4-(CYANOMETHYL)BENZOIC ACID
- CAS No.
- 50685-26-2
- Chemical Name:
- 4-(CYANOMETHYL)BENZOIC ACID
- Synonyms
- NSC 113990;Benzoic acid,4-(cyanomethyl)-;4-(CyanoMethyl)benzoic acid 98%;4-(Cyanomethyl)benzoic acid, 95%;4-(Cyanomethyl)benzoic acid - [C72726];4-Carboxyphenylacetonitrile, 4-Carboxybenzyl cyanide
- CBNumber:
- CB1511800
- Molecular Formula:
- C9H7NO2
- Molecular Weight:
- 161.16
- MDL Number:
- MFCD00020382
- MOL File:
- 50685-26-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 4-(Cyanomethyl)benzoicacid | C990118 | 50mg | $55 |
| 4-(Cyanomethyl)benzoic acid | 4637-1-P1 | 100mg | $55 |
| 4-(Cyanomethyl)benzoic acid | 4637-1-P1 | 1g | $280 |
| 4-(Cyanomethyl)benzoic acid 97% | 082058 | 1g | $405 |
| 4-(Cyanomethyl)benzoicacid | Y6260 | 5g | $519 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H312-H315-H319-H332-H335 |
| Precautionary statements | P261-P271-P280 |
| RIDADR | 2811 |
| HazardClass | 6.1 |
| PackingGroup | Ⅲ |
| HS Code | 2926907090 |
| Limited Quantities | 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid) |
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) |
4-(CYANOMETHYL)BENZOIC ACID price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | C990118 | 4-(Cyanomethyl)benzoicacid | 50685-26-2 | 50mg | $55 | 2021-12-16 | Buy |
| SynQuest Laboratories | 4637-1-P1 | 4-(Cyanomethyl)benzoic acid | 50685-26-2 | 100mg | $55 | 2021-12-16 | Buy |
| SynQuest Laboratories | 4637-1-P1 | 4-(Cyanomethyl)benzoic acid | 50685-26-2 | 1g | $280 | 2021-12-16 | Buy |
| Matrix Scientific | 082058 | 4-(Cyanomethyl)benzoic acid 97% | 50685-26-2 | 1g | $405 | 2021-12-16 | Buy |
| AK Scientific | Y6260 | 4-(Cyanomethyl)benzoicacid | 50685-26-2 | 5g | $519 | 2021-12-16 | Buy |
4-(CYANOMETHYL)BENZOIC ACID Chemical Properties,Uses,Production
Synthesis
76469-88-0
50685-26-2
General procedure for the synthesis of 4-(cyanomethyl)benzoic acid from methyl 4-(cyanomethyl)benzoate: Methyl 4-(cyanomethyl)benzoate (25 g, 0.14 mol) was dissolved in 300 mL of methanol, followed by the addition of 160 mL of a 1N NaOH solution, and the reaction was carried out at reflux for 3 hours. Upon completion of the reaction, most of the solvent was evaporated under reduced pressure. To the residue, 500 mL of water was added and the pH was adjusted to 2-3 with concentrated hydrochloric acid.The precipitated solid was filtered, washed with water and dried to give 4-(cyanomethyl)benzoic acid (21.2 g, 92.2% yield) as a white solid. The product was characterized by 1H NMR (400 MHz, DMSO-d6): δ 12.89 (brs, 1H), 7.87 (d, J=8.2 Hz, 2H), 7.37 (d, J=8.2 Hz, 2H), 3.45 (s, 2H); MS (EI): 161 [M]+.
References
[1] European Journal of Medicinal Chemistry, 2014, vol. 87, p. 765 - 781
[2] Patent: CN103724269, 2016, B. Location in patent: Paragraph 0610; 0611; 0626; 0627; 0628; 0629
[3] Patent: WO2011/69647, 2011, A1. Location in patent: Page/Page column 31
[4] Patent: EP2343287, 2011, A1. Location in patent: Page/Page column 21
4-(CYANOMETHYL)BENZOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14359 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
| Changzhou Anxuan Chemical Co., Ltd | +86-0519-89882563 +86-18961279162 | andy@anxuanchem.com | China | 4327 | 58 |
| Aromsyn Co., Ltd. | +86-0571-85585865 +8613336024896 | CB@aromsyn.com | China | 19183 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; | peter68@ptchemgroup.com | China | 35425 | 58 |
