Tussilagone
- CAS No.
- 104012-37-5
- Chemical Name:
- Tussilagone
- Synonyms
- L 652469;Tussilagone;Tussilagone-RM;Tussilagone, 98%, from Farfarae Flos;(1S,3aR,5R,7S,7aS)-1-((R)-1-Acetoxyethyl)-7-isopropyl-4-methylene-2-oxooctahydro-1H-inden-5-yl (E)-3-methylpent-2-enoate;(1R,3aR,5R,7S,7aS)-1-(1-acetyloxyethyl)-4-methylidene-2-oxo-7-propan-2-yl-3,3a,5,6,7,7a-hexahydro-1H-inden-5-yl](E)-3-methylpent-2-enoate;2-Pentenoic acid, 3-methyl-, (1S,3aR,5R,7S,7aS)-1-[(1R)-1-(acetyloxy)ethyl]octahydro-4-methylene-7-(1-methylethyl)-2-oxo-1H-inden-5-yl ester, (2E)-
- CBNumber:
- CB11253147
- Molecular Formula:
- C23H34O5
- Molecular Weight:
- 390.51
- MDL Number:
- MFCD32004666
- MOL File:
- 104012-37-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Tussilagone | 301089 | 10mg | $453 |
| TUSSILAGONE 95.00% | HBL0000398 | 5MG | $503.69 |
| Tussilagone >98%,Standard References Grade | orb105062 | 20mg | $569.5 |
| Tussilagone 98% | 74121 | 20mg | $600 |
| Tussilagone 98% | orb259543 | 100mg | $923.1 |
| More product size | |||
| Boiling point | 471.3±35.0 °C(Predicted) |
|---|---|
| Density | 1.07±0.1 g/cm3 (20 ºC 760 Torr) |
| storage temp. | 2-8°C |
| form | Solid |
| color | White to off-white |
| InChIKey | CFUPNMDNSQIWBB-UUVDBSHOSA-N |
| SMILES | C(O[C@@H]1C[C@@H](C(C)C)[C@@]2([H])[C@]([H])(C1=C)CC(=O)[C@@H]2[C@H](OC(C)=O)C)(=O)/C=C(\C)/CC |
| FDA UNII | 95N0GBB2SX |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Safety Statements | 24/25 |
|---|---|
| WGK Germany | WGK 3 |
| HS Code | 29389090 |
| Storage Class | 11 - Combustible Solids |
Tussilagone price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 301089 | Tussilagone | 104012-37-5 | 10mg | $453 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HBL0000398 | TUSSILAGONE 95.00% | 104012-37-5 | 5MG | $503.69 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb105062 | Tussilagone >98%,Standard References Grade | 104012-37-5 | 20mg | $569.5 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 74121 | Tussilagone 98% | 104012-37-5 | 20mg | $600 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb259543 | Tussilagone 98% | 104012-37-5 | 100mg | $923.1 | 2021-12-16 | Buy |
Tussilagone Chemical Properties,Uses,Production
Chemical Properties
White crystalline powder, soluble in ether, chloroform, ethyl acetate, methanol, insoluble in water, derived from the flower bud of Asteraceae Tussilago farfara, Senecio kleinia Less root.
Uses
Tussilagone, a major active component in Tussilago farfara, has anti-inflammatory effect. Tussilagone ameliorates inflammatory responses in dextran sulphate sodium-induced murine colitis. Tussilagone inhibits the inflammatory response and improves survival in cecal ligation and puncture (CLP)-induced septic mice[1][2].
Biological Activity
Tussilagone, the main active ingredient of Tussilago farfara, has anti-inflammatory properties. It ameliorates the inflammatory response of dextran sulfate sodium-induced colitis in mice.
in vivo
Tussilagone administration (1 mg/kg and 10 mg/kg) produced decreased mortality and lung injury in CLP-activated septic mice. Augmented expression of cyclooxygenase (COX)-2 and TNF-α in pulmonary alveolar macrophages of septic mice were attenuated by tussilagone administration.
References
[1] Cheon HJ, et al. Tussilagone, a major active component in Tussilago farfara, ameliorates inflammatory responses in dextran sulphate sodium-induced murine colitis. Chem Biol Interact. 2018 Oct 1;294:74-80. DOI:10.1016/j.cbi.2018.08.022
[2] Kim YK, et al. Tussilagone Inhibits the Inflammatory Response and Improves Survival in CLP-Induced SepticMice. Int J Mol Sci. 2017 Dec 18;18(12). pii: E2744. DOI:10.3390/ijms18122744
Tussilagone Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| Chengdu Greenpure Biopharma CO.,Ltd | 18283602253; +8618283602253 | jancyzheng@gcgreenpure.com | China | 954 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29819 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 3751 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 | sales@chemnorm.com | CHINA | 2935 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32467 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10236 | 58 |
| HONG KONG IPURE BIOLOGY CO.,LIMITED | 86 18062405514 18062405514 | ada@ipurechemical.com | CHINA | 3461 | 58 |
View Lastest Price from Tussilagone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-22 | Tussilagone
104012-37-5
|
US $51.00-179.00 / mg | 99.63% | 10g | TargetMol Chemicals Inc. | ||
 |
2023-02-24 | Tussilagone
104012-37-5
|
US $0.00 / mg | 5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. | |
 |
2019-07-06 | Tussilagone
104012-37-5
|
US $1.00 / KG | 1KG | 99% | Customized | Career Henan Chemical Co |
-
- Tussilagone
104012-37-5
- US $51.00-179.00 / mg
- 99.63%
- TargetMol Chemicals Inc.
-
- Tussilagone
104012-37-5
- US $0.00 / mg
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.
-
- Tussilagone
104012-37-5
- US $1.00 / KG
- 99%
- Career Henan Chemical Co
