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Thiourea

Thiourea
Thiourea structure
CAS No.
62-56-6
Chemical Name:
Thiourea
Synonyms
THU;THIO;250g;tsizp34;Thiurea;(NH2)2CS;Sulourea;thio-ure;thiouree;Tsizp 34
CBNumber:
CB9854008
Molecular Formula:
CH4N2S
Formula Weight:
76.12
MOL File:
62-56-6.mol
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Thiourea Properties

Melting point:
171 °C
Boiling point:
263.89°C (estimate)
Density 
1.405
refractive index 
1.5300 (estimate)
storage temp. 
Store at RT.
solubility 
water: soluble137g/L at 20°C
pka
-1.0(at 25℃)
form 
Crystals
color 
White to almost white
Specific Gravity
1.406
Odor
Odorless
PH
6-8 (50g/l, H2O, 20℃)
PH Range
5 - 7
Water Solubility 
13.6 g/100 mL (20 ºC)
Merck 
14,9367
BRN 
605327
Stability:
Stable. Incompatible with strong acids, strong bases, strong oxidizing agents, metallic salts, proteins, hydrocarbons. May react violently with acrolein.
InChIKey
UMGDCJDMYOKAJW-UHFFFAOYSA-N
Substances Added to Food (formerly EAFUS)
THIOUREA--PROHIBITED
CAS DataBase Reference
62-56-6(CAS DataBase Reference)
FDA 21 CFR
189.190
EWG's Food Scores
5-8
FDA UNII
GYV9AM2QAG
NCI Dictionary of Cancer Terms
THU
NIST Chemistry Reference
Thiourea(62-56-6)
IARC
3 (Vol. Sup 7, 79) 2001
Proposition 65 List
Thiourea
EPA Substance Registry System
Thiourea (62-56-6)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS07,GHS08,GHS09
Signal word  Warning
Hazard statements  H302-H351-H361d-H411-H361
Precautionary statements  P280-P301+P312a-P405-P501a-P201-P273-P301+P312+P330-P308+P313-P391-P501
Hazard Codes  Xn,N,Xi
Risk Statements  22-40-51/53-63-43-38
Safety Statements  36/37-61
RIDADR  UN 2811 6.1/PG 3
WGK Germany  2
RTECS  YU2800000
Autoignition Temperature 440 °C Dust
TSCA  Yes
HazardClass  6.1
PackingGroup  III
HS Code  29309070
Toxicity LD50 orally in wild Norway rats: 1830 mg/kg (Dieke)
NFPA 704
0
2 0

Thiourea price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 30885 Thiourea ≥99.999% (metals basis) 62-56-6 5g $227 2020-08-18 Buy
Sigma-Aldrich PHR1758 Thiourea Pharmaceutical Secondary Standard; Certified Reference Material 62-56-6 200mg $256 2020-08-18 Buy
TCI Chemical T2835 Thiourea [for Biochemical Research] >99.0%(T) 62-56-6 5g $20 2020-06-24 Buy
TCI Chemical T2835 Thiourea [for Biochemical Research] >99.0%(T) 62-56-6 25g $40 2020-06-24 Buy
Alfa Aesar 036609 Thiourea, ACS 99% min. 62-56-6 50g $31 2020-06-24 Buy

Thiourea Chemical Properties,Uses,Production

Description

Thiourea appears as white crystal/powder, is combustible, and on contact with fire, gives off irritating or toxic fumes/gases. Thiourea is a reducing agent used primarily in the production of bleached recycled pulp. In addition, it is also effective in the bleaching of stone groundwood, pressurised groundwood. Thiourea undergoes decomposition on heating and produces toxic fumes of nitrogen oxides and sulphur oxides. It reacts violently with acrolein, strong acids, and strong oxidants. The main application of thiourea is in textile processing and also is commonly employed as a source of sulphide. Thiourea is a precursor to sulphide to produce metal sulphides, for example, mercury sulphide, upon reaction with the metal salt in aqueous solution. The industrial uses of thiourea include production of flame-retardant resins and vulcanisation accelerators. Thiourea is used as an auxiliary agent in diazo paper, light-sensitive photocopy paper, and almost all other types of copy paper. Thiourea is used in many industrial applications, including as a chemical intermediate or catalyst, in metal processing and plating, and in photoprocessing.

Chemical Properties

Thiourea consists of colorless, lustrous crystals or powder with a bitter taste.

Chemical Properties

white crystals or powder

Uses

The product is wildly used in pharmaceutical industry, agricultural, chemicals, metallurgical industry, petroleum and so on. It is also main material for producing thiourea dioxide(CH1N2O2S).

Uses

Chaotropic agent; strong denaturant. Increases solubility and recovery of proteins

Uses

Used in determination of bismuth.

Uses

In animal glue liquifiers and silver tarnish removers. Photographic fixing agent and to remove stains from negatives; manufacture of resins; vulcanization accelerator; a reagent for bismuth, selenite ions.

Uses

Thiourea is used in the manufacture of resins,as a vulcanization accelerator, and as aphotographic fixing agent and to removestains from negatives.

Uses

The most common uses for thiourea have been for the production of thiourea dioxide (30%), in leaching of gold and silver ores (25%), in diazo papers (15%), and as a catalyst in the synthesis of fumaric acid (10%) (IARC 2001). It has also been used in the production and modification of synthetic resins. Other uses of thiourea are as a photographic toning agent, in hair preparations, as a drycleaning agent, in the synthesis of pharmaceuticals and pesticides, in boiler-water treatment, and as a reagent for bismuth and selenite ions. It has also been used in textile and dyeing auxiliaries, in the production of industrial cleaning agents (e.g., for photographic tanks and metal surfaces in general), for engraving metal surfaces, as an isomerization catalyst in the conversion of maleic to fumaric acid, in copper-refining electrolysis, in electroplating, and as an antioxidant. Other uses have included as a vulcanization accelerator, an additive for slurry explosives,as a viscosity stabilizer for polymer solutions, and as a mobility buffer in petroleum extraction. It is also used as an ingredient of consumer silver polishes (HPD 2009), and has been used in the removal of mercury from wastewater by chlorine-alkali electrolysis (IARC 1974, 2001, WHO 2003).

Production Methods

Thiourea is formed by heating ammonium thiocyanate at 170 °C (338 °F). After about an hour, 25% conversion is achieved. With HCl, thiourea forms thiourea hydrochloride; with mercuric oxide, thiourea forms a salt; and with silver chloride, it forms a complex salt.

Definition

A colorless crystalline organic compound (the sulfur analog of urea). It is converted to the inorganic compound ammonium thiocyanate on heating. It is used as a sensitizer in photography and in medicine.

Definition

thiourea: A white crystalline solid,(NH2)2CS; r.d. 1.4; m.p. 182°C. It isused as a fixer in photography.

Definition

ChEBI: The simplest member of the thiourea class, consisting of urea with the oxygen atom substituted by sulfur.

General Description

White or off-white crystals or powder. Sinks and mixes with water.

Air & Water Reactions

Water soluble.

Reactivity Profile

Thiocarbamide is a white crystalline material or powder, toxic, carcinogenic. When heated to decomposition Thiocarbamide emits very toxic fumes of oxides of sulfur and oxides of nitrogen. Violent exothermic polymerization reaction with acrylaldehyde (acrolein) [MCA SD-85, 1961], violent decomposition of the reaction product with hydrogen peroxide and nitric acid [Bjorklund G. H. et al., Trans. R. Soc. Can.,1950, 44, p. 28], spontaneous explosion upon grinding with potassium chlorate [Soothill, D., Safety Management, 1992, 8(6), p. 11].

Hazard

A questionable carcinogen. May not be used in food products (FDA); skin irritant (allergenic).

Health Hazard

Poisonous inhaled or swallowed. Irritating to skin; may cause allergic skin eruptions.

Health Hazard

The acute oral toxicity of thiourea in mostanimals is of low order. The oral LD50 values reported in the literature show variation.Symptoms of chronic effects in rats includebone marrow depression and goiters. Administration of 32.8 mol of thiourea in chickembryos on day 17 of incubation resultedin the accumulation of parabronchial liquidin those embryos (Wittman et al. 1987). Theinvestigators have attributed such changes tothe toxic effects of thiourea, rather to than aretardation of pulmonary development.
Dedon and coworkers (1986) observed thepossible protective action of thiourea againstplatinum toxicity. Thiourea and other sulfur-containing nucleophiles have the ability tochelate and remove platinum from biochemical sites of toxicity.
Oral administration of thiourea resultedin tumors in the liver and thyroid in rats.It is carcinogenic to animals and has shownsufficient evidence.

Fire Hazard

Noncombustible solid. There is no report of any explosion resulting from reactions of thiourea. Small amounts of thiourea in contact with acrolein may polymerize acrolein, which is a highly exothermic reaction.

Agricultural Uses

Thiourea is a sulphur analogue of urea. It is a crystalline and colorless solid which is relatively insoluble in water. Thiourea, capable of breaking the dormancy of seeds, is used to stimulate seed germination. Seeds are soaked for less than 24 hours before planting.

Contact allergens

Thiourea is used as a cleaner agent for silver and cop- per, and as an antioxidant in diazo copy paper. It can induce (photo-) contact dermatitis.

Potential Exposure

Thiourea is used as rubber antiozonant, toning agent; corrosion inhibitor; and in pharmaceutical manufacture; in the manufacture of photosensitive papers; flame-retardant textile sizes; boiler water treatment. It is also used in photography; pesticide manufacture; in textile chemicals.

Carcinogenicity

Thiourea is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.

Shipping

UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN3077 Environmentally hazardous substances, solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required.

Purification Methods

Crystallise thiourea from absolute EtOH, MeOH, acetonitrile or water. Dry it under vacuum over H2SO4 at room temperature. [Beilstein 3 IV 342.]

Incompatibilities

Dust may form explosive mixture with air. Reacts violently with acrolein, strong acids (nitric acid). Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides.

Waste Disposal

Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal.

Thiourea Preparation Products And Raw materials

Raw materials

Hydrogen Sulfide Calcium cyanamide Calcium hydrosulfide Diazomethane Ammonium thiocyanate Hydrochloric acid Ethyl nitrite BARIUM SULFIDE Sulfuric acid Barium sulfate

Preparation Products

2-CHLORO-5-NITROTHIAZOLE 4-(4-CHLOROPHENYL)PYRIMIDINE-2-THIOL N-ACETYLTHIOUREA 2-AMINO-6-METHYL-PYRIMIDINE-4-THIOL 2-Amino-((1-carboxy-1-methyl ethoxy)imino)-4-thiazoleacetic acid 6-AMINO-2-METHYLTHIO-3-METHYLURACIL 4,6-Dimethyl-2-methylmercapyrimidine 2-Amino-4-methyl-5-acetylthiazole ETHYL 2-CHLORO-4-METHYL-1,3-THIAZOLE-5-CARBOXYLATE Ethyl 4-amino-2-(ethylthio)-5-pyrimidinecarboxylate 9,10-DIMETHYLANTHRACENE 4-AMINO-2-MERCAPTOPYRIMIDINE-5-CARBONITRILE 4,6-DIMETHYL-2-THIOPYRIMIDINE Ethyl 2-amino-4-phenyl-5-thiazolecarboxylate Oxfendazole AMICARTHIAZOL ETHYL 2-(ETHYLTHIO)-4-HYDROXYPYRIMIDINE-5-CARBOXYLATE Pseudothiohydantoin Ethyl 2-amino-4-methylthiazole-5-carboxylate 2-Thiobarbituric acid 2-(2-Aminothiazole-4-yl)-2-methoxyiminoacetic acid 2-Amino-5-methylthiazole Isobutylmercaptan Ethyl 2-(2-aminothiazole-4-yl)-2-hydroxyiminoacetate METHYL 2-CHLORO-4-THIAZOLECARBOXYLATE 2-Amino-2-thiazoline hydrochloride 4-HYDROXY-6-MERCAPTOPYRAZOLO[3,4-D]PYRIMIDINE 4,6-DIAMINO-2-MERCAPTOPYRIMIDINE Methylene dithiocyanate 1-Mercaptooctane 4-AMINO-2-(METHYLTHIO)-6-PYRIMIDINOL 4-Amino-6-hydroxy-2-mercaptopyrimidine monohydrate Guanidineacetic acid Prazosin 2-Aminothiazol-4-acetic acid 5-METHOXY-2-SULFANYL-4-PYRIMIDINOL Cyclohexyl mercaptan 2-thiouracil 1-Dodecanethiol 5-ETHYL-2-THIOURACIL

Thiourea Suppliers

Global( 435)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Hefei TNJ Chemical Industry Co.,Ltd. 		0551-65418671
 0551-65418697 sales@tnjchem.com CHINA 37442 58
Shandong chuangyingchemical Co., Ltd.
18853181302
 sale@chuangyingchem.com CHINA 5917 58
Qingdao Trust Agri Chemical Co.,Ltd
13573296305 008613573296305
 0532-87927000 aroma@qdtrustagri.com CHINA 192 58
Henan DaKen Chemical CO.,LTD. 		+86-371-55531817
 info@dakenchem.com CHINA 21710 58
Henan Tianfu Chemical Co.,Ltd. 		0371-55170693
 0371-55170693 info@tianfuchem.com CHINA 22617 55
Hangzhou FandaChem Co.,Ltd. 		0086 158 5814 5714 (Mobile
 +86-571-56059825 fandachem@gmail.com CHINA 8464 55
Hefei TNJ Chemical Industry Co.,Ltd. 		86-0551-65418684 18949823763
 86-0551-65418684 info@tnjchem.com China 2799 55
Hebei Chisure Biotechnology Co.LTD 		13292891350 +86 13292890173
 luna@speedgainpharma.com CHINA 1011 58
career henan chemical co 		+86-371-86658258
 sales@coreychem.com CHINA 30021 58
Hubei Jusheng Technology Co.,Ltd. 		86-18871470254
 027-59599243 linda@hubeijusheng.com CHINA 28230 58

Related articles

View Lastest Price from Thiourea manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2019-04-29 Thiocarbamide
62-56-6 		US $10.00 / KG 1KG 99% 500tons/month Hebei Chisure Biotechnology Co.LTD
2020-12-04 Thiourea
62-56-6 		US $1.00 / KG 1000KG 99% 2000tons per month qingdao trust agri chemical co.,ltd
2020-11-30 Thiourea
62-56-6 		US $1.50 / Kg/Bag 1T 99%;98.8%;98% 20 tons Hebei Dongdu Import and Export Co. LTD

Thiourea Spectrum

Thiocarbamide(62-56-6) MSThiocarbamide(62-56-6) IR2Thiocarbamide(62-56-6) IR1

62-56-6(Thiourea)Related Search:

Urea N-(fluoresceinyl)-N'-(1-(6-(3-mercapto-2-benzyl-1-oxopropyl)amino)-1-hexyl)thiocarbamide THIOUREA = THIOCARBAMIDE Thiocarbohydrazide Thiophanate-methyl fluorescein phosphatidylethanolamine thiocarbamide Allylthiourea Dithizone 1-(2-Chlorophenyl)-2-thiourea 1-PHENYL-2-THIOUREA Ethylene thiourea 1,3-Diphenyl-2-thiourea 2-Thiohydantoin 1,3-DIETHYL-2-THIOCARBAMIDE 1-(2-NAPHTHYL)-2-THIOUREA N-METHYLTHIOUREA 4-METHYL-5-(TRIFLUOROMETHYL)-1,2,4-TRIAZOLIN-3(2H)-THIONE 1-BENZYL-3-METHYL-2-THIOUREA
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