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Yangambin

CAS No.
13060-14-5
Chemical Name:
Yangambin
Synonyms
C10894;YANGAMBIN;(+)-Yangabin;Lrioresinol B dimethyl ether;Lirioresinol B dimethyl ether;(+)-O,O-Dimethyl lirioresinol B;yangambin/Lrioresinol B dimethyl ether;inhibit,Calcium Channel,Yangambin,Ca channels,Ca2+ channels,Inhibitor;(1β,5β)-2β,6β-Bis(3,4,5-trimethoxyphenyl)-3,7-dioxabicyclo[3.3.0]octane;(1S,3aR,4S,6aR)-Tetrahydro-1,4-bis(3,4,5-trimethoxyphenyl)-1H,3H-furo[3,4-c]furan
CBNumber:
CB31246402
Molecular Formula:
C24H30O8
Molecular Weight:
446.49
MDL Number:
MFCD04307767
MOL File:
13060-14-5.mol
MSDS File:
SDS
Last updated:2023-09-20 16:43:00

Yangambin Properties

Melting point 105-106 °C
Boiling point 556.1±50.0 °C(Predicted)
Density 1.183±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO

Yangambin price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0032586 Yangambin 13060-14-5 5mg $880 2021-12-16 Buy
ChemScene CS-0032586 Yangambin 13060-14-5 10mg $1500 2021-12-16 Buy
Arctom CFN96416 Yangambin ≥98% 13060-14-5 5mg $398 2021-12-16 Buy
Crysdot CD32002589 Yangambin 95+% 13060-14-5 5mg $723 2021-12-16 Buy
Product number Packaging Price Buy
CS-0032586 5mg $880 Buy
CS-0032586 10mg $1500 Buy
CFN96416 5mg $398 Buy
CD32002589 5mg $723 Buy

Yangambin Chemical Properties,Uses,Production

Uses

Yangambin is one of the active ingredients of Radix Stellerae Chamaejasmes, which is bitter in nature and taste, and is highly toxic. It has the effects of severe diarrhea, prevent decay, and swelling. It is clinically used for erysipelas, mammary carbuncle, swollen mumps (mumps), yellow water sores, and acne.

Definition

ChEBI: Yangambin is a lignan.

Biological Activity

Yangambin is a furofuran lignan that has been isolated from plants such as the Annonaceae family, including: R. pickeli, R. exalbida and R. mucosa and Magnolia biondii. Yangambin is a selective PAF receptor antagonist that inhibits Ca2+ influx by modulating Ca2+ channels, resulting in a decrease in [Ca2+] in vascular smooth muscle cells and subsequent peripheral vasodilation. Yangambin exhibits anti-allergic activity against β-hexosaminidase with IC50 of 33.8 μM and anti-inflammatory activity with IC50 of 37.4 μM.

Yangambin Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 50)Suppliers
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Yangambin Spectrum

Lrioresinol B dimethyl ether (1S,3aR,4S,6aR)-Tetrahydro-1,4-bis(3,4,5-trimethoxyphenyl)-1H,3H-furo[3,4-c]furan (+)-Yangabin C10894 YANGAMBIN (+)-O,O-Dimethyl lirioresinol B (1S)-1β,4β-Bis(3,4,5-trimethoxyphenyl)-3aβ,4,6,6aβ-tetrahydro-1H,3H-furo[3,4-c]furan (1β,5β)-2β,6β-Bis(3,4,5-trimethoxyphenyl)-3,7-dioxabicyclo[3.3.0]octane [1S,(+)]-3aβ,4,6,6aβ-Tetrahydro-1β,4β-bis(3,4,5-trimethoxyphenyl)-1H,3H-furo[3,4-c]furan Lirioresinol B dimethyl ether 1H,3H-Furo[3,4-c]furan, tetrahydro-1,4-bis(3,4,5-trimethoxyphenyl)-, (1S,3aR,4S,6aR)- yangambin/Lrioresinol B dimethyl ether (3S,3aR,6S,6aR)-3,6-bis(3,4,5-trimethoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan inhibit,Calcium Channel,Yangambin,Ca channels,Ca2+ channels,Inhibitor 13060-14-5 13060-54-5