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FG-4592 interMediate

FG-4592 interMediate Structure
FG-4592 interMediate structure
CAS No.
1455091-10-7
Chemical Name:
FG-4592 interMediate
Synonyms
methyl 4-hydroxy-7-phenoxyisoquinoline-3-carboxylate;Roxadustat Impurity 13;3-Isoquinolinecarboxylic acid, 4-hydroxy-7-phenoxy-, methyl ester;ROXA-030;FG-4592 INT;FG4592 intermediates;FG-4592 interMediate;Roxadustat Impurity 4;Rosalistat impurity 4;Roxadustat Impurities3
CBNumber:
CB12730014
Molecular Formula:
C17H13NO4
Molecular Weight:
295.29
MDL Number:
MFCD29075436
MOL File:
1455091-10-7.mol
Last updated:2024-04-24 17:21:39
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FG-4592 interMediate Properties

Boiling point 534.7±45.0 °C(Predicted)
Density 1.320±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka 5.80±0.50(Predicted)
InChI InChI=1S/C17H13NO4/c1-21-17(20)15-16(19)14-8-7-13(9-11(14)10-18-15)22-12-5-3-2-4-6-12/h2-10,19H,1H3
InChIKey YTWDBRIDKWWANA-UHFFFAOYSA-N
SMILES C1C2=C(C=CC(OC3=CC=CC=C3)=C2)C(O)=C(C(OC)=O)N=1

FG-4592 interMediate price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC M327103 Methyl4-Hydroxy-7-phenoxyisoquinoline-3-carboxylate 1455091-10-7 500mg $165 2021-12-16 Buy
AK Scientific 6919EA Methyl4-hydroxy-7-phenoxyisoquinoline-3-carboxylate 1455091-10-7 5g $465 2021-12-16 Buy
Ambeed A110786 Methyl4-hydroxy-7-phenoxyisoquinoline-3-carboxylate 97% 1455091-10-7 25g $1073 2021-12-16 Buy
Ambeed A110786 Methyl4-hydroxy-7-phenoxyisoquinoline-3-carboxylate 97% 1455091-10-7 250mg $53 2021-12-16 Buy
Chemenu CM146104 methyl4-hydroxy-7-phenoxyisoquinoline-3-carboxylate 95+% 1455091-10-7 1g $102 2021-12-16 Buy
Product number Packaging Price Buy
M327103 500mg $165 Buy
6919EA 5g $465 Buy
A110786 25g $1073 Buy
A110786 250mg $53 Buy
CM146104 1g $102 Buy

FG-4592 interMediate Chemical Properties,Uses,Production

Uses

Methyl 4-Hydroxy-7-phenoxyisoquinoline-3-carboxylate is an intermediate of N-[(4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine (H948180), a hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitor used to increase white blood cell levels in blood and hematopoietic progenitor cells in bone marrow.

FG-4592 interMediate synthesis

1455091-04-9
2645-02-5
1455091-10-7
Synthesis of FG-4592 interMediate from methyl2-(chloromethyl)-4-phenoxybenzoate and Methyl 2-(4-methylphenylsulfonamido)acetate

FG-4592 interMediate Preparation Products And Raw materials

Raw materials

methyl2-(chloromethyl)-4-phenoxybenzoate 4-Bromo-2-methylbenzoic acid 1(3H)-Isobenzofuranone, 5-phenoxy- Methyl 2-(4-methylphenylsulfonamido)acetate 2-{[(methoxycarbonylmethyl)(toluene-4-sulfonyl)amino]methyl}-4-phenoxybenzoic acid methyl ester
BENZOIC ACID,4-BROMO-2-METHYL-,METHYL ESTER 5-Bromophthalide

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Preparation Products

4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinecarboxylic acid methyl ester methyl 2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate

FG-4592 interMediate Suppliers

Global( 192)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Famo Biotech Co Ltd 		+8618550473860 mayan@famobiotech.com China 509 58
Jiangsu Yutian pharmaceutical Co.,Ltd.
+undefined-0518-86098006 +undefined19851887368 lvan.hui@jsytsw.com China 80 58
Hangzhou ICH Biofarm Co., Ltd 		+86-0571-28186870; +undefined8613073685410 sales@ichemie.com China 985 58
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886 info@dakenam.com China 15954 58
Beijing Cooperate Pharmaceutical Co.,Ltd 		010-60279497 sales01@cooperate-pharm.com CHINA 1811 55
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21687 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32715 60
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Biochempartner 		0086-13720134139 candy@biochempartner.com CHINA 967 58
Jinan Finer Chemical Co., Ltd 		+86-531-88989536 +86-15508631887 sales@finerchem.com China 2966 58
Supplier Advantage
Shanghai Famo Biotech Co Ltd 		58
Jiangsu Yutian pharmaceutical Co.,Ltd.
58
Hangzhou ICH Biofarm Co., Ltd 		58
Shanghai Daken Advanced Materials Co.,Ltd 		58
Beijing Cooperate Pharmaceutical Co.,Ltd 		55
Henan Tianfu Chemical Co.,Ltd. 		55
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
Biochempartner 		58
Jinan Finer Chemical Co., Ltd 		58

View Lastest Price from FG-4592 interMediate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Hydroxy-7-phenoxy-3-isoquinolinecarboxylic acid methyl ester pictures 2024-06-04 4-Hydroxy-7-phenoxy-3-isoquinolinecarboxylic acid methyl ester
1455091-10-7
 US $0.00-0.00 / kg 1kg ＞98% by HPLC 10kg/month Zison Pharmaceutical (Shandong) Co., Ltd.
4-Hydroxy-7-phenoxy-3-isoquinolinecarboxylic acid methyl ester pictures 2023-11-01 4-Hydroxy-7-phenoxy-3-isoquinolinecarboxylic acid methyl ester
1455091-10-7
 US $0.00 / kg 1kg 99% 200kg Hangzhou ICH Biofarm Co., Ltd
4-hydroxy-7-phenoxyisoquinoline-3-carboxylic acid methyl ester pictures 2023-11-01 4-hydroxy-7-phenoxyisoquinoline-3-carboxylic acid methyl ester
1455091-10-7
 US $0.00-0.00 / kg 1kg 99.0%min 100kg Hangzhou ICH Biofarm Co., Ltd

1455091-10-7(FG-4592 interMediate)Related Search:

4-Hydroxybenzyl alcohol 6-BROMO-3 H-ISOBENZOFURAN-1-ONE methyl 7-bromo-4-hydroxyisoquinoline-3-carboxylate methyl 4-hydroxy-6-phenoxyisoquinoline-3-carboxylate (R)-9-((triisopropylsilyl)oxy)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-5-onehydrochloride
7,8-dihydro-5H-cyclohepta[b]pyridine-5,9(6H)-dione 2-(2-Methyl-2H-tetrazol-5-yl)-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridine 1-(1-(1H-imidazole-1-carbonyl)piperidin-4-yl)-1H-imidazo[4,5-b]pyridin-2(3H)-one 4-Aminophthalimide 5-Aminophthalide
1(3H)-Isobenzofuranone, 5-phenoxy- INDEX NAME NOT YET ASSIGNED methyl 2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate methyl 1-chloro-4-hydroxy-7-phenoxyisoquinoline-3-carboxylate Roxadustat
4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinecarboxylic acid methyl ester

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FG-4592 interMediate FG4592 intermediates 4-Hydroxy-7-phenoxy-3-isoquinolinecarboxylic acid methyl ester Roxadustat Impurity 25 4-Hydroxy-7-phenoxy-3-isoquinolinecarboxylic acid methyl est... Roxadustat Impurities3 Roxadustat Impurity 4 FG-4592 INT 4-hydroxy-7-phenoxyisoquinoline-3-carboxylic acid methyl ester ROXA-030 4-Hydroxy-7-phenoxy-3-isoquinolinecarboxylic 3-Isoquinolinecarboxylic acid, 4-hydroxy-7-phenoxy-, methyl ester methyl 4-hydroxy-7-phenoxyisoquinoline-3-carboxylate Roxadustat Impurity 13 4-Hydroxy-7-phenoxy ascension quinoline-3-Methyl formate 4-Hydroxy-7-phenoxyisoquinoline-3-Methyl formate RSYY(Vorapaxar Sulfatet)-5 Rosalistat impurity 4 methyl 4-hydroxy-7-phenoxyisoquinoline-3-carboxylate（FG-4592 interMediate） 1455091-10-7 1055091-10-7 145509-10-7 Intermediate API