Ethyl 2-(2,4-dichlorophenyl)thiazole-4-carboxylate
- CAS No.
- 1185155-89-8
- Chemical Name:
- Ethyl 2-(2,4-dichlorophenyl)thiazole-4-carboxylate
- Synonyms
- thiazole-4-carboxylate;Ethyl 2-(2,4-dichlorophenyl);Ethyl 2-(2,4-dichlorophenyl)thiazole-4-carboxylate;2-(2,4-Dichlorophenyl)-4-thiazolecarboxylic acid ethyl ester;4-Thiazolecarboxylic acid, 2-(2,4-dichlorophenyl)-, ethyl ester
- CBNumber:
- CB22471134
- Molecular Formula:
- C12H9Cl2NO2S
- Molecular Weight:
- 302.18
- MDL Number:
- MFCD09743715
- MOL File:
- 1185155-89-8.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
Ethyl 2-(2,4-dichlorophenyl)thiazole-4-carboxylate price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | E915923 | Ethyl2-(2,4-dichlorophenyl)thiazole-4-carboxylate | 1185155-89-8 | 50mg | $85 | 2021-12-16 | Buy |
| Matrix Scientific | 072060 | Ethyl 2-(2,4-dichlorophenyl)thiazole-4-carboxylate 95+% | 1185155-89-8 | 5g | $685 | 2021-12-16 | Buy |
| Matrix Scientific | 072060 | Ethyl 2-(2,4-dichlorophenyl)thiazole-4-carboxylate 95+% | 1185155-89-8 | 1g | $342 | 2021-12-16 | Buy |
| AK Scientific | X9259 | Ethyl2-(2,4-dichlorophenyl)thiazole-4-carboxylate | 1185155-89-8 | 5g | $974 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0050352 | 2-(2,4-DICHLOROPHENYL)THIAZOLE-4-CARBOXYLIC ACID ETHYL ESTER 95.00% | 1185155-89-8 | 1G | $1085.7 | 2021-12-16 | Buy |
Ethyl 2-(2,4-dichlorophenyl)thiazole-4-carboxylate Chemical Properties,Uses,Production
Synthesis
70-23-5
2775-38-4
1185155-89-8
To a 250 mL round bottom flask was added 2,4-dichlorobenzene-1-carbothioamide (4.0 g, 19 mmol, CAS 2775-38-4), ethyl 3-bromo-2-oxopropionate (10.0 g, 51 mmol), ethanol (20 mL) and pyridine (4.8 g, 61 mmol). The reaction mixture was stirred at 80 °C overnight. After completion of the reaction, the mixture was cooled to room temperature and concentrated under reduced pressure. The residue was purified by silica gel column chromatography with ethyl acetate/petroleum ether (1:5) as eluent to afford ethyl 2-(2,4-dichlorophenyl)-1,3-thiazole-4-carboxylate (2.0 g, 31% yield) as a yellow solid.LC-MS: m/z = 302.0 [M + H]+, tR = 1.3 min. 1H NMR (300 MHz, CDCl3) δ 8.32 (s, 1H), 7.54 (d, J = 2.1 Hz, 1H), 7.39 (dd, J = 8.6, 2.1 Hz, 1H), 4.48 (q, J = 7.1 Hz, 2H), 1.45 (t, J = 7.1 Hz, 3H).
References
[1] Patent: WO2018/106636, 2018, A1. Location in patent: Paragraph 00288
[2] Chemical Biology and Drug Design, 2016, p. 26 - 37
Ethyl 2-(2,4-dichlorophenyl)thiazole-4-carboxylate Preparation Products And Raw materials
Ethyl 2-(2,4-dichlorophenyl)thiazole-4-carboxylate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30229 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10186 | 62 |
| SynAsst Chemical. | 021-60343070 | China | 12740 | 55 | |
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| Aikon International Limited | 025-58859352 18068836627 | sales01@aikonchem.com | China | 16027 | 58 |
| Shanghai Jizhi Biochemical Technology Co. Ltd. | 4009004166/18616739031 18616739031 | 3007523370@qq.com | China | 52693 | 58 |
