(+)-Camptothecin
CAS No.
7689-03-4
Chemical Name:
(+)-Camptothecin
Synonyms
nsc94600;(s)-droxy;nsc100880;Campthecin;CaMpathecin;Camptohecin;CAMPTOTHECIN;CAMPTOTHECINE;CaMpetothecin;Baicalin std.
CBNumber:
CB2381608
Molecular Formula:
C20H16N2O4
Formula Weight:
348.35
MOL File:
7689-03-4.mol
(+)-Camptothecin Properties
Melting point:
260 °C (dec.)(lit.)
alpha
D25 +31.3° (in chloroform-methanol, 8:2)
Boiling point:
482.73°C (rough estimate)
Density
1.3112 (rough estimate)
refractive index
1.5700 (estimate)
storage temp.
2-8°C
solubility
chloroform/methanol (4:1): 4 mg/mL
form
solid
pka
pKa 10.83 (Uncertain)
color
yellow
Water Solubility
insoluble
Merck
14,1735
BRN
631069
InChIKey
VSJKWCGYPAHWDS-FQEVSTJZSA-N
CAS DataBase Reference
7689-03-4(CAS DataBase Reference)
SAFETY
Risk and Safety Statements
Hazard and Precautionary Statements (GHS)
Symbol(GHS):
Signal word:
Danger
Hazard statements:
Code
Hazard statements
Hazard class
Category
Signal word
Pictogram
P-Codes
H301 Toxic if swalloed
Acute toxicity,oral
Category 3
Danger
P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P321 Specific treatment (see … on this label).
P405 Store locked up.
P501 Dispose of contents/container to..…
Manufacturer
Product number
Product description
CAS number
Packaging
Price
Updated
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TCI Chemical
C1495
(S)-(+)-Camptothecin >97.0%(HPLC)
7689-03-4
1g
$368 2018-11-22
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TCI Chemical
C1495
(S)-(+)-Camptothecin >97.0%(HPLC)
7689-03-4
100mg
$60 2018-11-22
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Alfa Aesar
J62523
Camptothecin
7689-03-4
5g
$578 2018-11-13
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Alfa Aesar
J62523
Camptothecin
7689-03-4
1g
$144 2018-11-13
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Cayman Chemical
11694
Camptothecin ≥98%
7689-03-4
50mg
$20 2018-11-13
Buy
(+)-Camptothecin Chemical Properties,Uses,Production
Chemical Properties
light yellow crystal powde
Uses
Antitumor alkaloid. Binds irreversible to the DNA-topoisomerase I complex, inhibiting the reassociation of DNA after cleavage by topoisomerase I and traps the enzyme in a covalent linkage with DNA. A cytotoxic antitumor agent
Uses
antineoplastic
Uses
Antitumor agent;Topoisomerase I inhibitor
Uses
10-hydroxycamptothecine precursor, topoisomerase inhibitor, binds irreversibly to DNA-topoisomerase I complex
Definition
ChEBI: A pyranoindolizinoquinoline that is pyrano[3',4':6,7]indolizino[1,2-b]quinoline which is substituted by oxo groups at positions 3 and 14, and by an ethyl group and a hydroxy group at position 4 (the S enantiomer).
Biological Activity
Cytotoxic plant alkaloid with antitumor properties; prototypic DNA topoisomerase I inhibitor.
(+)-Camptothecin Preparation Products And Raw materials
Raw materials
Preparation Products
(+)-Camptothecin Suppliers
Global( 375)Suppliers
Belgium 1
Canada 2
China 259
Europe 5
Germany 10
India 5
Japan 4
Switzerland 3
Ukraine 1
United Kingdom 18
United States 67
Global 375
View Lastest Price from (+)-Camptothecin manufacturers
7689-03-4((+)-Camptothecin)Related Search:
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,Jurkat cell Lysate (Camptothecin-treated)
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1,6-DIHYDROXY-7-GLUCURONOSYLFLAVONE
(20S)-CAMPTOTHECIN
4-ETHYL-4-HYDROXY-1H-PYRANO[3',4':6,7]INDOLIZINO[1,2-B]QUINOLINE-3,14(4H,12H)DIONE
5,6-DIHYDROXY-7-GLUCURONOSYLFLAVONE
5,6-DIHYDROXY-4-OXO-2-PHENYL-4H-1-BENZOPYRAN-7-YL BETA-D-GLUCOPYRANOSIDURONIC ACID
CAMPTOTHECIN, CAMPTOTHECA ACUMINATA
CAMPTOTHECINE
(+)-CAMPTOTHECIN
CAMPTOTHECIN
(s)-droxy
1h-pyrano(3’,4’:6,7)indolizino(1,2-b)quinoline-3,14(4h,12h)-dione,4-ethyl-4-hy
CaMpathecin
CaMpetothecin
(4S)-4-Ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
Topotecan Related CoMpound C
CaMptothecin(NATURAL)
(+)-Camptothecin
4-Ethyl-4-hydroxy-1H-pyrano-[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
Campthecin
20(s)-camptothecine
21,22-secocamptothecin-21-oicacidlactone
1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-
3,14(4H,12H)-dione,4-ethyl-4-hydroxy-, (S)-
(S)-4-Ethyl-4-hydroxyl-1H-pyrano-[3',4':6,7]indolizino[1,2-b]quinoline-3, 14(4H,12H)-dione
(20RS)-Camptothecin
(RS)-Camptothecin
rac-4α*-Hydroxy-4-ethyl-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-dione
d-Camptothecin
(+)-Camptothecin,98%
Antibiotics
Antibiotics A-F
Antibiotics A to Z
BioChemical
Alkaloids
Antineoplastic
Camptothecin series
7689-03-4
chemical reagent
pharmaceutical intermediate
phytochemical
reference standards from Chinese medicinal herbs (TCM).
7869-03-4
5,6-DIHYDROXY-4-OXO-2-PHENYL-4H-1-BENZOPYRAN-7-YL BETA-D-GLUCOPYRANOSIDURONIC ACI
Camptothecin,from Camptotheca acuminata
4-Ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza
-dibenzo[b,h]fluorene-3,13-dione
nsc100880
nsc94600
(S)-4-ETHYL-4-HYDROXY-1,12-DIHYDRO-4H-2-OXA-6,12A-DIAZA-DIBENZO[B,H]FLUORENE-3,13-DIONE
(S)-4-ETHYL-4-HYDROXY-1H-PYRANO-[3',4':6,7]INDOLIZINO[1,2-B]QUINOLINE-3,14(4H,12H)-DIONE
(S)-(+)-CAMPTOTHECIN
Camptothecin,95%
Camptohecin
Baicalin std.
(S)-(+)-CAMPTOTHECINE
CAMPTOTHECINE 95-98%
CAMPTOTHECIN(P)
camptothecincamptothecine
Irinotecan Impurity 14
C20H16N2O4
