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ChemicalBook >> CAS DataBase List >>7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO-

7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO-

7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO- Structure
7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO- structure
CAS No.
31170-78-2
Chemical Name:
7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO-
Synonyms
7H-Cyclopenta[b]pyridin-5-one;7H-cyclopenta[b]pyridin-7-one;5H-Cyclopenta[b]pyridin-7(6H);5,6-Dihydro-[1]pyrindin-7-one;5H-CYCLOPENTATBPYRIDIN-7(6H)-ONE;5H-cyclopenta[b]pyridin-7(6H)-one;5H,6H,7H-cyclopenta[b]pyridin-7-one;5,6-Dihydro-7H-cyclopenta[b]pyridin-7-one;7H-cyclopenta[b]pyridin-5-one,6,7-dihydro-;7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO-
CBNumber:
CB0735294
Molecular Formula:
C8H7NO
Molecular Weight:
133.15
MDL Number:
MFCD07778341
MOL File:
31170-78-2.mol
Last updated:2025-07-24 18:13:46
Product description Number Pack Size Price
5,6-Dihydro-7H-cyclopenta[b]pyridin-7-one D448805 100mg $125
5,6-Dihydro-7H-cyclopenta[b]pyridin-7-one D448805 1g $850
5H-Cyclopenta[b]pyridin-7(6H)-one FC144364 2g $400
5H-Cyclopenta[b]pyridin-7(6H)-one 99.43% CS-W003423 250mg $51
5H-Cyclopenta[b]pyridin-7(6H)-one FC144364 250mg $100
More product size
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7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO- Properties

Melting point 118-120 °C
Boiling point 130-150 °C(Press: 0.1 Torr)
Density 1.230±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Store in freezer, under -20°C
pka 3.50±0.20(Predicted)
Appearance Gray to dark gray Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338
HS Code  2933998090

7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO- price More Price(26)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC D448805 5,6-Dihydro-7H-cyclopenta[b]pyridin-7-one 31170-78-2 100mg $125 2021-12-16 Buy
TRC D448805 5,6-Dihydro-7H-cyclopenta[b]pyridin-7-one 31170-78-2 1g $850 2021-12-16 Buy
Biosynth Carbosynth FC144364 5H-Cyclopenta[b]pyridin-7(6H)-one 31170-78-2 2g $400 2021-12-16 Buy
ChemScene CS-W003423 5H-Cyclopenta[b]pyridin-7(6H)-one 99.43% 31170-78-2 250mg $51 2021-12-16 Buy
Biosynth Carbosynth FC144364 5H-Cyclopenta[b]pyridin-7(6H)-one 31170-78-2 250mg $100 2021-12-16 Buy
Product number Packaging Price Buy
D448805 100mg $125 Buy
D448805 1g $850 Buy
FC144364 2g $400 Buy
CS-W003423 250mg $51 Buy
FC144364 250mg $100 Buy

7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO- Chemical Properties,Uses,Production

Uses

5,6-Dihydro-7H-cyclopenta[b]pyridin-7-one, is an intermediate for the synthesis of pharmaceutical and biological compounds. It can be used for synthesis of new propargylated 1-pyrindane derivatives as Rasagiline (R126000) analogues, used as an antiparkinsonian agent.

Synthesis

(Z)-7-benzylidene-6,7-dihydro-5H-cyclopenta[b]pyridine

74701-35-2

7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO-

31170-78-2

General procedure for the synthesis of 5,6-dihydro-7H-cyclopenta[b]pyridin-7-one from the compound (CAS: 74701-35-2): 5-benzylidene-6,7-dihydro-5H-[1]pyrazine (12.18 g, 58.8 mmol) was dissolved in 200 mL of mixed solvent of MeOH:CH2Cl2 (1:1), and the ozonolysis reaction was performed at 7 psi and 1.5 amperes for the ozonolysis reaction. Upon completion of the reaction, the reaction mixture was quenched with thiourea, filtered and concentrated. The product was purified by column chromatography using hexane:EtOAc (4:1) as eluent to afford 5.96 g (76% yield) of 5,6-dihydro-7H-cyclopenta[b]pyridin-7-one. The structure of the product was confirmed by 1H NMR (300 MHz, CDCl3): δ 2.75-2.82 (m, 2H), 3.15-3.22 (m, 2H), 7.47 (q, J = 4.40, 3.52 Hz, 1H), 7.91 (d, J = 8.79 Hz, 1H), 8.79 (d, J = 5.28 Hz, 1H).

References

[1] Patent: US2008/255239, 2008, A1. Location in patent: Page/Page column 32
[2] Journal of Organic Chemistry, 1984, vol. 49, # 12, p. 2208 - 2212
[3] Journal of Medicinal Chemistry, 2008, vol. 51, # 3, p. 392 - 395

7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO- Preparation Products And Raw materials

Raw materials

(Z)-7-benzylidene-6,7-dihydro-5H-cyclopenta[b]pyridine Oxygen Dichloromethane Ozone Methanol
Thiourea

1of2

Preparation Products

5H-Cyclopenta[b]pyridin-7-ol, 6,7-dihydro,(7R)-

7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO- Suppliers

Global( 124)Suppliers
Supplier Tel Email Country ProdList Advantage
Accela ChemBio Inc. 		+1-858-6993322 info@accelachem.com United States 21193 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49977 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29795 58
Antai Fine Chemical Technology Co.,Limited 		18503026267 info@antaichem.com CHINA 9636 58
Zhengzhou Alfa Chemical Co.,Ltd 		+8618530059196 sale04@alfachem.cn China 11727 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
ANHUI WITOP BIOTECH CO., LTD 		+8615255079626 eric@witopchemical.com China 23541 58
Shaanxi Dideu Medichem Co. Ltd 		+86-029-89586680 +86-18192503167 1026@dideu.com China 7099 58
Baoji Guokang Healthchem Co., Ltd. 		+86-0917-3909592 +86-13892490616 gksales1@gk-bio.com China 9206 58
Supplier Advantage
Accela ChemBio Inc. 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
Antai Fine Chemical Technology Co.,Limited 		58
Zhengzhou Alfa Chemical Co.,Ltd 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
ANHUI WITOP BIOTECH CO., LTD 		58
Shaanxi Dideu Medichem Co. Ltd 		58
Baoji Guokang Healthchem Co., Ltd. 		58

View Lastest Price from 7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO- pictures 2025-06-25 7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO-
31170-78-2
 US $1.10 / g 1g 99.0% min 100 tons min Shaanxi Dideu Medichem Co. Ltd
7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO- pictures 2021-07-13 7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO-
31170-78-2
 US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO- pictures 2021-07-10 7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO-
31170-78-2
 US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd

7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO- Spectrum

7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO-(31170-78-2)1HNMR

31170-78-2(7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO-)Related Search:

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