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6-AMINO-2,2-DIMETHYL-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE

6-AMINO-2,2-DIMETHYL-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE
6-AMINO-2,2-DIMETHYL-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE structure
CAS No.
1002726-62-6
Chemical Name:
6-AMINO-2,2-DIMETHYL-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE
Synonyms
6-AMino-2,2-diMethyl-2H-p...;6-Amino-2,2-dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3;6-Amino-2,2-dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H);6-AMINO-2,2-DIMETHYL-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE;2H-Pyrido[3,2-b]-1,4-oxazin-3(4H)-one, 6-aMino-2,2-diMethyl-;6-amino-2,2-dimethyl-2H,3H,4H-pyrido[3,2-b][1,4]oxazin-3-one
CBNumber:
CB02453855
Molecular Formula:
C9H11N3O2
Formula Weight:
193.2
MOL File:
1002726-62-6.mol

6-AMINO-2,2-DIMETHYL-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE Properties

Boiling point:
420.3±45.0 °C(Predicted)
Density 
1.256
storage temp. 
Keep in dark place,Sealed in dry,2-8°C
pka
10.79±0.40(Predicted)

6-AMINO-2,2-DIMETHYL-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE Chemical Properties,Uses,Production

Application

6-amino-2,2-dimethyl-4H-pyrido[3,2-b]oxazin-3-one is the key intermediate of Fostamatinib, which is a medication approved by the U.S. Food and Drug Administration since 2018 for the treatment of chronic immune thrombocytopenia (ITP). Fostamatinib is administered orally as a disodium hexahydrate salt and is a prodrug of the active compound tamatinib (R-406), which is a competitive spleen tyrosine kinase (Syk) inhibitor for ATP binding.
Spleen tyrosine kinase (Syk) is a non-receptor cytoplasmic enzyme that is primarily expressed in cells of hematopoietic lineage. Non-receptor tyrosine kinase which mediates signal transduction downstream of a variety of transmembrane receptors, including classical immunoreceptors like the B-cell receptor (BCR). Regulates several biological processes, including innate and adaptive immunity, cell adhesion, osteoclast maturation, platelet activation and vascular development and plays also a crucial role in the innate immune response to fungal, bacterial and viral pathogens.

6-AMINO-2,2-DIMETHYL-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE Preparation Products And Raw materials

Raw materials

Preparation Products


6-AMINO-2,2-DIMETHYL-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE Suppliers

Global( 69)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Synbest Biotech(Hangzhou) Co., Ltd
86-571-88737065
sales@synbestech.com CHINA 171 58
Capot Chemical Co.,Ltd.
+86(0)13336195806 +86-571-85586718
+86-571-85864795 sales@capotchem.com China 20012 60
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 26751 60
Zhejiang ZETian Fine Chemicals Co. LTD
18957127338
stella@zetchem.com CHINA 2007 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 37282 58
Alchem Pharmtech,Inc.
8485655694
sales@alchempharmtech.com United States 63726 58
HENAN BON INDUSTRIAL CO.,LTD
0371-55170695
info@hnbon.com CHINA 26742 58
CONIER CHEM AND PHARMA LIMITED
86-18523575427
sales@conier.com CHINA 47498 58
career henan chemical co
13203830695 0086-371-86658258
0086-371-86658258 factory@coreychem.com CHINA 29864 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
86-021-61999440
contact@trustwe.com CHINA 10003 58

Related articles


View Lastest Price from 6-AMINO-2,2-DIMETHYL-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-11-19 6-amino-2,2-dimethyl-2H-benzo[b][1,4]oxazin-3(4H)-one
1002726-62-6
US $0.00-0.00 / KG 1g 98%min 100kgs/month Shanghai Rlavie Technology Co ltd
2019-12-23 6-AMINO-2,2-DIMETHYL-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE
1002726-62-6
US $1.00 / KG 1KG 99% 200kg Career Henan Chemical Co

1002726-62-6(6-AMINO-2,2-DIMETHYL-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE)Related Search:


  • 6-AMINO-2,2-DIMETHYL-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE
  • 6-AMino-2,2-diMethyl-2H-p...
  • 6-amino-2,2-dimethyl-2H,3H,4H-pyrido[3,2-b][1,4]oxazin-3-one
  • 6-Amino-2,2-dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)
  • 2H-Pyrido[3,2-b]-1,4-oxazin-3(4H)-one, 6-aMino-2,2-diMethyl-
  • 6-Amino-2,2-dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3
  • 1002726-62-6
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