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5-Chloronicotinic acid

CAS No.
22620-27-5
Chemical Name:
5-Chloronicotinic acid
Synonyms
AKOS BBS-00001378;IFLAB-BB F1957-0008;5-Chloronicotinic ac;5-CHLORONICOTINIC ACID;5-chlorine nicotinic acid;5-Chloronicotinic Acid >5-chloropyridine-3-carboxylicaci;5-CHLOROPYRIDINE-3-CARBOXYLIC ACID;4-chloropyridine-4-carboxylic acid;3-Pyridinecarboxylic acid, 5-chloro-
CBNumber:
CB0293576
Molecular Formula:
C6H4ClNO2
Molecular Weight:
157.55
MDL Number:
MFCD00128901
MOL File:
22620-27-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-10-15 13:42:20

5-Chloronicotinic acid Properties

Melting point 169-171°C
Boiling point 303.7±22.0 °C(Predicted)
Density 1.470±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
form powder to crystal
pka 3.10±0.10(Predicted)
color White to Almost white
InChI InChI=1S/C6H4ClNO2/c7-5-1-4(6(9)10)2-8-3-5/h1-3H,(H,9,10)
InChIKey XYLPLVUYPAPCML-UHFFFAOYSA-N
SMILES C1=NC=C(Cl)C=C1C(O)=O
CAS DataBase Reference 22620-27-5(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
Hazard Codes  Xi,Xn
Risk Statements  22
HazardClass  IRRITANT
HS Code  29333990
NFPA 704
0
2 0

5-Chloronicotinic acid price More Price(85)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical C2399 5-Chloronicotinic Acid >95.0%(GC)(T) 22620-27-5 1g $37 2026-04-30 Buy
TCI Chemical C2399 5-Chloronicotinic Acid >95.0%(GC)(T) 22620-27-5 5g $122 2026-04-30 Buy
TRC TRC-C373670-5G 5-Chloronicotinic Acid 22620-27-5 5g $154 2026-06-03 Buy
TRC TRC-C373670-1G 5-Chloronicotinic Acid 22620-27-5 1g $97 2026-06-03 Buy
TRC TRC-C373670-10G 5-Chloronicotinic Acid 22620-27-5 10g $256 2026-06-03 Buy
Product number Packaging Price Buy
C2399 1g $37 Buy
C2399 5g $122 Buy
TRC-C373670-5G 5g $154 Buy
TRC-C373670-1G 1g $97 Buy
TRC-C373670-10G 10g $256 Buy

5-Chloronicotinic acid Chemical Properties, Uses, Production

Preparation

Ethyl 5-chloronicotinic acid (10.5 g) was added to an aqueous solution of 1N NaOH (84.9 mL). The resulting reaction mixture was reacted at room temperature for several hours, and then transferred to 60 degrees Celsius to continue the reaction for 1 hour. The pH of the reaction solution was adjusted to 4-5 with hydrochloric acid, and a precipitate was observed to form. The precipitate was filtered to obtain the product 5-chloronicotinic acid, which was a colorless solid with a yield of 6.9 g.

Chemical Properties

Off white powder

Uses

5-Chloronicotinic Acid is used as reagent/reactant luminescence and hydrothermal preparation of cobalt/cadmium/lead chloronicotinate phenanthroline MOF.

20825-98-3
22620-27-5
Synthesis of 5-Chloronicotinic acid from ethyl 5-chloropyridine-3-carboxylate

5-Chloronicotinic acid Preparation Products And Raw materials

Global Suppliers ( 261)
Supplier Tel Email Country ProdList Advantage
Fuxin Yuke Chemical Technology Co., Ltd. 0418-6696667 15724496333 2630398044@qq.com China 181 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
future industrial shanghai co., ltd 400-0066400 13621662912 sales@jonln.com China 1989 65
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Beijing HwrkChemical Technology Co., Ltd 89508211 18501085097 sales.bj@hwrkchemical.com China 9409 55
Energy Chemical 400-0056266 18918157536; sales8178@energy-chemical.com China 45000 61
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Jia Xing Isenchem Co.,Ltd 0573-85285100 18627885956 isenchem@163.com China 9388 66

View Latest Price from 5-Chloronicotinic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-Chloronicotinic acid pictures 2026-10-15 5-Chloronicotinic acid
22620-27-5
1KG 0.99 100 KG Shanghai Massive Chemical Technology Co., Ltd
5-Chloronicotinic acid  pictures 2026-08-20 5-Chloronicotinic acid
22620-27-5
$1.10 1g 99.00% 100 Tons Min Dideu Industries Group Limited
5-Chloronicotinic acid pictures 2025-04-04 5-Chloronicotinic acid
22620-27-5
1KG 98% 1ton Henan Aochuang Chemical Co.,Ltd.

5-Chloronicotinic acid Spectrum

AKOS BBS-00001378 5-CHLORONICOTINIC ACID/5-CHLOROPYRIDINE-3-CARBOXYLIC ACID 5-CHLOROPYRIDINE-3-CARBOXYLIC ACID 98% 5-CHLOROPYRIDINE-3-CARBOXYLIC ACID 5-CHLORONICOTINIC ACID IFLAB-BB F1957-0008 5-Chloronicotinic ac 5-chlorine nicotinic acid 5-Chloropyridine-3-carboxylic acid, 3-Carboxy-5-chloropyridine N-[4-(butylsulfamoyl)-2-nitrophenyl]-1-hydroxy-2-naphthalenecarboxamide 5-Chloronicotinic Acid > 3-Pyridinecarboxylic acid, 5-chloro- 5-Chloronicotinic acid ISO 9001:2015 REACH 4-chloropyridine-4-carboxylic acid 5-chloropyridine-3-carboxylicaci 22620-27-5 2620-27-5 10177-29-5 C6H4ClNO2 Heterocycle-Pyridine series pharmacetical Carboxylic Acids Pyridines Carboxylic Acids