ChemicalBook >> CAS DataBase List >>BAY 2666605
BAY 2666605
- CAS No.
- 2275774-60-0
- Chemical Name:
- BAY 2666605
- Synonyms
- BAY 266605;BAY 2666605;(S)-5-[4’-Fluoro-2-(trifluoromethyl)-4-biphenylyl]-6-methyl-3,6-dihydro-2H-1,3,4-oxadiazin-2-one;(S)-5-[4’-Fluoro-2-(trifluoromethyl)-4-biphenylyl]-6-methyl-3,6-dihydro-2H-1,3,4-oxadiazin-2-one;2H-1,3,4-Oxadiazin-2-one, 5-[4'-fluoro-2-(trifluoromethyl)[1,1'-biphenyl]-4-yl]-3,6-dihydro-6-methyl-, (6S)-;anticancer effect,inhibit,BAY 2666605,orally active,PDE3A-SLFN12 Complex,Phosphodiesterase (PDE),BAY2666605,BAY-2666605,Inhibitor
- CBNumber:
- CB210828953
- Molecular Formula:
- C17H12F4N2O2
- Molecular Weight:
- 352.28
- MDL Number:
- MOL File:
- 2275774-60-0.mol
Last updated:2024-06-07 15:13:09
| Density | 1.40±0.1 g/cm3(Predicted) |
|---|---|
| storage temp. | Store at -20°C |
| pka | 9.07±0.60(Predicted) |
| InChI | InChI=1S/C17H12F4N2O2/c1-9-15(22-23-16(24)25-9)11-4-7-13(14(8-11)17(19,20)21)10-2-5-12(18)6-3-10/h2-9H,1H3,(H,23,24)/t9-/m0/s1 |
| InChIKey | JNTJTCXFIXNXDV-VIFPVBQESA-N |
| SMILES | O1[C@@H](C)C(C2=CC=C(C3=CC=C(F)C=C3)C(C(F)(F)F)=C2)=NNC1=O |
| FDA UNII | XC4ZA6OSY6 |
BAY 2666605 Chemical Properties,Uses,Production
Uses
BAY 2666605 is an orally active PDE3A and PDE3B inhibitor with IC50s of 87 nM and 50 nM, respectively. BAY 2666605 is a PDE3A-SLFN12 complex inducer.
in vitro
BAY 2666605 has anticancer effects, potently inhibit brain cancer(especially glioma, more specifically glioblastoma, astrocytoma), breast cancer (especially ductal carcinoma and adenocarcinoma), cervical cancer, AML(especially erythroleucemia), lung cancer(especially NSCLC adenocarcinoma and SCLC), skin cancer(especially melanoma), oesophagus cancer (especially squamous cell carcinoma), ovarian cancer, (especially teratocarcinoma, adenocarcinoma), pancreas cancer and prostatic cancer.
BAY 2666605 Preparation Products And Raw materials
Raw materials
Preparation Products
BAY 2666605 Suppliers
Global( 17)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3136 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32715 | 60 |
| SUZHOU SENFEIDA CHEMICAL CO.,LTD | +86-0512-83500002 +8615195660023 | sales@senfeida.com | China | 10814 | 58 |
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 | sales-cpd@caerulumpharma.com | China | 3427 | 58 |
| Shanghai XingMo Biotechnology Co., Ltd. | 13524779951 | 2075692521@qq.com | China | 310 | 55 |
| Chengdu DingDang Pharmaceutical Co., Ltd. | 028-86040038 13980902949; | market@dingdangchem.com | China | 1758 | 55 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 010-50973130 4009686088 | 3193328036@qq.com | China | 29796 | 68 |
| Nantong Hi-Future Biotechnology Co., Ltd | 18051384581 | sales@chemhifuture.com | China | 3061 | 58 |
| Changzhou Borl Biotechnology Co.,LTD | 13606124132;13656121842 | luyan0021@163.com | China | 217 | 58 |
2275774-60-0(BAY 2666605)Related Search:
BAY 2666605
anticancer effect,inhibit,BAY 2666605,orally active,PDE3A-SLFN12 Complex,Phosphodiesterase (PDE),BAY2666605,BAY-2666605,Inhibitor
2H-1,3,4-Oxadiazin-2-one, 5-[4'-fluoro-2-(trifluoromethyl)[1,1'-biphenyl]-4-yl]-3,6-dihydro-6-methyl-, (6S)-
BAY 266605
(S)-5-[4’-Fluoro-2-(trifluoromethyl)-4-biphenylyl]-6-methyl-3,6-dihydro-2H-1,3,4-oxadiazin-2-one
(S)-5-[4’-Fluoro-2-(trifluoromethyl)-4-biphenylyl]-6-methyl-3,6-dihydro-2H-1,3,4-oxadiazin-2-one
2275774-60-0