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2-Bromo-5-amino-4-picoline

2-Bromo-5-amino-4-picoline structure

CAS No.: 156118-16-0

Chemical Name:: 2-Bromo-5-amino-4-picoline

Synonyms: 3-Amino-6-bromo-4-methylpyridine;6-BroMo-4-Methyl-pyridin-3-ylaMine;2-Bromo-5-amino-4-picoline;2-BROMO-5-AMINO-4-PICOLIN...;6-Bromo-4-methyl-3-pyridinamine;5-Amino-2-bromo-4-methylpyridine;2-Bromo-5-amino-4-methylpyridine;3-Pyridinamine, 6-bromo-4-methyl-;5-Amino-2-bromo-4-methylpyridine,98%;2-BROMO-5-AMINO-4-PICOLINE ISO 9001：2015 REACH

CBNumber:: CB11076065

Molecular Formula:: C6H7BrN2

Molecular Weight:: 187.04

MDL Number:: MFCD08277280

MOL File:: 156118-16-0.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-09-12 18:48:34

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2-Bromo-5-amino-4-picoline Properties

Boiling point	306.9±37.0 °C(Predicted)
Density	1.593±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
pka	2.38±0.18(Predicted)
form	Powder
color	Brown
InChI	1S/C6H7BrN2/c1-4-2-6(7)9-3-5(4)8/h2-3H,8H2,1H3
InChIKey	MVDBPMJQCXZKRB-UHFFFAOYSA-N
SMILES	Brc1ncc(c(c1)C)N
CAS DataBase Reference	156118-16-0
UNSPSC Code	12352200
NACRES	NA.21

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H312-H315-H319-H332-H335

Precautionary statements

P261-P280-P304+P340-P305+P351+P338-P405-P501a

RIDADR

UN2811

HazardClass

6.1

HS Code

2933399990

Storage Class

11 - Combustible Solids

Hazard Classifications

Acute Tox. 4 Oral

NFPA 704

	0
2		0

2-Bromo-5-amino-4-picoline price More Price(63)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	PHB00200	2-Bromo-5-amino-4-picoline Aldrich^CPR	156118-16-0	1 g	$77.9	2026-04-30	Buy
Usbiological	231593	3-Amino-6-bromo-4-methylpyridine 98+% (GC) ≥98%(GC)	156118-16-0	1g	$192	2026-06-03	Buy
Usbiological	231593	3-Amino-6-bromo-4-methylpyridine 98+% (GC) ≥98%(GC)	156118-16-0	5g	$276	2026-06-03	Buy
Usbiological	231593	3-Amino-6-bromo-4-methylpyridine 98+% (GC) ≥98%(GC)	156118-16-0	25g	$715	2026-06-03	Buy
Apolloscientific	OR315200	6-Bromo-4-methylpyridin-3-amine >98%	156118-16-0	5g	$21	2026-06-04	Buy

Product number	Packaging	Price	Buy
PHB00200	1 g	$77.9	Buy
231593	1g	$192	Buy
231593	5g	$276	Buy
231593	25g	$715	Buy
OR315200	5g	$21	Buy

2-Bromo-5-amino-4-picoline Chemical Properties, Uses, Production

Synthesis

23056-47-5

156118-16-0

A suspension of 2-bromo-4-methyl-5-nitropyridine (XIV) (200 g, 921 mmol, 1.00 eq.) was formed with NH4Cl (240 g, 4.49 mol, 4.87 eq.) in EtOH (3.50 L) and water (150 mL). The mixture was heated to 50 °C with stirring. Subsequently, Fe (120 g, 2.15 mol, 2.33 eq.) and HCl (10.2 g, 279 mmol, 0.30 eq.) were added to the mixture. The suspension was heated to 80 °C and kept for 3 hours. After completion of the reaction, the mixture was cooled to 25 °C and filtered through a diatomaceous earth plug. The filtrate was concentrated under reduced pressure to give a residue. The residue was dissolved in EtOAc (1L x 3) and washed with brine. The organic layer was dried with sodium sulfate, filtered and concentrated under reduced pressure to give 6-bromo-4-methylpyridin-3-amine (XV) as a brown solid (167.9 g, 898 mmol, 97.4% yield), which could be used for the next reaction without further purification.1H NMR (CDCl3,400 MHz) δ ppm 2.15 (s, 3H), 3.44 (br s 2H), 7.14 (s, 1H), 7.78 (s, 1H); ESIMS m/z 186.8 ([M + H]+).

References

[1] Patent: WO2017/23975, 2017, A1. Location in patent: Paragraph 0610; 0611
[2] Patent: WO2017/24026, 2017, A1. Location in patent: Paragraph 0614; 0615
[3] Bioorganic and Medicinal Chemistry Letters, 2016, vol. 26, # 15, p. 3441 - 3446
[4] Bioorganic and Medicinal Chemistry Letters, 2015, vol. 25, # 22, p. 5258 - 5264
[5] Bioorganic and Medicinal Chemistry, 2007, vol. 15, # 6, p. 2441 - 2452

2-Bromo-5-amino-4-picoline synthesis

Synthesis of 2-Bromo-5-amino-4-picoline from 2-Bromo-5-nitro-4-picoline

2-Bromo-5-amino-4-picoline Preparation Products And Raw materials

Raw materials

2-Bromo-5-nitro-4-picoline Ammonium chloride Hydrochloric acid Water Iron

Ethanol

1of2

Preparation Products

2-Bromo-5-amino-4-picoline Suppliers

Global Suppliers ( 163)

Supplier	Tel	Email	Country	ProdList	Advantage
Liaoning Tianhua Chemical Co., Ltd.	0418-6530555 2855550		China	338	69
Capot Chemical Co., Ltd	+86 (0) 571 85 58 67 18		China	18187	66
Jia Xing Isenchem Co.,Ltd	0573-85285100 18627885956	isenchem@163.com	China	9388	66
Pure Chemistry Scientific Inc.	001-857-928-2050 or 1-888-588-9418	sales@chemreagents.com	United States	10174	62
Nanjing Chemlin Chemical Co., Ltd	025-83697070 13770331960	info@chemlin.com.cn	China	16307	64
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42917	64
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32273	50
Shenyang Comrade Chemical Co., Ltd.	+86(24) 31938773(O)	sales@co-chem.com	China	225	62
Tianjin Jinyuda Chemical Co., Ltd.	022-58013646 13011382049	sales@jinyudachem.com	China	1976	55
Shanghai ZaiQi Bio-Tech Co., Ltd.	021-54824098, 021-37212705 021-37212706, 13391256916	sales@chemzq.com	China	569	55

Supplier	Advantage
Liaoning Tianhua Chemical Co., Ltd.	69
Capot Chemical Co., Ltd	66
Jia Xing Isenchem Co.,Ltd	66
Pure Chemistry Scientific Inc.	62
Nanjing Chemlin Chemical Co., Ltd	64
Shanghai Hanhong Scientific Co.,Ltd.	64
Chemsky（shanghai）International Co.,Ltd.	50
Shenyang Comrade Chemical Co., Ltd.	62
Tianjin Jinyuda Chemical Co., Ltd.	55
Shanghai ZaiQi Bio-Tech Co., Ltd.	55

View Latest Price from 2-Bromo-5-amino-4-picoline manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-02	2-BROMO-5-AMINO-4-PICOLINE 156118-16-0	$5.00	1KG	98%		Henan Fengda Chemical Co., Ltd
2026-06-30	2-BROMO-5-AMINO-4-PICOLINE 156118-16-0		1KG	98.0%	10000KGS	Shaanxi Dideu New Materials Co. Ltd
2019-09-02	2-BROMO-5-AMINO-4-PICOLINE 156118-16-0	$1.00	1KG	98%	1kg; 10kg; 100kg	Career Henan Chemical Co

2-BROMO-5-AMINO-4-PICOLINE
156118-16-0
$5.00
98%
Henan Fengda Chemical Co., Ltd

2-BROMO-5-AMINO-4-PICOLINE
156118-16-0
98.0%
Shaanxi Dideu New Materials Co. Ltd

2-BROMO-5-AMINO-4-PICOLINE
156118-16-0
$1.00
98%
Career Henan Chemical Co

2-Bromo-5-amino-4-picoline Spectrum

2-BROMO-5-AMINO-4-PICOLINE(156118-16-0)¹HNMR

156118-16-0 (2-Bromo-5-amino-4-picoline) Related Search:

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5-Amino-2-bromo-4-methylpyridine 3-Pyridinamine, 6-bromo-4-methyl- 6-Bromo-4-methyl-3-pyridinamine 2-BROMO-5-AMINO-4-PICOLIN... 2-BROMO-5-AMINO-4-PICOLINE ISO 9001：2015 REACH 5-Amino-2-bromo-4-methylpyridine,98% 2-Bromo-5-amino-4-methylpyridine 6-BroMo-4-Methyl-pyridin-3-ylaMine 5-Amino-2-bromo-4-methylpyridine (3-Amino-6-bromo-4-methylpyridine) 2-Bromo-5-amino-4-picoline