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LIPOXIN B4

CAS No.
98049-69-5
Chemical Name:
LIPOXIN B4
Synonyms
LXB4;LIPOXIN B4;5(S),14(R)-Lipoxin B4;UXVRTOKOJOMENI-WLPVFMORSA-N;5(S), 14(R), 15(S)-TRIHYDROXYEICOSA-6E,8Z,10E,12E-TETRAENOIC ACID;(5S,14R,15S)-5,14,15-Trihydroxy-(6E,8Z,10E,12E)-eicosatetraenoic acid;(5S,6E,8Z,10E,12E,14R,15S)-5,14,15-Trihydroxy-6,8,10,12-icosatetraenoic acid;(5S,6E,8Z,10E,12E,14R,15S)-5,14,15-trihydroxyicosa-6,8,10,12-tetraenoic acid;6,8,10,12-Eicosatetraenoic acid, 5,14,15-trihydroxy-, (5S,6E,8Z,10E,12E,14R,15S)-
CBNumber:
CB0701080
Molecular Formula:
C20H32O5
Molecular Weight:
352.47
MDL Number:
MFCD00870250
MOL File:
98049-69-5.mol
Last updated:2023-06-08 09:03:07

LIPOXIN B4 Properties

storage temp. -20°C
solubility DMF: >50 mg/ml; Ethanol: >50 mg/ml; PBS pH 7.2: >1 mg/ml (from 13(S)-HODE)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
Hazard Codes  F,Xi
Risk Statements  11-36/37/38
Safety Statements  16-26-36
NFPA 704
3
2 0

LIPOXIN B4 price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 90420 Lipoxin B4 ≥95% 98049-69-5 25μg $274 2024-03-01 Buy
Cayman Chemical 90420 Lipoxin B4 ≥95% 98049-69-5 50μg $519 2024-03-01 Buy
Cayman Chemical 90420 Lipoxin B4 ≥95% 98049-69-5 100μg $980 2024-03-01 Buy
Usbiological 396443 LXB4 98049-69-5 48Tests $588 2021-12-16 Buy
TRC L468770 5(S),14(R)-LipoxinB4 98049-69-5 50μg $600 2021-12-16 Buy
Product number Packaging Price Buy
90420 25μg $274 Buy
90420 50μg $519 Buy
90420 100μg $980 Buy
396443 48Tests $588 Buy
L468770 50μg $600 Buy

LIPOXIN B4 Chemical Properties,Uses,Production

Uses

Lipoxins are a series of anti-inflammatory lipid mediators whose brief appearance generally signals the resolution of inflammation. Lipoxin A4 (LXA4) is a potent inhibitor of leukotriene (LT)-triggered polymorphonuclear neutrophil (PMN)-endothelial cell interaction and also blocks PMN migration stimulated by LTB4. LXB4 is a positional isomer of LXA4 produced by the metabolism of 15-HETE or 15-HpETE by human leukocytes. At a concentration of 10-7 M, LXB4 inhibits PMN migration stimulated by LTB4 and inhibits LTB4-induced adhesion of PMNs with an IC50 value of ~3 X 10-10 M.

Uses

5(S),14(R)-Lipoxin B4 is a positional isomer of LXA4.

Definition

ChEBI: Lipoxin B4 is a C20 hydroxy fatty acid having (5S)-, (14R)- and (15S)-hydroxy groups as well as (6E)- (8Z)-, (10E)- and (12E)-double bonds. It has a role as a human metabolite. It is a lipoxin, a long-chain fatty acid and a hydroxy polyunsaturated fatty acid. It is a conjugate acid of a lipoxin B4(1-).

LIPOXIN B4 Preparation Products And Raw materials

Raw materials

Preparation Products

LIPOXIN B4 Suppliers

Global( 30)Suppliers
Supplier Tel Email Country ProdList Advantage
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Shanghai Universal Biotech Co.,Ltd 18768175414 gaojun@univ-bio.com China 24998 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24131 58
Shanghai Yiyan Biotechnology Co. , Ltd. 021-69985186 13611928337 3427709316@qq.com China 7984 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58
(5S,6E,8Z,10E,12E,14R,15S)-5,14,15-trihydroxyicosa-6,8,10,12-tetraenoic acid (5S,6E,8Z,10E,12E,14R,15S)-5,14,15-Trihydroxy-6,8,10,12-icosatetraenoic acid LXB4 5(S),14(R)-Lipoxin B4 (5S,14R,15S)-5,14,15-Trihydroxy-(6E,8Z,10E,12E)-eicosatetraenoic acid 5(S), 14(R), 15(S)-TRIHYDROXYEICOSA-6E,8Z,10E,12E-TETRAENOIC ACID LIPOXIN B4 UXVRTOKOJOMENI-WLPVFMORSA-N 6,8,10,12-Eicosatetraenoic acid, 5,14,15-trihydroxy-, (5S,6E,8Z,10E,12E,14R,15S)- 98049-69-5