Zilantel
- CAS No.
- 22012-72-2
- Chemical Name:
- Zilantel
- Synonyms
- Zilantel;Cl-64976;(Ethylenebisthio)bis[N-(diethoxyphosphinyl)formimidothioic acid benzyl] ester;9-Oxa-2,5-dithia-7-aza-8-phosphaundec-6-enimidothioic acid, N-(diethoxyphosphinyl)-8-ethoxy-6-[(phenylmethyl)thio]-, 1-(phenylmethyl) ester, 8-oxide
- CBNumber:
- CB21180097
- Molecular Formula:
- C26H38N2O6P2S4
- Molecular Weight:
- 664.8
- MDL Number:
- MFCD00864545
- MOL File:
- 22012-72-2.mol
| Boiling point | 706.6±70.0 °C(Predicted) |
|---|---|
| Density | 1.28±0.1 g/cm3(Predicted) |
| pka | -5.97±0.50(Predicted) |
| FDA UNII | I50276Z58E |
Zilantel Chemical Properties,Uses,Production
Originator
Zilantel,ZYF Pharm Chemical
Uses
Anthelmintic.
Manufacturing Process
To a mixture of 1.48 parts of ethanedithiol and 3.4 parts of triethylamine in 30 ml of benzene is added, with cooling, 5.7 parts of diethoxyphosphinyl isothiocyanate. After an hour, this mixture is added to 5.7 parts of benzyl bromide in 25 parts by volume of toluene in several portions over a 10 min period (mild temperature rise to 29°C). After stirring over night, the mixture is diluted with more benzene, washed (including dilute sodium hydroxide), and concentrated to give 10.7 parts of oil. Column chromatography on a total of 150 parts of silica gel yields, on sequential elution with 1:1 carbon tetrachloride:chloroform, chloroform and 2-10% methanol in chloroform, 4.5 parts (42%) crude product. The 2.0 parts of colorless crystalline of S,S'- ethylene-S,S'-dibenzyl-diethoxyphosphinylimidodithiocarbonate, melting point 67.5-68.5°C (recrystallization from ether) are obtained.
Therapeutic Function
Anthelmintic, Pesticide
Zilantel Preparation Products And Raw materials
Zilantel Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Lanospharma Laboratories Co.,Ltd | -- | sales@lanospharma.com | China | 6343 | 56 |
| Shanghai New Union Textra Import & Export Co., Ltd | -- | zhou@pharmchemical.com | China | 2752 | 60 |
| Supplier | Advantage |
|---|---|
| Lanospharma Laboratories Co.,Ltd | 56 |
| Shanghai New Union Textra Import & Export Co., Ltd | 60 |