Mosapride
- CAS No.
- 112885-41-3
- Chemical Name:
- Mosapride
- Synonyms
- Moza;Mosapid;TAK-370;Mosid-MT;MOSAPRIDE;Mosapride reference;Mosapride USP/EP/BP;((4-(4-fluorobenzyl)-2-morpholinyl)methyl)benzamide/mosapride;4-AMINO-5-CHLORO-2-ETHOXY-N-((4-(4-FLUOROBENZYL)-2-MORPHOLINYL)METHYL)BENZAMIDE;4-AMINO-5-CHLORO-2-ETHOXY-N-[4-(4-FLUORO-BENZYL)-MORPHOLIN-2-YLMETHYL]-BENZAMIDE
- CBNumber:
- CB3273304
- Molecular Formula:
- C21H25ClFN3O3
- Molecular Weight:
- 421.89
- MDL Number:
- MFCD00867430
- MOL File:
- 112885-41-3.mol
- MSDS File:
- SDS
Melting point | 151-153°C |
---|---|
Boiling point | 549.2±50.0 °C(Predicted) |
Density | 1.272±0.06 g/cm3(Predicted) |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | DMSO (Slightly), Methanol (Slightly) |
form | Solid |
pka | 13.52±0.46(Predicted) |
color | White to Off-White |
CAS DataBase Reference | 112885-41-3(CAS DataBase Reference) |
FDA UNII | I8MFJ1C0BY |
ATC code | A03FA09 |
Mosapride price More Price(24)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | M731000 | Mosapride | 112885-41-3 | 100mg | $215 | 2021-12-16 | Buy |
Usbiological | M4676-20 | Mosapride | 112885-41-3 | 10mg | $382 | 2021-12-16 | Buy |
Usbiological | 282965 | Mosapride | 112885-41-3 | 50g | $921 | 2021-12-16 | Buy |
Matrix Scientific | 074845 | 4-Amino-5-chloro-2-ethoxy-N-((4-(4-fluorobenzyl)-2-morpholinyl)methyl)benzamide 95+% | 112885-41-3 | 5g | $998 | 2021-12-16 | Buy |
Matrix Scientific | 074845 | 4-Amino-5-chloro-2-ethoxy-N-((4-(4-fluorobenzyl)-2-morpholinyl)methyl)benzamide 95+% | 112885-41-3 | 1g | $370 | 2021-12-16 | Buy |
Mosapride Chemical Properties,Uses,Production
Description
Mosapride citrate, a new gastroprokinetic benzamide was introduced in Japan as Gasmotin for the relief of gastrointestinal symptoms in patients with chronic gastritis, gastro-oesophageal reflux, dyspepsia and post-surgery use. Mosapride is synthesized by final amidation between the corresponding benzoic acid, itself obtained in 3 steps from methyl 4-acetamido salicylate, and the appropriate 2-aminomethyl-morpholine. Mosapride is a 5-HT4 partial agonist without notable activity for D2, 5-HT1 , 5-HT2, alpha-1 and alpha-2 receptors. In dogs, mosapride was as potent as cisapride to stimulate antral and duodenal motility. In most of species including man, mosapride undergoes extensive cleavage to a N-debenzylated metabolite which retains partial 5-HT4 activity but has potent 5-HT3 antagonist activity.
Chemical Properties
White to Off-White Crystalline Solid
Originator
Dainippon (Japan)
Uses
gastroprokinetic agent
Uses
A selective 5-HT4 receptor agonist. Gastroprokinetic.
Definition
ChEBI: Mosapride is a racemate comprising equimolar amounts of (R)- and (S)-mosapride. It is a gastroprokinetic agent which acts on 5-hydroxytryptamine type 4 (5-HT4) receptors in the gastrointestinal plexus, consequently increasing the release of acetylcholine and hence enhancing gastrointestinal motility and gastric emptying. It has a role as a gastrointestinal drug and a serotonergic agonist. It contains a (R)-mosapride and a (S)-mosapride.
brand name
Gasmotin
Hazard
A poison by ingestion.
Safety Profile
A poison by ingestion. When heated to decomposition it emits toxic vapors of NOx, F-, and Cl-.
Mosapride Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29888 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49392 | 58 |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30250 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23555 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 7930 | 58 |
Chongqing Ensky Pharmaceutical Co.,Ltd. | +86-23-86815286 +86-13983794297 | sales@ensky-chemical.com | China | 91 | 58 |
Baoji Guokang Bio-Technology Co., Ltd. | 0917-3909592 13892490616 | gksales1@gk-bio.com | China | 9316 | 58 |
View Lastest Price from Mosapride manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2021-07-13 | Mosapride
112885-41-3
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | ||
2021-07-09 | Mosapride
112885-41-3
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | ||
2021-07-02 | Mosapride
112885-41-3
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
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