEVKKHALHSUMB-UHFFFAOYSA-N
EWG's Food Scores 1
FDA UNII 5313W10MYT
NCI Drug Dictionary exendin 9-39

SAFETY

Risk and Safety Statements

WGK Germany  3

Exendin-3 (9-39) amide price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich E7269 Exendin Fragment 9-39 ≥95% (HPLC) 133514-43-9 0.1mg $404 2024-03-01 Buy
Alfa Aesar J66126 Exendin (9-39) 133514-43-9 0.5mg $285 2023-06-20 Buy
Alfa Aesar J66126 Exendin (9-39) 133514-43-9 1mg $466 2023-06-20 Buy
Cayman Chemical 19890 Exendin-3 (9-39) amide ≥95% 133514-43-9 500μg $152 2024-03-01 Buy
Cayman Chemical 19890 Exendin-3 (9-39) amide ≥95% 133514-43-9 1mg $214 2024-03-01 Buy
Product number Packaging Price Buy
E7269 0.1mg $404 Buy
J66126 0.5mg $285 Buy
J66126 1mg $466 Buy
19890 500μg $152 Buy
19890 1mg $214 Buy

Exendin-3 (9-39) amide Chemical Properties,Uses,Production

Description

Exendin-3 (9-39) amide is a truncated form of the exendin-4 peptide that acts as a potent competitive antagonist for the glucagon-like peptide 1 receptor (GLP-1R; Kd = 1.7 nM in CHL cells transfected with cloned human GLP-1). It inhibits exendin-3-induced increases in cAMP levels in guinea pig pancreas cells (IC50 = 20 nM). Exendin-3 (9-39) amide administration in the hypothalamus (10 and 100 μg, i.c.v.) reverses GLP-1 inhibition of feeding behavior in rats.

Uses

Exendin-3 (9-39) is a potent and selective GLP-1 receptor antagonist.

Uses

Biological probe.

General Description

Exendin Fragment 9-39 is an antagonist of glucagon-like peptide-1 (GLP-1) receptor, and also acts as an inhibitor of glucosedependent insulinotropic polypeptide (GIP)-receptor binding. It also prevents the production of cAMP by GIP. GLP-1, along with GIP, acts as a physiological incretin.

Biochem/physiol Actions

GLP-1 (glucagon-like peptide-1) receptor antagonist. Competitive inhibitor of exendin-3 and exendin-4.

storage

Store at -20°C

Exendin-3 (9-39) amide Preparation Products And Raw materials

Raw materials

Preparation Products

Exendin-3 (9-39) amide Suppliers

Global( 139)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Duling International Trade Co. LTD
+8617333973358 sales01@hbduling.cn China 15619 58
GenicBio Limited
+86-21-37621270 service@genicbio.com CHINA 991 58
Shenzhen Nexconn Pharmatechs Ltd
+86-755-89396905 +86-15013857715 admin@nexconn.com China 10247 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Hebei Guanlang Biotechnology Co., Ltd.
+86-19930503282 alice@crovellbio.com China 8829 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19553 58
Cellmano Biotech Limited
0551-65326643 18156095617 info@cellmano.com China 999 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49391 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 27588 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10523 58

View Lastest Price from Exendin-3 (9-39) amide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Exendin-3 (9-39) amide pictures 2024-05-22 Exendin-3 (9-39) amide
133514-43-9
US $3.50 / kg 1kg 99.5% 10 tons Hebei Duling International Trade Co. LTD
Exendin-3 (9-39) amide pictures 2021-11-13 Exendin-3 (9-39) amide
133514-43-9
US $9.90 / KG 100KG 99% 10 tons Hebei Guanlang Biotechnology Co., Ltd.
Exendin-3 (9-39) amide pictures 2021-11-12 Exendin-3 (9-39) amide
133514-43-9
US $9.90 / KG 100KG 99% 10 tons Hebei Guanlang Biotechnology Co., Ltd.
ASP-LEU-SER-LYS-GLN-MET-GLU-GLU-GLU-ALA-VAL-ARG-LEU-PHE-ILE-GLU-TRP-LEU-LYS-ASN-GLY-GLY-PRO-SER-SER-GLY-ALA-PRO-PRO-PRO-SER-NH2 H-ASP-LEU-SER-LYS-GLN-MET-GLU-GLU-GLU-ALA-VAL-ARG-LEU-PHE-ILE-GLU-TRP-LEU-LYS-ASN-GLY-GLY-PRO-SER-SER-GLY-ALA-PRO-PRO-PRO-SER-NH2 EXENDIN 3 (9-39) EXENDIN-3 (9-39) AMIDE EXENDIN (9-39) EXENDIN (9-39) AMIDE EXENDIN [9-39] PEPTIDE EXENDIN FRAGMENT 9-39 DLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH2 M.W. 3369.79 C149H234N40O47S ASP-LEU-SER-LYS-GLN-MET-GLU-GLU-GLU-ALA-VAL-ARG-LEU-PHE-ILE-GLU-TRP-LEU-LYS-ASN-GLY-GLY-PRO-SER-SER-GLY-ALA-PRO-PRO-PRO-SER-NH2: DLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH2 Exendin 3 (heloderma horridum), 1-de-L-histidine-2-de-L-serine-3-de-L-aspartic acid-4-deglycine-5-de-L-threonine-6-de-L-phenylalanine-7-de-L-threonine-8-de-L-serine- 9-39-Exendin 3(Heloderma horridum) EXENDIN FRAGMENT 9-39;EXENDIN (9-39) H-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2 Exendin FragMent 9-39Exendin H-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2 acetate salt 9-39-Exendin 3(Heloderma horridum) (9CI) Exendin (9-39) Acetate Exendin 4 (9-39) amide Asp-LEU-SER-LYS-GLN-MET-GLU-GLU-GLU-ALA-VAL-ARG-LEU-PHE-ILE-GLU-TRp-LEU-LYS-ASN-GLY-GLY-PRO-SER-SER-GLY-ALA-PRO-PRO-PRO-SER-NH2, ≥95%(HPLC) L-Serinamide, L-α-aspartyl-L-leucyl-L-seryl-L-lysyl-L-glutaminyl-L-methionyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-alanyl-L-valyl-L-arginyl-L-leucyl-L-phenylalanyl-L-isoleucyl-L-α-glutamyl-L-tryptophyl-L-leucyl-L-lysyl-L-asparaginylglycylglycyl-L-prolyl-L-seryl-L-serylglycyl-L-alanyl-L-prolyl-L-p... Exendin Fragment 9-39 >=95% (HPLC) Exendin-3 (9-39) amide USP/EP/BP GCGR,Glucagon Receptor,Avexitide,Inhibitor,inhibit Exendin-3 (9-39) amide/Avexitide Hexanal Impurity 5 Asp-LEU-SER-LYS-GLN-MET-GLU-GLU-GLU-ALA-VAL-ARG-LEU-PHE-ILE-GLU-TR|p|-LEU-LYS-ASN-GLY-GLY-PRO-SER-SER-GLY-ALA-PRO-PRO-PRO-SER-NH2 Exendin-4 (9-39) 133514-43-9 C149H234N40O47S C149H234N40O47S1 Hormones Obesity Research Exendin Cytokines, Growth Factors and Hormones BioChemical Cell Biology Cell Signaling and Neuroscience Peptide GLP-1 Receptor LigandsObesity Research Cytokines Growth Factors and Hormones (Obesity) ExendinPeptides for Cell Biology Hormones Obesity Peptides Obesity Research Other Obesity Research Products Glucagon receptor and related