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CZC-54252

CZC-54252 Structure
CZC-54252 structure
CAS No.
1191911-27-9
Chemical Name:
CZC-54252
Synonyms
CS-1730;CZC-54252;CZC-54252, >98%;CZC 54252;CZC54252;CZC 54252 hydrochloride;N-(2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)pyrimidin-4-ylamino)phenyl)methanesulfonamide;LRRK2,LRRK2-G2019S,inhibit,neuronal,CZC-54252,injury,neuroprotective,Leucine-rich repeat kinase 2,Inhibitor;N-{2-[(5-chloro-2-{[2-methoxy-4-(morpholin-4-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}methanesulfonamide;Methanesulfonamide, N-[2-[[5-chloro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]phenyl]-;N-[2-[[5-Chloro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]phenyl]methanesulfonamide hydrochloride
CBNumber:
CB22738769
Molecular Formula:
C22H25ClN6O4S
Molecular Weight:
504.99
MDL Number:
MFCD26401527
MOL File:
1191911-27-9.mol
MSDS File:
SDS
Last updated:2023-09-20 16:43:00
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CZC-54252 Properties

Boiling point 718.1±70.0 °C(Predicted)
Density 1.452±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility DMF: 20 mg/mL; DMF:PBS(pH 7.2)(1:1): 0.5 mg/mL; DMSO: 10 mg/mL
form Powder
pka 8.50±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
NFPA 704
0
2 0

CZC-54252 price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 17998 CZC 54252 ≥98% 1191911-27-9 1mg $44 2024-03-01 Buy
Cayman Chemical 17998 CZC 54252 ≥98% 1191911-27-9 5mg $130 2024-03-01 Buy
Cayman Chemical 17998 CZC 54252 ≥98% 1191911-27-9 10mg $235 2024-03-01 Buy
Cayman Chemical 17998 CZC 54252 ≥98% 1191911-27-9 25mg $533 2024-03-01 Buy
Tocris 4534 CZC54252hydrochloride ≥98%(HPLC) 1191911-27-9 50 $906 2021-12-16 Buy
Product number Packaging Price Buy
17998 1mg $44 Buy
17998 5mg $130 Buy
17998 10mg $235 Buy
17998 25mg $533 Buy
4534 50 $906 Buy

CZC-54252 Chemical Properties,Uses,Production

Uses

CZC 54252 is an inhibitor of leucine-rich repeat kinase 2 (LRRK2). LRRK2 mutations are associated with familial Parkinson''s disease and a potential therapeutic target.

Definition

ChEBI: CZC-25146 is a member of the class of aminopyrimidines that is 2,6-diamino-5-chloropyrimidine in which the amino groups at positions 2 and 6 are respectively carrying 2-methoxy-4-(morpholin-4-yl)phenyl and 2-(methanesulfonylamino)phenyl substituents. It is an inhibitor of the Parkinson's disease kinase LRRK2. It has a role as an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor. It is an aminopyrimidine, a member of morpholines, an aromatic ether, an organochlorine compound, a sulfonamide and a secondary amino compound.

CZC-54252 Preparation Products And Raw materials

Raw materials

Methanesulfonyl chloride

Preparation Products

CZC-54252 Suppliers

Global( 62)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32715 60
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Career Henan Chemica Co 		+86-0371-86658258 15093356674; laboratory@coreychem.com China 30255 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		13417589054 trendseenbio@gmail.com China 11681 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 57511 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131980 58
Haoyuan Chemexpress Co., Ltd. 021-58950125 info@chemexpress.com China 7553 61
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4863 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
TargetMol Chemicals Inc. 		58
Career Henan Chemica Co 		58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		58
InvivoChem 		58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		58
Aladdin Scientific 		58
Amadis Chemical Company Limited 		58
Haoyuan Chemexpress Co., Ltd. 61
MedChemexpress LLC 58

View Lastest Price from CZC-54252 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
CZC-54252 pictures 2021-01-06 CZC-54252
1191911-27-9
 US $1.00 / KG 1KG MIn98%HPLC/LC 100KGS Career Henan Chemica Co
  • CZC-54252 pictures
  • CZC-54252
    1191911-27-9
  • US $1.00 / KG
  • MIn98%HPLC/LC
  • Career Henan Chemica Co

CZC-54252 Spectrum

CZC-54252(1191911-27-9)1HNMR
N-(2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)pyrimidin-4-ylamino)phenyl)methanesulfonamide CZC 54252 hydrochloride CZC-54252 CS-1730 N-[2-[[5-Chloro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]phenyl]methanesulfonamide hydrochloride CZC 54252;CZC54252 CZC-54252, >98% Methanesulfonamide, N-[2-[[5-chloro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]phenyl]- N-{2-[(5-chloro-2-{[2-methoxy-4-(morpholin-4-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}methanesulfonamide LRRK2,LRRK2-G2019S,inhibit,neuronal,CZC-54252,injury,neuroprotective,Leucine-rich repeat kinase 2,Inhibitor 1191911-27-9 C22H25ClN6O4S C22H25ClN6O4SHCl Inhibitors