ChemicalBook >> CAS DataBase List >>L-DIHYDROOROTIC ACID
L-DIHYDROOROTIC ACID
- CAS No.
- 5988-19-2
- Chemical Name:
- L-DIHYDROOROTIC ACID
- Synonyms
- DNTPS;Dihydroorotic acid;DIHYDRO-L-OROTIC ACID;L-HYDROOROTIC ACID;(S)-Dihydroorotate;(S)-2,6-dioxohexahydropyrimidine-4-carboxylic acid;DI-H-OROTATE;(S)-di-H-orotate;L-4,5-dihydroorotic;L-DIHYDROOROTIC ACID
- CBNumber:
- CB0386533
- Molecular Formula:
- C5H6N2O4
- Molecular Weight:
- 158.11
- MDL Number:
- MFCD00085339
- MOL File:
- 5988-19-2.mol
- MSDS File:
- SDS
Last updated:2023-09-21 15:25:22
| Melting point | 254-255 °C (dec.)(lit.) |
|---|---|
| Boiling point | 283.16°C (rough estimate) |
| Density | 1.523 |
| refractive index | 1.5090 (estimate) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | DMSO (Slightly), Water (Slightly, Heated, Sonicated) |
| pka | 2.82±0.20(Predicted) |
| form | Powder |
| color | White to off-white |
| Water Solubility | Soluble in water (partly), and dimethyl formamide. |
| InChIKey | UFIVEPVSAGBUSI-REOHCLBHSA-N |
| CAS DataBase Reference | 5988-19-2(CAS DataBase Reference) |
| FDA UNII | 4LPL64ZNA5 |
| NIST Chemistry Reference | Orotic acid, dihydro-, l-(5988-19-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
L-DIHYDROOROTIC ACID price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | D7128 | L-Dihydroorotic acid ≥99% | 5988-19-2 | 1g | $296 | 2024-03-01 | Buy |
| Sigma-Aldrich | D7128 | L-Dihydroorotic acid ≥99% | 5988-19-2 | 5g | $399.6 | 2024-03-01 | Buy |
| Alfa Aesar | H60429 | L-Dihydroorotic acid, 98% | 5988-19-2 | 1g | $156 | 2024-03-01 | Buy |
| Alfa Aesar | H60429 | L-Dihydroorotic acid, 98% | 5988-19-2 | 5g | $613 | 2024-03-01 | Buy |
| Sigma-Aldrich | D7128 | L-Dihydroorotic acid ≥99% | 5988-19-2 | 500mg | $167 | 2024-03-01 | Buy |
L-DIHYDROOROTIC ACID Chemical Properties,Uses,Production
Chemical Properties
White to off-white crystalline powder
Uses
L-Dihydroorotic acid a metabolite.
Definition
ChEBI: (S)-dihydroorotic acid is the (S)-enantiomer of dihydroorotic acid that is an intermediate in the metabolism of pyridine. It has a role as a Saccharomyces cerevisiae metabolite, a human metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a conjugate acid of a (S)-dihydroorotate. It is an enantiomer of a (R)-dihydroorotic acid.
Biochem/physiol Actions
L-Dihydroorotic acid (DHO) serves as a substrate for dihydroorotate dehydrogenase (DHODH), an enzyme in the de novo synthesis of pyrimidine. Inhibition of DHOH by its inhibitors causes a large accumulation of upstream metabolite DHO and a reduction in the uridine levels. Therefore, DHO and uridine can be used as biomarkers for pyrimidine synthesis for the clinical development of DHOH inhibitors.
L-DIHYDROOROTIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 282)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12456 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15932 | 58 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3012 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
View Lastest Price from L-DIHYDROOROTIC ACID manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-09-21 | L-DIHYDROOROTIC ACID
5988-19-2
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd | |
 |
2023-09-06 | L-DIHYDROOROTIC ACID
5988-19-2
|
US $0.00-0.00 / KG | 1KG | 99% | 500000kg | Hebei Guanlang Biotechnology Co., Ltd. | |
 |
2023-06-26 | L-Dihydroorotic acid
5988-19-2
|
US $150.00 / ASSAYS | 10g | more than 99.6% | 500kg/month | Hebei Mingeng Biotechnology Co., Ltd |
-
- L-DIHYDROOROTIC ACID
5988-19-2
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd
-
- L-DIHYDROOROTIC ACID
5988-19-2
- US $0.00-0.00 / KG
- 99%
- Hebei Guanlang Biotechnology Co., Ltd.
-
- L-Dihydroorotic acid
5988-19-2
- US $150.00 / ASSAYS
- more than 99.6%
- Hebei Mingeng Biotechnology Co., Ltd
5988-19-2(L-DIHYDROOROTIC ACID)Related Search:
UDP SODIUM SALT
URIDINE 5'-DIPHOSPHORIC ACID SODIUM SALT
2'-Deoxyuridine
Cytidine-5'-diphosphate disodium salt
Inosine
CTP xsodium
ATP disodium salt
Uridine-5'-diphosphate disodium salt
Orotic acid
Sodium phosphate tribasic dodecahydrate
1of4
L-DIHYDROOROTIC ACID
(S)-2,6-Dioxohexahydro-4-pyrimidinecarboxylic acid
2,6-Dioxohexahydro-4-pyrimidinecarboxylic acid
L-4,5-Dihydroorotic acid~(S)-(+)-2,6-Dioxohexahydro-4-pyrimidinecarboxylic acid
(S)-(+)-HYDROOROTIC ACID
(4S)-2,6-dioxo-1,3-diazinane-4-carboxylic acid
L-4,5-dihydroorotic acid
(S)-4,5-dihydroorotate
(S)-4,5-dihydroorotic acid
(S)-4-pyrimidinecarboxylic acid
(S)-di-H-orotate
4,5-dihydro-L-orotate
DI-H-OROTATE
L-4,5-dihydroorotate
4-Pyrimidinecarboxylic acid, hexahydro-2,6-dioxo-, (4S)-
L-4,5-dihydroorotic
Adenosine-5-triphosphoric acid Na2
Adenosine-5'-diphosphoric acid Na2
Deoxyribonucein acid(fish sperm)
Guanosine-5-diphosphate disodiun
Guanosine-5-monophosphate disodiun
Guanosine-5'-triphosphate disodiun
t-Ribonuclein acid,yeast
4-Pyrimidinecarboxylic acid, hexahydro-2,6-dioxo-
2,6-Dioxohexahydro-4-pyrimidinecarboxylic acid, L-Hydroorotic acid, Dihydro-L-orotic acid
(4S)-2,6-Dioxohexahydropyrimidine-4-carboxylic acid
(6S)-Hexahydro-2,4-dioxopyrimidine-6β-carboxylic acid
(S)-Dihydroorotic acid
Hexahydro-2,6-dioxopyrimidine-4α-carboxylic acid
Inosine-5-triphosphate trisodium
Ribonuclein acid,yeast
Deoxyribonucleoside- 5′-triphosphate
(4S)-2,6-dioxo-1,3-diazinane-4-carboxylate
L-5,6-Dihydroorotic acid
L-DIHYDROOROTIC ACID USP/EP/BP
(S)-2,6-Dioxohexahydropyrimidine-4-carboxylic acid,L-4,5-Dihydroorotic acid~(S)-(+)-2,6-Dioxohexahydro-4-pyrimidinecarboxylic acid,L-Dihydroorotic acid,L-Dihydroorotic Acid
L-HYDROOROTIC ACID
DIHYDRO-L-OROTIC ACID
(S)-Dihydroorotate
(S)-2,6-dioxohexahydropyrimidine-4-carboxylic acid
DNTPS
Dihydroorotic acid
(S)-dihydrooroticaci
L-4, 5-dihydrowhey acid
L-DihydrooroticacidL-Dihydrooroticacid
5988-19-2
BioChemical
Nucleotide
Metabolomics
Metabolites and Cofactors on the Metabolic Pathways Chart
Metabolic Pathways
Heterocycles
Miscellaneous Biochemicals
Amino Acid Derivatives
5988-19-2