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10-Nitrocamptothecin

CAS No.
86639-62-5
Chemical Name:
10-Nitrocamptothecin
Synonyms
RUBETICAN;9-NITRO-CPT;9-Nitro-20(S)-camptothecine;CAMPTOTHECIN, 9-NITRO-20(S)-;10-Nitrocamptothecin ISO 9001:2015 REACH;4α-Ethyl-4-hydroxy-10-nitro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione;(S)-4-Ethyl-4-hydroxy-10-nitro-1H-pyrano[3',4':6,7]-indolizino[1,2-b]quinoline-3,14(4H,12H)-di;(S)-4-Ethyl-4-hydroxy-9-nitro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione;(S)-4-Ethyl-4-hydroxy-10-nitro-1H-pyrano[3',4':6,7]-indolizino[1,2-b]quinoline-3,14(4H,12H)-dione;1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4-hydroxy-9-nitro-, (4S)-
CBNumber:
CB0270140
Molecular Formula:
C20H15N3O6
Molecular Weight:
393.35
MDL Number:
MFCD06656294
MOL File:
86639-62-5.mol
MSDS File:
SDS
Last updated:2023-05-04 17:34:43

10-Nitrocamptothecin Properties

Boiling point 827.4±65.0 °C(Predicted)
Density 1.63±0.1 g/cm3(Predicted)
pka 11.17±0.20(Predicted)

10-Nitrocamptothecin price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 099302 (S)-4-Ethyl-4-hydroxy-10-nitro-1H-pyrano[3',4':6,7]-indolizino[1,2-b]quinoline-3,14(4H,12H)-dione 95+% 86639-62-5 250mg $742 2021-12-16 Buy
Matrix Scientific 099302 (S)-4-Ethyl-4-hydroxy-10-nitro-1H-pyrano[3',4':6,7]-indolizino[1,2-b]quinoline-3,14(4H,12H)-dione 95+% 86639-62-5 1g $1647 2021-12-16 Buy
AK Scientific 9741AF (S)-4-Ethyl-4-hydroxy-10-nitro-1H-pyrano[3',4':6,7]-indolizino[1,2-b]quinoline-3,14(4H,12H)-dione 86639-62-5 1g $2273 2021-12-16 Buy
Crysdot CD32000239 9-Nitrocamptothecin 95+% 86639-62-5 25mg $170 2021-12-16 Buy
DC Chemicals DCX-058 9-Nitrocamptothecin >98%,StandardReferencesGrade 86639-62-5 20mg $280 2021-12-16 Buy
Product number Packaging Price Buy
099302 250mg $742 Buy
099302 1g $1647 Buy
9741AF 1g $2273 Buy
CD32000239 25mg $170 Buy
DCX-058 20mg $280 Buy

10-Nitrocamptothecin Chemical Properties,Uses,Production

Uses

Whether cells can divide depends on the two key points of entering S phase and M phase. Studies have found that 10-Nitrocamptothecin can induce apoptosis. After administration, both S phase and G2M phase of cell growth are delayed. Inhibition occurred throughout the cell cycle and was found to be dose- and time-dependent.

Definition

ChEBI: Rubitecan is a pyranoindolizinoquinoline that is camptothecin in which the hydrogen at position 9 has been replaced by a nitro group. It is a prodrug for 9-aminocamptothecin. It has a role as an antineoplastic agent, an EC 5.99.1.2 (DNA topoisomerase) inhibitor and a prodrug. It is a pyranoindolizinoquinoline, a C-nitro compound, a semisynthetic derivative, a tertiary alcohol and a delta-lactone.

10-Nitrocamptothecin Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 71)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3620 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Shaanxi Pioneer Biotech Co., Ltd .
+8613259417953 sales@pioneerbiotech.com China 3000 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49390 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Shaanxi Dideu Medichem Co. Ltd
18192627656 1012@dideu.com China 3422 58
Neostar United (Changzhou) Industrial Co., Ltd.
+86-519-519-85557386 marketing1@neostarunited.com China 8349 58
ANHUI WITOP BIOTECH CO., LTD
+8615255079626 eric@witopchemical.com China 23556 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 29220 58
Hefei Hirisun Pharmatech Co., Ltd
+8615056975894 shawn@hirisunpharm.com CHINA 9923 58

View Lastest Price from 10-Nitrocamptothecin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
10-Nitrocamptothecin  pictures 2022-05-24 10-Nitrocamptothecin
86639-62-5
US $1.10 / g 1g 99.0% Min 100 Tons Dideu Industries Group Limited
9-Nitrocamptothecin pictures 2020-03-16 9-Nitrocamptothecin
86639-62-5
US $0.10-0.10 / KG 1KG 99% 10000KG Shaanxi Dideu Medichem Co. Ltd
9-Nitrocamptothecin pictures 2019-12-25 9-Nitrocamptothecin
86639-62-5
US $0.10 / KG 1KG 95%-99% 1kg; 50kg; 500kg Career Henan Chemical Co
RUBETICAN CAMPTOTHECIN, 9-NITRO-20(S)- 9-NITRO-CPT 4α-Ethyl-4-hydroxy-10-nitro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione 9-Nitro-20(S)-camptothecine (S)-4-Ethyl-4-hydroxy-10-nitro-1H-pyrano[3',4':6,7]-indolizino[1,2-b]quinoline-3,14(4H,12H)-dione (S)-4-Ethyl-4-hydroxy-9-nitro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione (S)-4-Ethyl-4-hydroxy-10-nitro-1H-pyrano[3',4':6,7]-indolizino[1,2-b]quinoline-3,14(4H,12H)-di 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4-hydroxy-9-nitro-, (4S)- 10-Nitrocamptothecin ISO 9001:2015 REACH 86639-62-5 Natural Anti-cancer Medical Materials and It's Derivatives