ChemicalBook >> CAS DataBase List >>(3R,5R)-5-[2-[2-[2-(3-METHOXYPHENYL)ETHYL]PHENOXY]ETHYL]-1-METHYL-3-PYRROLIDINOL HYDROCHLORIDE
(3R,5R)-5-[2-[2-[2-(3-METHOXYPHENYL)ETHYL]PHENOXY]ETHYL]-1-METHYL-3-PYRROLIDINOL HYDROCHLORIDE
- CAS No.
- 167144-79-8
- Chemical Name:
- (3R,5R)-5-[2-[2-[2-(3-METHOXYPHENYL)ETHYL]PHENOXY]ETHYL]-1-METHYL-3-PYRROLIDINOL HYDROCHLORIDE
- Synonyms
- R-96544HCl;R-96544 HYDROCHLORIDE;R96544 hydrochloride,R 96544 hydrochloride;(3R,5R)-5-(2-(2-(3-methoxyphenethyl)phenoxy)ethyl)-1-methylpyrrolidin-3-ol;3-Pyrrolidinol, 5-[2-[2-[2-(3-methoxyphenyl)ethyl]phenoxy]ethyl]-1-methyl-, (3R,5R)-;(2R,4R)-5-(2-(2-(2-(3-Methoxyphenyl)ethyl)phenoxy)ethyl)-1-methyl-3-pyrrolidinolhydrochloride;(3R,5R)-5-[2-[2-[2-(3-METHOXYPHENYL)ETHYL]PHENOXY]ETHYL]-1-METHYL-3-PYRROLIDINOL HYDROCHLORIDE
- CBNumber:
- CB1366589
- Molecular Formula:
- C22H29NO3
- Molecular Weight:
- 355.47
- MDL Number:
- MFCD06407939
- MOL File:
- 167144-79-8.mol
Last updated:2023-05-23 08:29:18
(3R,5R)-5-[2-[2-[2-(3-METHOXYPHENYL)ETHYL]PHENOXY]ETHYL]-1-METHYL-3-PYRROLIDINOL HYDROCHLORIDE price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Tocris | 1742 | R-96544hydrochloride ≥99%(HPLC) | 167144-79-8 | 10 | $193 | 2021-12-16 | Buy |
Tocris | 1742 | R-96544hydrochloride ≥99%(HPLC) | 167144-79-8 | 50 | $789 | 2021-12-16 | Buy |
Usbiological | 256398 | R-96544 hydrochloride | 167144-79-8 | 10mg | $446 | 2021-12-16 | Buy |
ApexBio Technology | B6842 | R-96544hydrochloride | 167144-79-8 | 50mg | $1189 | 2021-12-16 | Buy |
ApexBio Technology | B6842 | R-96544hydrochloride | 167144-79-8 | 10mg | $284 | 2021-12-16 | Buy |
(3R,5R)-5-[2-[2-[2-(3-METHOXYPHENYL)ETHYL]PHENOXY]ETHYL]-1-METHYL-3-PYRROLIDINOL HYDROCHLORIDE Chemical Properties,Uses,Production
Uses
R-96544 Hydrochloride is a the active form of a novel 5-HT2A receptor antagonist R-102444. It inhibits the platelet aggregation induced by serotonin (5-hydroxytryptamine, 5-HT).
Definition
ChEBI: (3R,5R)-5-[2-[2-[2-(3-methoxyphenyl)ethyl]phenoxy]ethyl]-1-methyl-3-pyrrolidinol is a stilbenoid.
Biological Activity
Potent, selective 5-HT 2 receptor antagonist; displays some selectivity for 5-HT 2A receptors (K i = 1.6 nM). IC 50 values are 2.2, 310, 2400, 3700, > 5000 and > 5000 nM for 5-HT 2 , a 1 -adrenergic, D 2 dopamine, 5-HT 1 , 5-HT 3 and b-adrenergic receptors respectively. Inhibits 5-HT-induced platelet aggregation and pressor responses in vivo .
Synthesis of (3R,5R)-5-[2-[2-[2-(3-METHOXYPHENYL)ETHYL]PHENOXY]ETHYL]-1-METHYL-3-PYRROLIDINOL HYDROCHLORIDE from (2R,4R)-ethyl 4-hydroxy-2-(2-(2-(3-methoxyphenethyl)phenoxy)ethyl)pyrrolidine-1-carboxylate
(3R,5R)-5-[2-[2-[2-(3-METHOXYPHENYL)ETHYL]PHENOXY]ETHYL]-1-METHYL-3-PYRROLIDINOL HYDROCHLORIDE Preparation Products And Raw materials
(3R,5R)-5-[2-[2-[2-(3-METHOXYPHENYL)ETHYL]PHENOXY]ETHYL]-1-METHYL-3-PYRROLIDINOL HYDROCHLORIDE Suppliers
Global( 13)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19994 | 58 |
3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44843 | 58 |
ApexBio Technology | -- | sales@apexbt.com | United States | 6254 | 58 |
Supplier | Advantage |
---|---|
TargetMol Chemicals Inc. | 58 |
Labnetwork lnc. | 58 |
3B Pharmachem (Wuhan) International Co.,Ltd. | 69 |
EMMX Biotechnology LLC | 60 |
Energy Chemical | 58 |
ApexBio Technology | 58 |
167144-79-8((3R,5R)-5-[2-[2-[2-(3-METHOXYPHENYL)ETHYL]PHENOXY]ETHYL]-1-METHYL-3-PYRROLIDINOL HYDROCHLORIDE)Related Search:
R-96544 HYDROCHLORIDE
(3R,5R)-5-[2-[2-[2-(3-METHOXYPHENYL)ETHYL]PHENOXY]ETHYL]-1-METHYL-3-PYRROLIDINOL HYDROCHLORIDE
(2R,4R)-5-(2-(2-(2-(3-Methoxyphenyl)ethyl)phenoxy)ethyl)-1-methyl-3-pyrrolidinolhydrochloride
R-96544HCl
(3R,5R)-5-(2-(2-(3-methoxyphenethyl)phenoxy)ethyl)-1-methylpyrrolidin-3-ol
3-Pyrrolidinol, 5-[2-[2-[2-(3-methoxyphenyl)ethyl]phenoxy]ethyl]-1-methyl-, (3R,5R)-
R96544 hydrochloride,R 96544 hydrochloride
167144-79-8
Serotonin receptor