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2-Propenoic acid, 3,3'-(1,3-phenylene)bis-

CAS No.
37710-81-9
Chemical Name:
2-Propenoic acid, 3,3'-(1,3-phenylene)bis-
Synonyms
TC AQP1 1;m-Benzenediacrylic acid;m-Phenylenediacrylic acid;TC-AQP-1-1,TCAQP11,TC AQP1 1;2-Propenoic acid, 3,3'-(1,3-phenylene)bis-;2-Propenoic acid, 3,3'-(1,3-phenylene)bis-
CBNumber:
CB23207516
Molecular Formula:
C12H10O4
Molecular Weight:
218.21
MDL Number:
MFCD00021776
MOL File:
37710-81-9.mol
Last updated:2023-09-04 15:51:00

2-Propenoic acid, 3,3'-(1,3-phenylene)bis- Properties

Boiling point 458.7±33.0 °C(Predicted)
Density 1.358±0.06 g/cm3(Predicted)
storage temp. RT
solubility Soluble in DMSO (up to 25 mg/ml).
pka 4.07±0.10(Predicted)
form solid
color White
Stability Stable for 1 year from date of pruchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.

2-Propenoic acid, 3,3'-(1,3-phenylene)bis- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Tocris 5412 TCAQP11 ≥98%(HPLC) 37710-81-9 10 $106 2021-12-16 Buy
Tocris 5412 TCAQP11 ≥98%(HPLC) 37710-81-9 50 $445 2021-12-16 Buy
TRC T120105 TCAQP11 37710-81-9 10mg $100 2021-12-16 Buy
Usbiological 256822 TC AQP1 1 37710-81-9 10mg $339 2021-12-16 Buy
Atlantic Research Chemicals CA001841 3-[3-(2-Carboxyeth-1-en-1-yl)phenyl]prop-2-enoicacid 95% 37710-81-9 1gm: $420.61 2021-12-16 Buy
Product number Packaging Price Buy
5412 10 $106 Buy
5412 50 $445 Buy
T120105 10mg $100 Buy
256822 10mg $339 Buy
CA001841 1gm: $420.61 Buy

2-Propenoic acid, 3,3'-(1,3-phenylene)bis- Chemical Properties,Uses,Production

Description

CVPA (37710-81-9) is an aquaporin-1 inhibitor (IC50 = 8.1 μM) discovered by molecular docking against the extracellular domain of human aquaporin-1 followed by experimental testing in a Xenopus oocyte swelling assay.1

Uses

TC AQP1 1 is a human aquaoporin-1 (hAQP1) selective inhibitor and is considered to have therapeutic potential towards the potential treatment of glaucoma, brain edema, inflammatory pain and certain types of cancer.

storage

Store at +4°C

References

1) Seeliger et al. (2012), Discovery of novel human aquaporin-1 blockers; ACS Chem. Biol., 8 249

626-19-7
141-82-2
37710-81-9
Synthesis of 2-Propenoic acid, 3,3'-(1,3-phenylene)bis- from m-Phthalaldehyde and Malonic acid

2-Propenoic acid, 3,3'-(1,3-phenylene)bis- Preparation Products And Raw materials

Raw materials

Preparation Products

2-Propenoic acid, 3,3'-(1,3-phenylene)bis- Suppliers

Global( 23)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Nantong HI-FUTURE Biology Co., Ltd.
+undefined18051384581 sales@chemhifuture.com China 3136 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 57511 58
Shanghai ChuangYan Chemical Technology Co., Ltd. 021-11111111 11111111111 546919421@qq.com China 3014 55
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
BOC Sciences -- info@bocsci.com USA 0 65
Changzhou Chenhong Biotechnology Co., Ltd. 0519-85788828 13775037613 sales@chemrenpharm.com China 3574 58
Nantong Hi-Future Biotechnology Co., Ltd 18051384581 sales@chemhifuture.com China 3061 58
Hefei Mokai Pharmaceutical Technology Co., Ltd 18130062233 3362556465@qq.com China 8000 58
InvivoChem 13549236410 sales@invivochem.cn China 6749 58

2-Propenoic acid, 3,3'-(1,3-phenylene)bis- Spectrum

2-Propenoic acid, 3,3'-(1,3-phenylene)bis- TC AQP1 1 TC-AQP-1-1,TCAQP11,TC AQP1 1 2-Propenoic acid, 3,3'-(1,3-phenylene)bis- m-Benzenediacrylic acid m-Phenylenediacrylic acid 37710-81-9