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Nemorubicin

Nemorubicin structure

CAS No.: 108852-90-0

Chemical Name:: Nemorubicin

Synonyms: MMRDX;DMM Dox;FCE 23762;PNU 152243;Nemorubicin;PNU-152243A;Nemorubicina;NeMorubincine;-Dichlorobenzophenone;Nemorubicin (PNU 152243)

CBNumber:: CB11179292

Molecular Formula:: C32H37NO13

Molecular Weight:: 643.64

MDL Number:: MFCD00871079

MOL File:: 108852-90-0.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-27 23:05:51

Product description	Number	Pack Size	Price
Nemorubicin 97.01%	CS-2020	5mg	$162
Nemorubicin	BN180615	1mg	$634.92
Nemorubicin	BN180615	2mg	$1088.44
Nemorubicin 97.01%	CS-2020	10mg	$271
Nemorubicin	BN180615	5mg	$1451.2

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Nemorubicin Properties

Boiling point	852.2±65.0 °C(Predicted)
Density	1.55±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO:60.0(Max Conc. mg/mL);101.0(Max Conc. mM)
pka	7.35±0.60(Predicted)
form	Powder
color	Orange to reddish brown
InChIKey	CTMCWCONSULRHO-UZGLGGDGNA-N
SMILES	C12C[C@@](C[C@]([H])(O[C@@H]3O[C@H]([C@@H](O)[C@@H](N4CCO[C@H](OC)C4)C3)C)C=1C(O)=C1C(=O)C3=C(OC)C=CC=C3C(=O)C1=C2O)(O)C(=O)CO \|&1:2,4,7,9,10,12,17,r\|
FDA UNII	7618O47BQM

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P261-P305+P351+P338

Nemorubicin price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-2020	Nemorubicin 97.01%	108852-90-0	5mg	$162	2026-06-04	Buy
Biosynth	BN180615	Nemorubicin	108852-90-0	1mg	$634.92	2026-06-04	Buy
Biosynth	BN180615	Nemorubicin	108852-90-0	2mg	$1088.44	2026-06-04	Buy
ChemScene	CS-2020	Nemorubicin 97.01%	108852-90-0	10mg	$271	2026-06-04	Buy
Biosynth	BN180615	Nemorubicin	108852-90-0	5mg	$1451.2	2026-06-04	Buy

Product number	Packaging	Price	Buy
CS-2020	5mg	$162	Buy
BN180615	1mg	$634.92	Buy
BN180615	2mg	$1088.44	Buy
CS-2020	10mg	$271	Buy
BN180615	5mg	$1451.2	Buy

Nemorubicin Chemical Properties,Uses,Production

Uses

Nemorubicin is a doxorubicin derivative that differs significantly from its parent drug in terms of spectrum of antitumor activity, metabolism and toxicity profile. The drug is active on tumors resistant to alkylating agents, topoisomerase II inhibitors and platinum derivatives. It works primarily through topoisomerase I inhibition. Of note, Nemorubicin is active in cells with upregulation of the nucleotide excision repair (NER) pathway, where current therapies fail. Nemorubicin is biotransformed in the liver into cytotoxic metabolites that may further contribute to render this drug highly active against primary liver tumors or liver metastases.

Definition

ChEBI: Nemorubicin is a member of morpholines, an anthracycline antibiotic, a primary alpha-hydroxy ketone and a tertiary alpha-hydroxy ketone. It is functionally related to a doxorubicin.

in vivo

Nemorubicin is converted to PNU-159682 by human liver cytochrome P450 (CYP) 3A4 in rat, mouse, and dog liver microsomes^[2]. Nemorubicin (60 μg/kg) induces sifnificant tumor growth delay in scid mice bearing 9L/3A4 tumors, but shows no obvious effect on the tumor growth delay of 9L tumors in mice by i.v. or intratumoral injection (i.t.). Nemorubicin (40 μg/kg, i.p.) exhibits no antitumor activity and no host toxicity in mice bearing 9L/3A4 tumors^[4].

target

cancer

Nemorubicin Preparation Products And Raw materials

Raw materials

Preparation Products

Nemorubicin Suppliers

Global( 89)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hangzhou Benoy Chemical Co., Ltd	+8617342059697	sales@benoychem.com	China	315	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
AB PharmaTech,LLC	323-480-4688	sales@acrospharmatech.com	United States	989	55
Jurong Coupling Biotechnology Co., Ltd.	13656108824	coupling278191416@hotmail.com	CHINA	184	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29792	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
Baoji Guokang Healthchem Co., Ltd.	+86-0917-3909592 +86-13892490616	gksales1@gk-bio.com	China	9067	58
XI'AN TIANGUANGYUAN BIOTECH CO., LTD.	+86-029-86333380 +86-18829239519	sales06@tgybio.com	China	898	58
BOC Sciences	16314854226; +16314854226	inquiry@bocsci.com	United States	19853	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6391	58

Supplier	Advantage
Hangzhou Benoy Chemical Co., Ltd	58
ATK CHEMICAL COMPANY LIMITED	60
AB PharmaTech,LLC	55
Jurong Coupling Biotechnology Co., Ltd.	58
career henan chemical co	58
TargetMol Chemicals Inc.	58
Baoji Guokang Healthchem Co., Ltd.	58
XI'AN TIANGUANGYUAN BIOTECH CO., LTD.	58
BOC Sciences	58
InvivoChem	58

Unlocking the Potential of Nemorubicin: Insights into Its Mechanism, Applications, and Storage
Nemorubicin, a doxorubicin derivative, is a DNA-intercalator, topoisomerase and RNA synthesis inhibitor that used for the trea....
Dec 13，2024

Nemorubicin:Metabolism and Pharmacokinetics, Cytotoxic Activity And Toxicity Studies
Nemorubicin is a member of the structural group of morpholinyl anthracyclines whose lead compounds were originally obtained by....
Feb 21，2023

View Lastest Price from Nemorubicin manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-05-11	Nemorubicin 108852-90-0	$51.00-197.00		97.79%	10g	TargetMol Chemicals Inc.
2021-07-13	Nemorubicin 108852-90-0	$10.00-15.00	1KG	99%+ HPLC		Zhuozhou Wenxi import and Export Co., Ltd
2021-07-09	Nemorubicin 108852-90-0	$10.00-15.00	1KG	99%+ HPLC		Zhuozhou Wenxi import and Export Co., Ltd

Nemorubicin
108852-90-0
$51.00-197.00
97.79%
TargetMol Chemicals Inc.

Nemorubicin
108852-90-0
$10.00-15.00
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

Nemorubicin
108852-90-0
$10.00-15.00
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

Nemorubicin Spectrum

Nemorubicin(108852-90-0)¹HNMR

108852-90-0(Nemorubicin)Related Search:

1,8-Dihydroxyanthraquinone Adriamycin Doxorubicinone Nemorubicin Idarubicin

Chrysophanic acid 2-Ethyl anthraquinone DIETHANOL PROPANOLAMINE N,N-BIS(2-HYDROXYETHYL)ISOPROPANOLAMINE 1,5-DIHYDROXYANTHRAQUINONE

2,4-DIMETHYL-2'-METHOXYBENZOPHENONE 2,4-DIMETHYL-3'-METHOXYBENZOPHENONE 2,5-DIMETHYL-3'-METHOXYBENZOPHENONE N-ETHYL-TETRAHYDRO-2H-PYRAN-4-AMINE 14-Hydroxy Carminomycin

2-METHOXY-3'-METHYLBENZOPHENONE ISLANDICIN Feudomycin A

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Nemorubicin 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-10-2,3,6-trideoxy-3-(2S)-2-methoxy-4-morpholinyl-.alpha.-L-lyxo-hexopyranosyloxy-, (8S,10S)- methoxy-morpholynil-doxorubicin NeMorubincine (1S,3S)-3-Glycoloyl-1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1-naphthacenyl 2,3,6-trideoxy-3-[(S)-2-methoxymorpholino]-alpha-L-lyxo-hexopyranoside DMM Dox FCE 23762 Methoxymorpholinyldoxorubicin MMRDX (1S,3S)-3-Glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 2,3,6-trideoxy-3-[(2S)-2-methoxy-4-morpholinyl]-α-L-lyxo-hexopyranoside PNU152243A; PNU-152243A; PNU 152243A; NEMORUBICIN; METHOXYMORPHOLINYL-DOXORUBICIN PNU 152243 PNU-152243A Nemorubicin (PNU 152243) 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-[[2,3,6-trideoxy-3-[(2S)-2-methoxy-4-morpholinyl]-α-L-lyxo-hexopyranosyl]oxy]-, (8S,10S)- 5,12-Naphthacenedione,7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-[[2,3,6-trideoxy-3-[(2S)-2-methoxy-4-morpholinyl]-a-L-lyxo-hexopyranosyl]oxy]-, (8S,10S)- FCE 23762,FCE-23762,PNU-152243,PNU152243,inhibit,Methoxymorpholinyl doxorubicin,Inhibitor,Nemorubicin,FCE23762 Nemorubicina -Dichlorobenzophenone (8S,10S)-6,8,11-Trihydroxy-10-(((2R,4S,5S,6S)-5-hydroxy-4-((S)-2-methoxymorpholino)-6-methyltetrahydro-2H-pyran-2-yl)oxy)-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione 108852-90-0 108852-90-1 ≧99%