Sulfamide
- CAS No.
- 7803-58-9
- Chemical Name:
- Sulfamide
- Synonyms
- SULFURIC DIAMIDE;SULPHAMIDE;SulfaMid;famide;NSC 252;SULFAMIDE;Suleamide;Sulfamamide;[S(NH2)2O2];Sulfamide >
- CBNumber:
- CB2488651
- Molecular Formula:
- H4N2O2S
- Molecular Weight:
- 96.11
- MDL Number:
- MFCD00011606
- MOL File:
- 7803-58-9.mol
- MSDS File:
- SDS
Melting point | 90-92 °C(lit.) |
---|---|
Density | 1.611 g/mL at 25 °C(lit.) |
storage temp. | Inert atmosphere,Room Temperature |
solubility | water: soluble50mg/mL, clear, colorless to faintly yellow |
form | Crystalline Powder, Free From Visible Impurities |
pka | 10.87±0.60(Predicted) |
color | White to practically white , free from visible impurities |
PH | 5.67 at 21.7℃ and 10g/L |
Water Solubility | soluble |
Sensitive | Moisture Sensitive |
Merck | 14,8922 |
InChIKey | NVBFHJWHLNUMCV-UHFFFAOYSA-N |
CAS DataBase Reference | 7803-58-9(CAS DataBase Reference) |
FDA UNII | VS7TZW634V |
NIST Chemistry Reference | Sulfamide(7803-58-9) |
EPA Substance Registry System | Sulfamide (7803-58-9) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 26-36-37/39 | |||||||||
WGK Germany | 3 | |||||||||
F | 9 | |||||||||
TSCA | Yes | |||||||||
HazardClass | IRRITANT | |||||||||
HS Code | 28530090 | |||||||||
NFPA 704 |
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Sulfamide price More Price(42)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 211370 | Sulfamide 99% | 7803-58-9 | 5g | $36.1 | 2024-03-01 | Buy |
Sigma-Aldrich | 211370 | Sulfamide 99% | 7803-58-9 | 25g | $85.8 | 2024-03-01 | Buy |
TCI Chemical | S0890 | Sulfamide >96.0%(N) | 7803-58-9 | 25g | $30 | 2024-03-01 | Buy |
TCI Chemical | S0890 | Sulfamide >96.0%(N) | 7803-58-9 | 250g | $141 | 2024-03-01 | Buy |
Alfa Aesar | A18680 | Sulfamide 99% | 7803-58-9 | 2.5g | $45.65 | 2024-03-01 | Buy |
Sulfamide Chemical Properties,Uses,Production
Description
Sulfamide is a white solid substance that is normally produced by reacting sulfuryl chloride with ammonia. Sulfamide is stable under normal conditions and soluble in acetone and DMSO. Sulfamide may also refer to the functional group in organic chemistry, and it consists of at least one group attached to a nitrogen atom of sulfamide.
It is a carbonic anhydrase inhibitor and is widely used as a pharmaceutical intermediate.
Sulfamide is sensitive to moisture, thus should be kept away from water and humidity. It should also be stored away from oxidizing agents. Sulfamide should be kept in a tightly closed container and placed in a cool, dry, and well-ventilated condition.
Chemical Properties
White Solid
Uses
Similar to urea in many of its reactions, but is more acidic, and can act as a dibasic acid.
Uses
A carbonic anhydrase inhibitor; used for treatment of cancer.
Uses
Sulfamide and its derivatives can also be used to prepare fused thiadiazine systems, Reaction with 2-aminoacetophenones affords IH-2,1,3-benzothia- diazine 2,2-dioxides 77 (65JOC3960). The corresponding 3,4-dihydro deriv- atives are readily available from 2-aminobenzylamines with either sulfuryl chloride (70M1443) or sulfamide (66USP3278532; 71MI055). These kinds of compounds can also be obtained from N-aryl-N'-alkylsulfamides and s-trioxane in a reaction involving cyclization by intramolecular sulfamido- methylation (79JOC2032) (Scheme 30).
Definition
ChEBI: The simplest of the sulfamic acids consisting of a single sulfur atom covalently bound by single bonds to two amino groups and by double bonds to two oxygen atoms.
Purification Methods
Crystallise sulfamide from absolute EtOH. It decomposes at 250o. [Schenk in Handbook of Preparative Inorganic Chemistry (Ed. Brauer) Academic Press Vol I pp 482-483 1963.]
Sulfamide Preparation Products And Raw materials
Raw materials
Preparation Products
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Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12446 | 58 |
Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5873 | 58 |
airuikechemical co., ltd. | +undefined86-15315557071 | sales02@sdzhonghuimaterial.com | China | 983 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21667 | 55 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9355 | 55 |
Hubei XinRunde Chemical Co., Ltd. | +8615102730682 | bruce@xrdchem.cn | CHINA | 566 | 55 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +8618949832763 | info@tnjchem.com | China | 2989 | 55 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29888 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
View Lastest Price from Sulfamide manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-08-30 | Sulfamide
7803-58-9
|
US $825.00 / KG | 25KG | 99% | 2000T | Baoji Guokang Bio-Technology Co., Ltd. | ||
2024-08-15 | Sulfamide
7803-58-9
|
US $50.00 / kg | 1kg | 0.99 | 10000 | Hebei Yanxi Chemical Co., Ltd. | ||
2024-04-28 | Sulfamide
7803-58-9
|
US $15.00 / kg | 1kg | 99.912% | 10ton | Ouhuang Engineering Materials (Hubei) Co., Ltd |
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