2-PiperidineMethanol, (2S)-
- CAS No.
- 41373-39-1
- Chemical Name:
- 2-PiperidineMethanol, (2S)-
- Synonyms
- (S)-Piperidin-2-ylMethanol;[(2S)-2-piperidyl]methanol;(S)-2-Piperidinemethanol;(2S)-2-Piperidinemethanol;2-PiperidineMethanol, (2S)-;[(2S)-piperidin-2-yl]methanol;(2S)-2-PiperidineMethanol HCl
- CBNumber:
- CB12639124
- Molecular Formula:
- C6H13NO
- Molecular Weight:
- 115.17
- MDL Number:
- MFCD11036291
- MOL File:
- 41373-39-1.mol
- MSDS File:
- SDS
| Melting point | 66-68 °C |
|---|---|
| Boiling point | 221.2±0.0 °C(Predicted) |
| Density | 0.951±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| pka | 15.08±0.10(Predicted) |
| Appearance | Colorless to light yellow <66°C Solid,>68°C Liquid |
| optical activity | 16.267° (C=0.01 g/ml, ETOH) |
| InChI | InChI=1S/C6H13NO/c8-5-6-3-1-2-4-7-6/h6-8H,1-5H2/t6-/m0/s1 |
| InChIKey | PRAYXGYYVXRDDW-LURJTMIESA-N |
| SMILES | N1CCCC[C@H]1CO |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|---|---|
| Signal word | Danger |
| Hazard statements | H314 |
| Precautionary statements | P260-P264-P280-P301+P330+P331-P303+P361+P353-P363-P304+P340-P310-P321-P305+P351+P338-P405-P501 |
| HS Code | 2933399990 |
2-PiperidineMethanol, (2S)- price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | P482660 | (2S)-2-Piperidinemethanol | 41373-39-1 | 500mg | $90 | 2021-12-16 | Buy |
| Apolloscientific | OR917897 | (2S)-Piperidin-2-ylmethanol 97% | 41373-39-1 | 1g | $145 | 2021-12-16 | Buy |
| ChemScene | CS-W001568 | (S)-Piperidin-2-ylmethanol | 41373-39-1 | 5g | $180 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CCH0031961 | ((S)-PIPERIDIN-2-YL)METHANOL 95.00% | 41373-39-1 | 1G | $253.05 | 2021-12-16 | Buy |
| Activate Scientific | AS14582 | (2S)-2-Piperidinemethanol HCl 97+% ee | 41373-39-1 | 5G | $260 | 2021-12-16 | Buy |
2-PiperidineMethanol, (2S)- Chemical Properties,Uses,Production
Synthesis
3105-95-1
41373-39-1
General procedure for the synthesis of (S)-piperidin-2-ylmethanol from L-2-piperidinic acid: BH3-DMS (62.0 mmol, 4.0 eq.) and BF3-Et2O (15.5 mmol, 1.0 eq.) were added to a solution of (2S)-piperidine-2-carboxylic acid (15.5 mmol, 1.0 eq.) in THF (50 ml) at 0 °C. The reaction mixture was refluxed for 14 hours. After completion of the reaction, the solvent was removed by concentration under reduced pressure, followed by slow dropwise addition of MeOH (40 ml) at 0 °C. Concentrated HCl (5 ml) was added to the mixture and refluxing was continued for 2 hours. The solvent was again concentrated to remove the solvent and the residue was stirred in a DCM solution of 10% isopropanol for 15 min and filtered. The filtrate was concentrated to dryness to give the white solid product (S)-piperidin-2-ylmethanol in 80% yield.
References
[1] Tetrahedron, 2013, vol. 69, # 51, p. 10876 - 10883
[2] Tetrahedron, 2013, vol. 69, # 30, p. 6129 - 6143
[3] Patent: US2010/173889, 2010, A1. Location in patent: Page/Page column 34
[4] Patent: US2009/253669, 2009, A1. Location in patent: Page/Page column 46-47
[5] Patent: US2009/264407, 2009, A1. Location in patent: Page/Page column 77
2-PiperidineMethanol, (2S)- Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 12419 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30230 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19987 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43340 | 58 |
| Sichuan Biosynce Pharmatech Co., Ltd. | +8619950309693 | diane@biosynce.com | China | 4871 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| Suzhou ARTK Medchem Co., Ltd. | +86-512-68323658 +86-18168183658 | sales1@artkmedchem.com | China | 39003 | 58 |
