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GUVACINE HYDROCHLORIDE

CAS No.
498-96-4
Chemical Name:
GUVACINE HYDROCHLORIDE
Synonyms
GUVACINE;GUVACINE-HCL;1,2,5,6-tetrahydronicotinic acid;1,2,5,6-tetrahydro-3-pyridinecarboxylic acid;1,2,5,6-Tetrahydropyridine-3-carboxylic acid;1,2,3,6-tetrahydropyridine-5-carboxylic acid;3-Pyridinecarboxylic acid, 1,2,5,6-tetrahydro-;1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE;1,2,5,6-tetrahydropyridine-3-carboxylic acid(SALTDATA: HCl)
CBNumber:
CB2165839
Molecular Formula:
C6H9NO2
Molecular Weight:
127.14
MDL Number:
MFCD01365700
MOL File:
498-96-4.mol
MSDS File:
SDS
Last updated:2023-08-23 18:01:39

GUVACINE HYDROCHLORIDE Properties

Melting point 295°C (rough estimate)
Boiling point 235.91°C (rough estimate)
Density 1.1931 (rough estimate)
refractive index 1.4645 (estimate)
storage temp. Store at RT
solubility H2O: soluble
pka 3.61±0.20(Predicted)
form solid
color white
CAS DataBase Reference 498-96-4
FDA UNII 41538P325K

SAFETY

Risk and Safety Statements

Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
HazardClass  IRRITANT

GUVACINE HYDROCHLORIDE price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 255418 Guvacine hydrochloride 498-96-4 100mg $446 2021-12-16 Buy
American Custom Chemicals Corporation PXT0004202 GUVACINE 95.00% 498-96-4 50MG $258.3 2021-12-16 Buy
ChemScene CS-0022753 Guvacine 498-96-4 1mg $150 2021-12-16 Buy
Biorbyt Ltd orb105361 Guvacine hydrochloride >98%,Standard References Grade 498-96-4 20mg $569.5 2021-12-16 Buy
American Custom Chemicals Corporation PXT0004202 GUVACINE 95.00% 498-96-4 100MG $702.19 2021-12-16 Buy
Product number Packaging Price Buy
255418 100mg $446 Buy
PXT0004202 50MG $258.3 Buy
CS-0022753 1mg $150 Buy
orb105361 20mg $569.5 Buy
PXT0004202 100MG $702.19 Buy

GUVACINE HYDROCHLORIDE Chemical Properties,Uses,Production

Uses

Guvacine Hydrochloride is a GABA uptake inhibitor (hGABA T-1, rGABA T-2, hGABA T-3 and hBGT-1) (1,2,3). Gamma-Aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain (4). Guvacine Hydrochloride may be useful for treating neuropsychiatric disorders.

Definition

ChEBI: A alpha,beta-unsaturated monocarboxylic acid that is nicotinic acid which has been hydrogenated at the 1-2 and 5-6 positions of the pyridine ring.

Biological Activity

Specific GABA uptake inhibitor. IC 50 values are 14, 58, 119 and 1870 mM for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively.

GUVACINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 104)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Haibo Biotechnology Co., Ltd
+undefined18602966907 qinhe02@xaltbio.com China 1000 58
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3620 58
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Chengdu Biopurify Phytochemicals Ltd.
+8618080483897 sales@biopurify.com China 3424 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49390 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671 sales@tnjchem.com China 34572 58
changzhou huayang technology co., ltd
+8615250961469 2571773637@qq.com China 9821 58
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd
+8618829768577 gao490372054@gamil.com China 1250 58

View Lastest Price from GUVACINE HYDROCHLORIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Guvacine pictures 2024-04-12 Guvacine
498-96-4
US $0.00 / kg 1kg 99% 2000ton Shaanxi Haibo Biotechnology Co., Ltd
GUVACINE HYDROCHLORIDE pictures 2019-07-14 GUVACINE HYDROCHLORIDE
498-96-4
US $1.00 / KG 1KG 99% 25kg Career Henan Chemical Co
  • Guvacine pictures
  • Guvacine
    498-96-4
  • US $0.00 / kg
  • 99%
  • Shaanxi Haibo Biotechnology Co., Ltd
GUVACINE 1,2,5,6-tetrahydro-3-pyridinecarboxylic acid 1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE GUVACINE-HCL 1,2,5,6-tetrahydronicotinic acid 1,2,5,6-tetrahydropyridine-3-carboxylic acid(SALTDATA: HCl) 1,2,5,6-Tetrahydropyridine-3-carboxylic acid 3-Pyridinecarboxylic acid, 1,2,5,6-tetrahydro- 1,2,3,6-tetrahydropyridine-5-carboxylic acid 498-96-4 C5H8NCOOH GABA uptake inhibitor. BioChemical Cell Signaling and Neuroscience Cell Biology GABA and Glycine Receptor Modulators Ligand-Gated Ion Channels Ion Channels GABA/Glycine receptor