1-METHOXY-1-TRIMETHYLSILYLOXYPROPENE
- CAS No.
- 34880-70-1
- Chemical Name:
- 1-METHOXY-1-TRIMETHYLSILYLOXYPROPENE
- Synonyms
- Methoxytrimethylsilyloxypropene;1-METHOXY-1-TRIMETHYLSILYLOXYPROPENE;1-methoxyprop-1-enoxy(trimethyl)silane;1-(Trimethylsiloxy)-1-methoxy-1-propene;1-Methoxy-1-trimethylsilyloxypropene>Trimethyl(1-methoxy-1-propenyloxy)silane;Methylketene methyl(trimethylsilyl)acetal;1-METHOXY-1-TRIMETHYLSILYLOXYPROPENE 95+%;[(1-METHOXY-1-PROPENYL)OXY]TRIMETHYLSILANE;Silane, [(1-methoxy-1-propenyl)oxy]trimethyl-
- CBNumber:
- CB1383968
- Molecular Formula:
- C7H16O2Si
- Molecular Weight:
- 160.29
- MDL Number:
- MFCD00671554
- MOL File:
- 34880-70-1.mol
| Boiling point | 52 °C / 27mmHg |
|---|---|
| Density | 0.87 |
| refractive index | 1.4130-1.4160 |
| storage temp. | 0-10°C |
| form | clear liquid |
| color | Colorless to Almost colorless |
| Specific Gravity | 0.87 |
| CAS DataBase Reference | 34880-70-1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H226-H315-H319 |
| Precautionary statements | P210-P233-P240-P241+P242+P243-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P370+P378-P403+P235-P501 |
| RIDADR | 1993 |
| HazardClass | 3 |
| PackingGroup | III |
| HS Code | 2931900090 |
1-METHOXY-1-TRIMETHYLSILYLOXYPROPENE price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | M1199 | 1-Methoxy-1-trimethylsilyloxypropene >95.0%(GC) | 34880-70-1 | 1g | $154 | 2025-07-31 | Buy |
| TCI Chemical | M1199 | 1-Methoxy-1-trimethylsilyloxypropene >95.0%(GC) | 34880-70-1 | 5g | $510 | 2025-07-31 | Buy |
| TRC | M337528 | 1-Methoxy-1-trimethylsilyloxypropene | 34880-70-1 | 500mg | $285 | 2021-12-16 | Buy |
| Usbiological | 284891 | 1-Methoxy-1-trimethylsilyloxypropene | 34880-70-1 | 250mg | $305 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | ING0001604 | 1-METHOXY-1-TRIMETHYLSILYLOXYPROPENE 95.00% | 34880-70-1 | 1G | $242.45 | 2021-12-16 | Buy |
1-METHOXY-1-TRIMETHYLSILYLOXYPROPENE Chemical Properties,Uses,Production
Uses
1-Methoxy-1-(trimethylsilyloxy)propene is used to reactive nucleophile in Mukaiyama-type aldol reactions with aldehydes, imines, acetals, dialkoxycarbenium ions, and orthoesters; Michael-type additions to α,β-unsaturated carbonyl compounds; substitution reactions with allylic alcohols and esters; acylations; aminations; hydroxylations; and pericyclic reactions; silylating agent.
Preparation
since the first preparation of a ketene trialkylsilyl acetal by Petrov in 1959 by the reaction
of triethylsilane and methyl acrylate, several alternative pathways have been explored. Ainsworth and coworkers prepared 1-methoxy-1-(trimethylsilyloxy)propene in 90% yield by deprotonation of methyl propionate
with Lithium Diisopropylamide at -78 °C followed by addition of Chlorotrimethylsilane. Reaction of the
lithium enolate of methyl acetate with TMS-Cl provides 65% O-silylated and 35% C-silylated products (eq 1).
Substitution on the alcohol portion of the ester favors C-silylation while substitution on the α-carbon favors O-silylation. An increase in the steric bulk of the silylating agent (e.g. use of t-Butyldimethylchlorosilane) results
in significantly more O-silylation.
storage
1-Methoxy-1-(trimethylsilyloxy)propene is easily hydrolyzed and oxidized by exposure to air. Storage is possible in sealed tubes at rt. Use in a fume hood.
1-METHOXY-1-TRIMETHYLSILYLOXYPROPENE Preparation Products And Raw materials
1-METHOXY-1-TRIMETHYLSILYLOXYPROPENE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-173 9270 1263 | 1057@dideu.com | China | 3944 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
| Alfa Chemistry | +1-5166625404; | Info@alfa-chemistry.com | United States | 20405 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; | peter68@ptchemgroup.com | China | 35425 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49983 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| Suzhou ARTK Medchem Co., Ltd. | +86-512-68323658 +86-18168183658 | sales1@artkmedchem.com | China | 39003 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532; 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 021-021-61259108 18621169085 | market03@meryer.com | China | 40228 | 62 |
View Lastest Price from 1-METHOXY-1-TRIMETHYLSILYLOXYPROPENE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-07-31 | 1-METHOXY-1-TRIMETHYLSILYLOXYPROPENE
34880-70-1
|
US $1.00 / KG | 1KG | 99% | 20T | Shaanxi Dideu Medichem Co. Ltd |
-
- 1-METHOXY-1-TRIMETHYLSILYLOXYPROPENE
34880-70-1
- US $1.00 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd
