7H-Cyclopenta[b]pyridin-7-one, 5,6-dihydro-
![7H-Cyclopenta[b]pyridin-7-one, 5,6-dihydro- Structure](CAS/GIF/31170-78-2.gif)
- CAS No.
- 31170-78-2
- Chemical Name:
- 7H-Cyclopenta[b]pyridin-7-one, 5,6-dihydro-
- Synonyms
- 5H-cyclopenta[b]pyridin-7(6H)-one;5,6-Dihydro-7H-cyclopenta[b]pyridin-7-one;7H-cyclopenta[b]pyridin-7-one;5H-Cyclopenta[b]pyridin-7(6H);5,6-Dihydro-[1]pyrindin-7-one;7H-Cyclopenta[b]pyridin-5-one;5H-CYCLOPENTATBPYRIDIN-7(6H)-ONE;5H,6H,7H-cyclopenta[b]pyridin-7-one;5,6-Dihydro-7H-cyclopenta[b]pyridin-7-on;7H-cyclopenta[b]pyridin-5-one,6,7-dihydro-
- CBNumber:
- CB0735294
- Molecular Formula:
- C8H7NO
- Molecular Weight:
- 133.15
- MDL Number:
- MFCD07778341
- MOL File:
- 31170-78-2.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| HS Code | 2933998090 |
7H-Cyclopenta[b]pyridin-7-one, 5,6-dihydro- price More Price(50)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 162005 | 5,6-Dihydro-7H-cyclopenta[b]pyridin-7-one | 31170-78-2 | 100mg | $418 | 2026-06-03 | Buy |
| Apolloscientific | OR951739 | 5,6-Dihydro-7h-cyclopenta[b]pyridin-7-one 97% | 31170-78-2 | 100mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR951739 | 5,6-Dihydro-7h-cyclopenta[b]pyridin-7-one 97% | 31170-78-2 | 250mg | $24 | 2026-06-04 | Buy |
| Apolloscientific | OR951739 | 5,6-Dihydro-7h-cyclopenta[b]pyridin-7-one 97% | 31170-78-2 | 1g | $40 | 2026-06-04 | Buy |
| Apolloscientific | OR951739 | 5,6-Dihydro-7h-cyclopenta[b]pyridin-7-one 97% | 31170-78-2 | 5g | $168 | 2026-06-04 | Buy |
7H-Cyclopenta[b]pyridin-7-one, 5,6-dihydro- Chemical Properties, Uses, Production
Uses
5,6-Dihydro-7H-cyclopenta[b]pyridin-7-one, is an intermediate for the synthesis of pharmaceutical and biological compounds. It can be used for synthesis of new propargylated 1-pyrindane derivatives as Rasagiline (R126000) analogues, used as an antiparkinsonian agent.
Synthesis
![(Z)-7-benzylidene-6,7-dihydro-5H-cyclopenta[b]pyridine](/CAS/20150408/GIF/74701-35-2.gif)
74701-35-2
![7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO-](/CAS/GIF/31170-78-2.gif)
31170-78-2
General procedure for the synthesis of 5,6-dihydro-7H-cyclopenta[b]pyridin-7-one from the compound (CAS: 74701-35-2): 5-benzylidene-6,7-dihydro-5H-[1]pyrazine (12.18 g, 58.8 mmol) was dissolved in 200 mL of mixed solvent of MeOH:CH2Cl2 (1:1), and the ozonolysis reaction was performed at 7 psi and 1.5 amperes for the ozonolysis reaction. Upon completion of the reaction, the reaction mixture was quenched with thiourea, filtered and concentrated. The product was purified by column chromatography using hexane:EtOAc (4:1) as eluent to afford 5.96 g (76% yield) of 5,6-dihydro-7H-cyclopenta[b]pyridin-7-one. The structure of the product was confirmed by 1H NMR (300 MHz, CDCl3): δ 2.75-2.82 (m, 2H), 3.15-3.22 (m, 2H), 7.47 (q, J = 4.40, 3.52 Hz, 1H), 7.91 (d, J = 8.79 Hz, 1H), 8.79 (d, J = 5.28 Hz, 1H).
References
[1] Patent: US2008/255239, 2008, A1. Location in patent: Page/Page column 32
[2] Journal of Organic Chemistry, 1984, vol. 49, # 12, p. 2208 - 2212
[3] Journal of Medicinal Chemistry, 2008, vol. 51, # 3, p. 392 - 395
7H-Cyclopenta[b]pyridin-7-one, 5,6-dihydro- Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Tongchuang Pharma(Suzhou). Co., Ltd. | 0512-63263366 18912765016 | tongtf110@sina.com | China | 988 | 62 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Tetranov Biopharm | 13526569071 | sales@leadmedpharm.com | China | 7880 | 64 |
| Accela ChemBio Co.,Ltd. | 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8663 | 57 |
| Heterochem | 027-88041443 13072715837 | sales@hetero-chem.com | China | 695 | 58 |
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9509 | 58 |
| Nanjing Norris-Pharm Technology Co., Ltd | 13901585132 | sales@norris-pharm.com | China | 8869 | 55 |
| Shanghai Keepontech Co.,Ltd | 021-54849683 13601642561 | sales@keepontech.com | China | 1000 | 59 |
View Latest Price from 7H-Cyclopenta[b]pyridin-7-one, 5,6-dihydro- manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
![7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO- pictures](/ProductImageEN/2021-07/Small/e26020f1-7eb3-4588-982b-bff026484d90.jpg) |
2021-07-13 | 7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO-
31170-78-2
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
![7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO- pictures](/ProductImageEN/2021-07/Small/f6646082-31ce-4331-a158-08ce20fc9507.jpg) |
2021-07-10 | 7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO-
31170-78-2
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
![5,6-dihydrocyclopenta[b]pyridin-7-one pictures](https://img.chemicalbook.com/ProductImageEN/2020-1/Small/6bf13410-1d88-495f-b1e4-f2f0f396bbf9.jpg) |
2020-01-10 | 5,6-dihydrocyclopenta[b]pyridin-7-one
31170-78-2
|
$5.50 | 1ASSAYS | 98%min | 1kg,10kg,100kg | Career Henan Chemical Co |
-
- 7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO-
31170-78-2
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO-
31170-78-2
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 5,6-dihydrocyclopenta[b]pyridin-7-one
31170-78-2
- $5.50
- 98%min
- Career Henan Chemical Co
