ChemicalBook >> CAS DataBase List >>OXIDIZED NIFEDIPINE
OXIDIZED NIFEDIPINE
- CAS No.
- 67035-22-7
- Chemical Name:
- OXIDIZED NIFEDIPINE
- Synonyms
- B 4759;BAY-b-4759;Nifedipine-1;Dehydro Nifedipine;Nifidipine Impurity A;Nitrophenyl nifedipine;Nifedipine impurity A CRS;Nifedipine impurity A (EP);Divalproex Sodium Impurity 1;Azilsartan medoxomil impurity308
- CBNumber:
- CB3505238
- Molecular Formula:
- C17H16N2O6
- Molecular Weight:
- 344.32
- MDL Number:
- MFCD00153847
- MOL File:
- 67035-22-7.mol
- MSDS File:
- SDS
Last updated:2023-06-08 09:02:52
| Melting point | 100-105 °C |
|---|---|
| Boiling point | 443.7±45.0 °C(Predicted) |
| Density | 1.284±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | powder |
| pka | 1.55±0.29(Predicted) |
| color | yellow |
| FDA UNII | OR3W8GT1C8 |
| EPA Substance Registry System | 3,5-Pyridinedicarboxylic acid, 2,6-dimethyl-4-(2-nitrophenyl)-,3,5-dimethyl ester (67035-22-7) |
OXIDIZED NIFEDIPINE price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | UC167 | Oxidized Nifedipine powder, ~95% (HPLC) | 67035-22-7 | 5mg | $469 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1463600 | Nifedipine Nitrophenylpyridine Analog United States Pharmacopeia (USP) Reference Standard | 67035-22-7 | 25mg | $1530 | 2024-03-01 | Buy |
| Cayman Chemical | 23229 | Dehydro Nifedipine ≥98% | 67035-22-7 | 1mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 23229 | Dehydro Nifedipine ≥98% | 67035-22-7 | 5mg | $193 | 2024-03-01 | Buy |
| Sigma-Aldrich | UC167 | Oxidized Nifedipine powder, ~95% (HPLC) | 67035-22-7 | 10mg | $861 | 2024-03-01 | Buy |
OXIDIZED NIFEDIPINE Chemical Properties,Uses,Production
Description
Dehydro nifedipine is an active metabolite of nifedipine , a calcium channel blocker present in formulations used to treat hypertension and angina. Dehydro nifedipine is formed when nifedipine is metabolized by the cytochrome P450 (CYP) isomers CYP3A4 and CYP3A5. Dehydro nifedipine inhibits glucose uptake in PC-12 cells with an IC50 value of 130 μM.
Chemical Properties
Pale Yellow Solid
Uses
Oxidized nifedipine has been used for apoptotic signaling studies in dopaminergic neurons.
Uses
The main Nifedipine metabolite in human plasma
Definition
ChEBI: Dehydronifedipine is a phenylpyridine.
Biochem/physiol Actions
CYP3A4 nifedipine metabolite. Nifedipine (parent compound) is an antianginal and antihypertensive agent.
OXIDIZED NIFEDIPINE Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 113)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Accela ChemBio Inc. | (+1)-858-699-3322 | info@accelachem.com | United States | 19965 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14336 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81148696 +8615536356810 | 1047@dideu.com | China | 3408 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23556 | 58 |
| CR Corporation Lomited | fred.wen@crcorporation.cn | CHINA | 12069 | 58 | |
| Hangzhou Huarong Pharm Co., Ltd. | 571-86758373 +8613588754946 | sales@huarongpharm.com | CHINA | 3149 | 58 |
| sgtlifesciences pvt ltd | +8617013299288 | dj@sgtlifesciences.com | China | 12382 | 58 |
| Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
| China National Standard Pharmaceutical Corporation Limited | +8615391658522 | overseasales@yongstandards.com | China | 11927 | 58 |
View Lastest Price from OXIDIZED NIFEDIPINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-12-29 | Oxidized Nifedipine
67035-22-7
|
US $0.10 / KG | 1KG | 99.0% | 1000 tons | Shaanxi Dideu Medichem Co. Ltd |
-
- Oxidized Nifedipine
67035-22-7
- US $0.10 / KG
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
67035-22-7(OXIDIZED NIFEDIPINE)Related Search:
Nifedipine
METHYL 2-(O-NITROBENZYLIDENE)-ACETOACETATE
Methyl 3-aminocrotonate
2,6-Ntp
Dehydro Nifedipine N-Oxide
diethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Nifedipine Impurity J
Hydroxydehydro Nifedipine Carboxylate
methyl 2,4-bis{2-nitrophenyl}-6-methyl-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate
Nifedipine Impurity 9
1of4
Nifedipine Nitrophenylpyridine Analog
dimethyl 2,6-dimethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxylate
dimethyl2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylate
2,6-Dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3,5-Dimethyl Ester
B 4759
Dehydro Nifedipine
2,6-Dimethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxylic acid dimethyl ester
4-(2-Nitrophenyl)-2,6-dimethylpyridine-3,5-dicarboxylic acid dimethyl ester
BAY-b-4759
Nitrophenyl nifedipine
Nifedipine-1
Dimethyl 2,6-Dimethyl-4-(2-nitrophenyl)-3,5-pyridined
Nifedipine Impurity Ⅰ:2,6-Dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3,5-Dimethyl Ester
2,6-Dimethyl-4-(2′-nitrophenyl)-3,5-pyridinecarboxylic acid dimethyl ester, Oxidized Nifedipine
Divalproex Sodium Impurity 1
Nifedipine impurity A (EP)
Dimethyl 4-(2-nitrophenyl)-2,6-dimethylpyridine-3,5-dicarboxylate
Nifedipine Impurity Ⅰ（Dimethyl 2,6-Dimethyl-4-(2-Nitrophenyl)pyridine-3,5-Dicarboxylate）
Nifedipine impurity A CRS
Dimethyl 2,6-Dimethyl-4-(2-nitrophe
Nifedipine EP Impurity A/Dehydro Nifedipine
3,5-Pyridinedicarboxylic acid, 2,6-dimethyl-4-(2-nitrophenyl)-, 3,5-dimethyl ester
Nifidipine Impurity A
Nifedipine EP Impurity A (Nifedipine nitrophenylpyridine analogue)
Azilsartan medoxomil impurity308
DehydronifedipineQ: What is
Dehydronifedipine Q: What is the CAS Number of
Dehydronifedipine Q: What is the storage condition of
Dehydronifedipine Q: What are the applications of
Dehydronifedipine
Nifedipine Impurity Ⅰ:2,6-Dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3,5-Dimethyl Ester
Nifedipine nitrophenylpyridine Analogue
dimethyl 2,6-dimethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxylate (nitrophenylpyridine analogue)
_x000b_Dimethyl 2,6-Dimethyl-4-(2-nitrophenyl)-3,5-pyridined
Nifedipine EP impurity A
Dimethyl 2,6-dimethyl-4-(2-nitrophenyl)pyridine-3,5- dicarboxylate (nitrophenylpyridine analogue)
67035-22-7
34432
Intermediates & Fine Chemicals
Metabolites & Impurities
Pharmaceuticals
Various Metabolites and Impurities