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XPhos Pd G1

CAS No.
1028206-56-5
Chemical Name:
XPhos Pd G1
Synonyms
XPhos Pd;XPhos Pd G1;XPhos precatalyst;XPhos Palladacycle;XPhos Palladacycle Gen. 1;[2-(2-Aminoethyl)phenyl](chloro)palladium-dicyclohexyl(2',4'...;Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl]palladium(II) ;[2-(2-AMinoethyl)phenyl](chloro)palladiuM-dicyclohexyl(2',4',6'-triisopropyl-2-biphenylyl)phosphine (1:1);Chloro(2-dicyclohexylphosphino-2′,4′,6′-triisopropyl-1,1′-biphenyl)[2-(2-aminoethyl)phenyl)]palladium(II);1028206-56-5 Palladium, [2-[2-(amino-κN)ethyl]phenyl-κC]chloro[dicyclohexyl[2',4',6'-tris(1-methylethyl)[1,1'-bip
CBNumber:
CB12129212
Molecular Formula:
C41H59ClNPPd
Molecular Weight:
738.77
MDL Number:
MFCD13194128
MOL File:
1028206-56-5.mol
MSDS File:
SDS
Last updated:2023-04-27 16:27:43

XPhos Pd G1 Properties

Melting point 205-210°C
form Powder
color white
CAS DataBase Reference 1028206-56-5

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335-H412
Precautionary statements  P261-P264-P271-P273-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38-52/53
Safety Statements  26-61
WGK Germany  3
HS Code  2843909000

XPhos Pd G1 price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 704954 Chloro(2-dicyclohexylphosphino-2′,4′,6′-triisopropyl-1,1′-biphenyl)[2-(2-aminoethyl)phenyl)]palladium(II) 1028206-56-5 1g $219 2024-03-01 Buy
Sigma-Aldrich 704954 Chloro(2-dicyclohexylphosphino-2′,4′,6′-triisopropyl-1,1′-biphenyl)[2-(2-aminoethyl)phenyl)]palladium(II) 1028206-56-5 25g $1556 2024-03-01 Buy
Strem Chemicals 46-0268 Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl] palladium(II) methyl-t-butylether adduct, min. 98% [XPhos Palladacycle Gen. 1] 1028206-56-5 1g $168 2021-12-16 Buy
Strem Chemicals 46-0268 Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl] palladium(II) methyl-t-butylether adduct, min. 98% [XPhos Palladacycle Gen. 1] 1028206-56-5 250mg $56 2021-12-16 Buy
Sigma-Aldrich 704954 Chloro(2-dicyclohexylphosphino-2′,4′,6′-triisopropyl-1,1′-biphenyl)[2-(2-aminoethyl)phenyl)]palladium(II) 1028206-56-5 250mg $46.26 2024-03-01 Buy
Product number Packaging Price Buy
704954 1g $219 Buy
704954 25g $1556 Buy
46-0268 1g $168 Buy
46-0268 250mg $56 Buy
704954 250mg $46.26 Buy

XPhos Pd G1 Chemical Properties,Uses,Production

Reaction

  1. Catalyst for cross-coupling reactions of electron-deficient anilines with aryl chlorides.
  2. Catalyst for rapid C-N bond-forming process at low catalyst loading.
  3. Catalyst for C-N cross-coupling reactions, at or below room temperature.
  4. Catalyst for the synthesis of tetracyclic indoles via intermolecular α-arylation of ketones.
  5. Catalyst for the cross-coupling of benzyl chlorides with cyclopropanol-derived ketone homoenolates
Reactions of 1028206-56-5_1
Reactions of 1028206-56-5_2
Reactions of 1028206-56-5_3

Uses

XPhos Pd G1 is used as androgen receptor modulator for treatment of disorders including prostate cancer.

Uses

Application Guide for Palladium Catalyzed Cross-Coupling Reactions

Catalyst used for:

  • Amination / cyclization reactions
  • C-N bond-forming reactions via packed-bed microreactors
  • Boration of aryl chlorides
  • Arylation of oxazole
  • Cross-coupling reactions

Preparation

XPhos Pd G1 is an insoluble solid that can be prepared by cross-coupling reactions of imidazole derivatives with dioxane. 

General Description

Material may contain up to 5% pentane

Physiological effects

XPhos Pd G1 has been shown to have anti-infectious properties against bacteria and viruses including influenza A, respiratory syncytial virus (RSV), human immunodeficiency virus (HIV), and hepatitis B. It also has metabolic effects on the body by reducing levels of pyridine compounds and increasing pyrazolyl concentrations in the blood stream. 

13078-80-3
14267-08-4
917-54-4
564483-18-7
1028206-56-5
Synthesis of XPhos Pd G1 from 2-Chlorophenethylamine and DICHLORO(N,N,N',N'-TETRAMETHYLETHYLENEDIAMINE)PALLADIUM(II) and Methyllithium and X-PHOS

XPhos Pd G1 Preparation Products And Raw materials

Global( 94)Suppliers
Supplier Tel Email Country ProdList Advantage
Wuhan Huahan Dingcheng New Material Technology Co., Ltd
+undefined-027-81388558 +undefined086-1878077615 huahandingcheng@sina.com China 342 58
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 15928 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
Shenzhen Nexconn Pharmatechs Ltd
+86-755-89396905 +86-15013857715 admin@nexconn.com China 10248 58
Nanjing Dolon Biotechnology Co.,Ltd.
18905173768 sales@dolonchem.com CHINA 2972 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Shaanxi Dideu Medichem Co. Ltd
+86-029-81138252 +86-18789408387 1057@dideu.com China 3537 58
Richest Group Ltd
18017061086 oled@richest-group.com CHINA 5601 58
QINGDAO KAIENSI INTERNATIONAL TRADE CO.,LTD.
+86-0532-8699-9256 +8615254267723 kaley@cnfdevelop.com China 1410 58

View Lastest Price from XPhos Pd G1 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl] palladium(II) methyl-t-butylether adduct /XPhos Pd G1 pictures 2021-06-11 Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl] palladium(II) methyl-t-butylether adduct /XPhos Pd G1
1028206-56-5
US $10.00-10.00 / g 1g 0.98 50kg Wuhan LPBchem Technology Co.,Ltd
XPhos Pd G1   pictures 2020-04-22 XPhos Pd G1
1028206-56-5
US $1.00 / KG 1KG 99% 20T Shaanxi Dideu Medichem Co. Ltd
	Chloro(2-dicyclohexylphosphino-2',4',6'-triisopropyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl]palladium(II) pictures 2020-01-08 Chloro(2-dicyclohexylphosphino-2',4',6'-triisopropyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl]palladium(II)
1028206-56-5
US $1.00 / g 1g Min98% HPLC g/kg/ton Career Henan Chemical Co
  • XPhos Pd G1   pictures
  • XPhos Pd G1
    1028206-56-5
  • US $1.00 / KG
  • 99%
  • Shaanxi Dideu Medichem Co. Ltd
XPhos Palladacycle XPhos precatalyst [2-(2-AMinoethyl)phenyl](chloro)palladiuM-dicyclohexyl(2',4',6'-triisopropyl-2-biphenylyl)phosphine (1:1) Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl]palladium(II) XPhos Pd G1 Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl] palladium(II) methyl-t-butylether adduct XPhos Pd Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl] palladium(II) methyl-t-butylether adduct, min. 98% [XPhos Palladacycle Gen. 1] Chloro(2-dicyclohexylphosphino-2′,4′,6′-triisopropyl-1,1′-biphenyl)[2-(2-aminoethyl)phenyl)]palladium(II) Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl] palladium(II) methyl-t-butylether adduct, min. 98% [XPhos Palladacycle] Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aMinoethyl)phenyl]palladiuM(II)Methyl-t-butyletheradduct,Min.98% Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl] palladium(II) methyl-t-butylether adduct, min. 98% Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aMinoethyl)phenyl] palladiuM(II) Methyl-t-butylether adduct,98% XPhos Palladacycle Palladium, [2-[2-(amino-KappaN)ethyl]phenyl-KappaC]chloro[dicyclohexyl[2',4',6'-tris(1-methylethyl)[1,1'-biphenyl]-2-yl]phosphine]-, (SP-4-4)- (SP-4-4)-[2-[2-(Amino-κN)ethyl]phenyl-κC]chloro[dicyclohexyl[2',4',6'-tris(1-methylethyl)[1,1'-biphenyl]-2-yl]phosphine]palladium Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aMinoethyl)phenyl] palladiuM(II) Methyl-t-butylether adduct [XPhos Palladacycle] Palladium, [2-[2-(amino-κN)ethyl]phenyl-κC]chloro[dicyclohexyl[2',4',6'-tris(1-methylethyl)[1,1'-biphenyl]-2-yl]phosphine]-, (SP-4-4)- XPhos Palladacycle Gen. 1 Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl] palladium(II) methyl-t-butylether adduct / XPhos Pd G1 [2-(2-Aminoethyl)phenyl](chloro)palladium-dicyclohexyl(2',4'... XPhos Pd G1 / Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl] palladium(II) methyl-t-butylether adduct 1028206-56-5 Palladium, [2-[2-(amino-κN)ethyl]phenyl-κC]chloro[dicyclohexyl[2',4',6'-tris(1-methylethyl)[1,1'-bip (SP-4-4)-2-[2-(Amino-KappaN)ethyl]phenyl-KappaC]chloro[dicyclohexyl[2',4',6'-tris(1-methylethyl)[1,1'-biphenyl]-2-yl]phosphine]-Palladium (SP-4-4)-2-[2-(Amino-KappaN)ethyl]phenyl-KappaC]chloro[dicyclohexyl[2',4',6'-tris(1-methylethyl)[1,1'-biphenyl]-2-yl]phosphine]-Palladium 1028206-56-5 C41H59ClNPPd Buchwald Ligands&Precatalysts Buchwald Precatalysts Series Pd