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GSK2838232

CAS No.
1443461-21-9
Chemical Name:
GSK2838232
Synonyms
CS-947;EX-A202;GSK2838232;HIV Inhibitor GS2838232;GSK2838232(GSK2838232A);HIV Inhibitor GSK2838232;GSK-2838232A; GSK 2838232A;(3beta)-3-(3-Carboxy-3-methyl-1-oxobutoxy)-17-[(1R)-2-[[(3-chlorophenyl)methyl][2-(dimethylamino)ethyl]amino]-1-hydroxyethyl]-28-norlup-18-en-21-one;28-Norlup-18-en-21-one, 3-(3-carboxy-3-methyl-1-oxobutoxy)-17-[(1R)-2-[[(3-chlorophenyl)methyl][2-(dimethylamino)ethyl]amino]-1-hydroxyethyl]-, (3β)-
CBNumber:
CB12664173
Molecular Formula:
C48H73ClN2O6
Molecular Weight:
809.56
MDL Number:
MOL File:
1443461-21-9.mol
Last updated:2023-05-21 10:59:17

GSK2838232 Properties

Boiling point 817.1±65.0 °C(Predicted)
Density 1.17±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
form Powder
pka 4.48±0.28(Predicted)
FDA UNII G9C7884M8M

GSK2838232 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ApexBio Technology B5818 GSK2838232 1443461-21-9 5mg $551 2021-12-16 Buy
ApexBio Technology B5818 GSK2838232 1443461-21-9 10mg $788 2021-12-16 Buy
ApexBio Technology B5818 GSK2838232 1443461-21-9 50mg $2363 2021-12-16 Buy
ApexBio Technology B5818 GSK2838232 1443461-21-9 100mg $3308 2021-12-16 Buy
DC Chemicals DC7847 HIVInhibitorGSK2838232 >98% 1443461-21-9 1g $2500 2021-12-16 Buy
Product number Packaging Price Buy
B5818 5mg $551 Buy
B5818 10mg $788 Buy
B5818 50mg $2363 Buy
B5818 100mg $3308 Buy
DC7847 1g $2500 Buy

GSK2838232 Chemical Properties,Uses,Production

Biological Activity

gsk2838232 is an hiv-1 maturation inhibitor [1] [2].hiv-1 maturation inhibitors disrupt the cleavage of the hiv-1 gag protein immediate precursor by the enzyme hiv-1 protease. maturation inhibitors bind the gag protein, which leads to the formation of immature, noninfectious virus particles incapable of infecting other cells. also, maturation inhibitors inhibit hiv infections with resistance.gsk2838232 is a hiv-1 maturation inhibitor and is active against a broad range of isolates, including those resistant to bevirimat [1]. gsk2838232 was developed for the treatment of chronic hiv infection. a phase i study in hiv-negative individuals had been completed. single doses of 5, 10 or 20 mg gsk2838232 were used to evaluate the initial safety, tolerability, pharmacokinetics profile, and the effects of food and ritonavir on gsk2838232’s bioavailability and pharmacokinetics [2].

References

[1]. olender sa, taylor bs, wong m, et al. croi 2015: advances in antiretroviral therapy. croi 2015 highlights: antiretroviral therapy volume 23 issue 1 march/april 2015.
[2]. horn t, collins s. the antiretroviral pipeline. antiretrovirals, 2014 pipeline report.

GSK2838232 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 50)Suppliers
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ATK CHEMICAL COMPANY LIMITED
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Biochempartner
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Zhejiang J&C Biological Technology Co.,Limited
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InvivoChem
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ShenZhen Trendseen Biological Technology Co.,Ltd.
13417589054 trendseenbio@gmail.com China 11681 58
Aladdin Scientific
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Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131981 58
Shanghai Boyle Chemical Co., Ltd. sales@boylechem.com China 2923 55
HangZhou YuHao Chemical Technology Co., Ltd. 0571-82693216 info@yuhaochemical.com China 2031 58

View Lastest Price from GSK2838232 manufacturers

GSK2838232 (3beta)-3-(3-Carboxy-3-methyl-1-oxobutoxy)-17-[(1R)-2-[[(3-chlorophenyl)methyl][2-(dimethylamino)ethyl]amino]-1-hydroxyethyl]-28-norlup-18-en-21-one GSK-2838232A; GSK 2838232A CS-947 GSK2838232(GSK2838232A) HIV Inhibitor GS2838232 28-Norlup-18-en-21-one, 3-(3-carboxy-3-methyl-1-oxobutoxy)-17-[(1R)-2-[[(3-chlorophenyl)methyl][2-(dimethylamino)ethyl]amino]-1-hydroxyethyl]-, (3β)- EX-A202 HIV Inhibitor GSK2838232 1443461-21-9 C48H73ClN2O6