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2,2-dimethyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one

2,2-dimethyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one structure

CAS No.: 20348-21-4

Chemical Name:: 2,2-dimethyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one

Synonyms: Einecs 243-753-2;2,2-Dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H);2,2-dimethyl-4H-pyrido[2,3-e][1,4]oxazin-3-one;2,2-dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one;2,2-dimethyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one;2,2-DIMETHYL-2H-PYRIDO(3,2-B)(1,4)OXAZINE-3(4H)-ONE;2H-Pyrido[3,2-b]-1,4-oxazin-3(4H)-one, 2,2-diMethyl-;2,2-diMethyl-2H,3H,4H-pyrido[3,2-b][1,4]oxazin-3-one

CBNumber:: CB5909443

Molecular Formula:: C9H10N2O2

Molecular Weight:: 178.19

MDL Number:: MFCD10000810

MOL File:: 20348-21-4.mol

MSDS File:: SDS

Last updated:2026-05-28 02:23:05

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2,2-dimethyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one Properties

Boiling point	352.5±37.0 °C(Predicted)
Density	1.176±0.06 g/cm3 (20 ºC 760 Torr)
storage temp.	Store at room temperature
pka	11.13±0.40(Predicted)
form	solid
Appearance	White to off-white Solid
InChI	InChI=1S/C9H10N2O2/c1-9(2)8(12)11-7-6(13-9)4-3-5-10-7/h3-5H,1-2H3,(H,10,11,12)
InChIKey	DMLNXUUGRSBBBR-UHFFFAOYSA-N
SMILES	O1C(C)(C)C(=O)NC2=NC=CC=C12
UNSPSC Code	12352200

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302
Precautionary statements	P301+P312+P330
HS Code	2934999090
Storage Class	11 - Combustible Solids
Hazard Classifications	Acute Tox. 4 Oral
REACH Registrations	Active

2,2-dimethyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one price More Price(47)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	PHB00083	2,2-Dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one AldrichCPR	20348-21-4	1G	$201	2023-06-20	Buy
Apolloscientific	OR49043	2,2-Dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one 98%	20348-21-4	1g	$21	2026-06-04	Buy
Apolloscientific	OR49043	2,2-Dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one 98%	20348-21-4	5g	$24	2026-06-04	Buy
Apolloscientific	OR49043	2,2-Dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one 98%	20348-21-4	25g	$62	2026-06-04	Buy
Apolloscientific	OR49043	2,2-Dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one 98%	20348-21-4	100g	$228	2026-06-04	Buy

Product number	Packaging	Price	Buy
PHB00083	1G	$201	Buy
OR49043	1g	$21	Buy
OR49043	5g	$24	Buy
OR49043	25g	$62	Buy
OR49043	100g	$228	Buy

2,2-dimethyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one Chemical Properties, Uses, Production

Synthesis

16867-03-1

600-00-0

20348-21-4

Step - (i): Synthesis of 2,2-dimethyl-2H-pyrido[3,2-B][1,4]oxazin-3(4H)-one (18.1) 2-Amino-3-hydroxypyridine (5 g, 45.45 mmol) was dissolved in acetone (50 mL) at 20-35 °C and stirred to form a solution. Subsequently K2CO3 (25.09g, 181.81mmol) was added followed by dropwise addition of ethyl 2-bromo-2-methylpropionate (13.29g, 68.18mmol). The reaction mixture was stirred at 70 °C for 16 hours. After completion of the reaction, the mixture was cooled to 20-35 °C and diluted with ice water. The resulting solid was collected by filtration and washed with water to afford the target compound as a white solid (5g, 97% yield). 1H NMR (400MHz, DMSO-d6): [specific NMR data should be added here].

References

[1] Patent: WO2015/71780, 2015, A1. Location in patent: Page/Page column 22
[2] Tetrahedron Letters, 2010, vol. 51, # 14, p. 1852 - 1855
[3] Acta Chemica Scandinavica (1947-1973), 1969, vol. 23, p. 2322 - 2324

2,2-dimethyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one Preparation Products And Raw materials

Raw materials

2-Amino-3-hydroxypyridine Ethyl 2-bromoisobutyrate Acetone Potassium carbonate

Preparation Products

2,2-dimethyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one Suppliers

Global Suppliers ( 78)

Supplier	Tel	Email	Country	ProdList	Advantage
Jinan wonderdrug Technology Co., Ltd	15063369667	1796802755@qq.com	China	312	58
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42917	64
Shanghai Ennopharm Co., Ltd.	+86 (21) 6435-5022		China	4263	65
Shanghai yirong biology science and technology co., ltd	18049974220	3060526242@qq.com	China	999	60
T&W GROUP	021-61551611 13296011611	contact@trustwe.com	China	9884	58
Dtchem Laboratories,（Gan Su）Co.,Ltd.	18993961550 18993966060	sales@techbiochem.com	China	768	61
EnliPharma Technology Co., Ltd	0551-66399836 18955197623	sales@enlipharma.com	China	1875	55
Shanghai Hekang Biotechnology Co., Ltd.	17721021104 18939837085	2880152141@qq.com	China	1840	55
Bide Pharmatech Ltd.	400-164-7117 18317119277	product02@bidepharm.com	China	40000	60
Suzhou Lakestar Pharmatech Co., Ltd.	0512-63970158-603 18018108880	info@lakestarpharma.com	China	399	59

Supplier	Advantage
Jinan wonderdrug Technology Co., Ltd	58
Shanghai Hanhong Scientific Co.,Ltd.	64
Shanghai Ennopharm Co., Ltd.	65
Shanghai yirong biology science and technology co., ltd	60
T&W GROUP	58
Dtchem Laboratories,（Gan Su）Co.,Ltd.	61
EnliPharma Technology Co., Ltd	55
Shanghai Hekang Biotechnology Co., Ltd.	55
Bide Pharmatech Ltd.	60
Suzhou Lakestar Pharmatech Co., Ltd.	59

View Latest Price from 2,2-dimethyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2022-01-04	2,2-dimethyl-2H,3H,4H-pyrido[3,2-b][1,4]oxazin-3-one 20348-21-4		1g	98%min	100kgs/month	Shanghai Rlavie Technology Co ltd
	2019-07-07	2,2-dimethyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one 20348-21-4		1KG	90%-99.9%	500kg	Career Henan Chemical Co

2,2-dimethyl-2H,3H,4H-pyrido[3,2-b][1,4]oxazin-3-one
20348-21-4
98%min
Shanghai Rlavie Technology Co ltd

2,2-dimethyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one
20348-21-4
$0.00
90%-99.9%
Career Henan Chemical Co

2,2-dimethyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one Spectrum

2,2-dimethyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one(20348-21-4)¹HNMR

20348-21-4 (2,2-dimethyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one) Related Search:

N-(3,4-Dichlorobenzyl)-2-methyl-3-oxo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine-2-carboxamide Ethyl 2-methyl-3-oxo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine-2-carboxylate 2-Methyl-N-(3-morpholinopropyl)-3-oxo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine-2-carboxamide 2-Methyl-3-oxo-N-(tetrahydro-2-furanylmethyl)-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine-2-carboxamide N-(2-Methoxybenzyl)-2-methyl-3-oxo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine-2-carboxamide

2-Methyl-3-oxo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine-2-carboxylic acid 2,2-Dimethyl-7-nitro-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one 7-Amino-2,2-dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one 2,2-Dimethyl-6-nitro-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one 2,2-dimethyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one

6-AMINO-2,2-DIMETHYL-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE

1of3

2,2-dimethyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one Einecs 243-753-2 2,2-dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one 2,2-diMethyl-2H,3H,4H-pyrido[3,2-b][1,4]oxazin-3-one 2H-Pyrido[3,2-b]-1,4-oxazin-3(4H)-one, 2,2-diMethyl- 2,2-dimethyl-4H-pyrido[2,3-e][1,4]oxazin-3-one 2,2-Dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H) 2,2-DIMETHYL-2H-PYRIDO(3,2-B)(1,4)OXAZINE-3(4H)-ONE 20348-21-4