LUPENONE
- CAS No.
- 1617-70-5
- Chemical Name:
- LUPENONE
- Synonyms
- LUPENONE;-en-3-one;Lup-20(29);Aids082905;Aids-082905;LUPENONE(RG);18-LUPEN-3-ONE;Lup-20(29)-en-3-one;Lupa-20(30)-ene-3-one;5α-Lup-20(29)-en-3-one
- CBNumber:
- CB3447619
- Molecular Formula:
- C30H48O
- Molecular Weight:
- 424.7
- MDL Number:
- MFCD00083578
- MOL File:
- 1617-70-5.mol
| Product description | Number | Pack Size | Price |
| LUP-20(29)-EN-3-ONE AldrichCPR | R205265 | 1MG | $113 |
| Lupenone | 453973 | 2.5mg | $496 |
| Lupenone | L474840 | 10mg | $595 |
| Lupenone | orb594672 | 10mg | $513.4 |
| Lupenone >98%,Standard References Grade | orb105776 | 20mg | $569.5 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Hazard Codes | Xi |
| HS Code | 29142990 |
LUPENONE price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | R205265 | LUP-20(29)-EN-3-ONE AldrichCPR | 1617-70-5 | 1MG | $113 | 2025-07-31 | Buy |
| Usbiological | 453973 | Lupenone | 1617-70-5 | 2.5mg | $496 | 2021-12-16 | Buy |
| TRC | L474840 | Lupenone | 1617-70-5 | 10mg | $595 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb594672 | Lupenone | 1617-70-5 | 10mg | $513.4 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb105776 | Lupenone >98%,Standard References Grade | 1617-70-5 | 20mg | $569.5 | 2021-12-16 | Buy |
LUPENONE Chemical Properties,Uses,Production
Chemical Properties
White powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from dandelion, bamboo leaves and Adenophora australis.
Uses
Lupenone is a lupane triterpenoid with antioxidant and anticholinesterase activity. It also a potential protein tyrosine phosphatase 1B (PTP1B) inhibitor.
Definition
ChEBI: A natural product found in Cupania cinerea.
in vivo
Lupenone (6, 12, 24 mg/kg/day, gavage for 6 weeks) improves type 2 diabetic nephropathy by regulating NF-κB pathway-mediated inflammation and TGF-β1/Smad/ CTGF-related fibrosis[2].
| Animal Model: | Spontaneous type 2 diabetic nephropathy db/db mouse models[1] |
| Dosage: | 6, 12, 24 mg/kg |
| Administration: | i.g. |
| Result: | Maintained the fasting blood glucose. Reduced glycosylated hemoglobin, insulin, and 24 h proteinuria levels. Regulated changes in biochemical indicators |
IC 50
Trypanosoma
LUPENONE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29850 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 3751 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 | sales@chemnorm.com | CHINA | 2935 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32435 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10237 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
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