ChemicalBook >> CAS DataBase List >>SB 204741
SB 204741
- CAS No.
- 152239-46-8
- Chemical Name:
- SB 204741
- Synonyms
- SB 204741;1-(1-methyl-5-indolyl)-3-(3-methyl-5-isothiazolyl)urea;3-(3-METHYL-1,2-THIAZOL-5-YL)-1-(1-METHYLINDOL-5-YL)UREA;N-(1-METHYL-1H-5-INDOLYL)-N'-(3-METHYL-5-ISOTHIAZOLYL)UREA;1-(1-Methyl-1H-indol-5-yl)-3-(3-Methylisothiazol-5-yl)urea;N-(1-METHYL-1H-INDOLYL-5-YL)-N''-(3-METHYL-5-ISOTHIAZOLYL)UREA;Urea, N-(1-methyl-1H-indol-5-yl)-N'-(3-methyl-5-isothiazolyl)-;human,inhibit,SB204741,5-HT Receptor,Inhibitor,remodeling,Serotonin Receptor,selective,SB 204741,isoproterenol-induced,affinity,SB-204741,5-hydroxytryptamine Receptor,myocardial
- CBNumber:
- CB1207574
- Molecular Formula:
- C14H14N4OS
- Molecular Weight:
- 286.35
- MDL Number:
- MFCD00923644
- MOL File:
- 152239-46-8.mol
- MSDS File:
- SDS
Last updated:2023-09-20 16:43:00
| Melting point | >195°C (dec.) |
|---|---|
| storage temp. | 2-8°C |
| solubility | DMSO: ~18 mg/mL, soluble |
| form | solid |
| color | orange |
| Stability | Hygroscopic |
| FDA UNII | 9VHM49MS42 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
SB 204741 price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | S0693 | SB 204741 >98% (HPLC) | 152239-46-8 | 10mg | $214 | 2024-03-01 | Buy |
| Sigma-Aldrich | S0693 | SB 204741 >98% (HPLC) | 152239-46-8 | 50mg | $858 | 2024-03-01 | Buy |
| Tocris | 1372 | SB 204741 ≥99%(HPLC) | 152239-46-8 | 10 | $162 | 2021-12-16 | Buy |
| Tocris | 1372 | SB 204741 ≥99%(HPLC) | 152239-46-8 | 50 | $682 | 2021-12-16 | Buy |
| TRC | S155025 | SB 204741 | 152239-46-8 | 100mg | $120 | 2021-12-16 | Buy |
SB 204741 Chemical Properties,Uses,Production
Uses
SB 204741 is a potent, selective SR-2B antagonist.
Definition
ChEBI: 1-(1-methylindol-5-yl)-3-(3-methyl-1,2-thiazol-5-yl)urea is a member of ther class of ureas that is urea in which a hydrogen attached to one of the nitrogens has been replaced by an N-methylindol-5-yl group, while a hydrogen attached to the other nitrogen has been replaced by a 3-methyl-1,2-thiazol-5-yl group. It is a potent and selective antagonist for the 5-hydroxytryptamine 2B (5-HT2B) receptor. It has a role as a receptor modulator and a serotonergic antagonist. It is a member of ureas, a member of indoles and a member of 1,2-thiazoles.
Biological Activity
Potent and selective 5-HT 2B receptor antagonist (pA 2 = 7.95). Displays ≥ 135-fold selectivity over 5-HT 2C (pK i = 5.82), 5-HT 2A (pK i < 5.2), 5-HT 1A , 1D , 1E , 5-HT 3 and 5-HT 4 receptors.
storage
Room temperature
SB 204741 Preparation Products And Raw materials
Raw materials
Preparation Products
SB 204741 Suppliers
Global( 67)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3136 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131980 | 58 |
| Chengdu Saint - Kay Biotechnology Co., Ltd. | 028-85157043 15882256948 | 676046971@qq.com | China | 4394 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12990 | 57 |
152239-46-8(SB 204741)Related Search:
SB 204741
N-(1-METHYL-1H-5-INDOLYL)-N'-(3-METHYL-5-ISOTHIAZOLYL)UREA
N-(1-METHYL-1H-INDOLYL-5-YL)-N''-(3-METHYL-5-ISOTHIAZOLYL)UREA
1-(1-Methyl-1H-indol-5-yl)-3-(3-Methylisothiazol-5-yl)urea
Urea, N-(1-methyl-1H-indol-5-yl)-N'-(3-methyl-5-isothiazolyl)-
1-(1-methyl-5-indolyl)-3-(3-methyl-5-isothiazolyl)urea
3-(3-METHYL-1,2-THIAZOL-5-YL)-1-(1-METHYLINDOL-5-YL)UREA
human,inhibit,SB204741,5-HT Receptor,Inhibitor,remodeling,Serotonin Receptor,selective,SB 204741,isoproterenol-induced,affinity,SB-204741,5-hydroxytryptamine Receptor,myocardial
152239-46-8
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