ChemicalBook >> CAS DataBase List >>4-Nitrophthalimide


Chemical Name:
5-NITROISOINDOLINE-1,3-DIONE;5-NITROPHTHALIMIDE;AKOS B028733;4-Nitrophtalimide;4-nitro-phthalimid;4-NITROPHTHALIMIDE;4-Nirtophthalimide;P-NITRO-PHTHALIMIDE;PHTHALIMIDE, 4-NITRO-;4-Nitrophthalimide>
Molecular Formula:
Molecular Weight:
MDL Number:
MOL File:
Modify Date:
2022-08-15 17:36:34

4-Nitrophthalimide Properties

Melting point 206 °C
Boiling point 328.09°C (rough estimate)
Density 1.5513 (rough estimate)
refractive index 1.4900 (estimate)
storage temp. Sealed in dry,Room Temperature
pka 7.79±0.20(Predicted)
color Yellow powder
Water Solubility <0.01 g/100 mL at 18 ºC
BRN 180224
Stability Stable. Combustible. Incompatible with moisture, water, strong oxidising agents, strong bases.
CAS DataBase Reference 89-40-7(CAS DataBase Reference)
EWG's Food Scores 1
NIST Chemistry Reference 4-Nitro-phthalimide(89-40-7)
EPA Substance Registry System 4-Nitrophthalimide (89-40-7)


Risk and Safety Statements

Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  37/39-26-36-24/25
WGK Germany  3
RTECS  TI5625000
Hazard Note  Irritant
HS Code  29251900
Toxicity mmo-sat 333 mg/plate EMMUEG 11(Suppl 12),1,88

4-Nitrophthalimide price More Price(30)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 332097 4-Nitrophthalimide 98% 89-40-7 5g $67.9 2022-05-15 Buy
Sigma-Aldrich 332097 4-Nitrophthalimide 98% 89-40-7 25g $286 2022-05-15 Buy
TCI Chemical N0247 4-Nitrophthalimide >98.0%(HPLC)(T) 89-40-7 25g $28 2022-04-27 Buy
TCI Chemical N0247 4-Nitrophthalimide >98.0%(HPLC)(T) 89-40-7 500g $272 2022-04-27 Buy
Alfa Aesar A12040 4-Nitrophthalimide, 98% 89-40-7 5g $37 2022-04-27 Buy
Product number Packaging Price Buy
332097 5g $67.9 Buy
332097 25g $286 Buy
N0247 25g $28 Buy
N0247 500g $272 Buy
A12040 5g $37 Buy

4-Nitrophthalimide Chemical Properties,Uses,Production

Chemical Properties

slight yellow powder


4-Nitrophthalimide is used as intermediate of organic synthesis and fluorescent dyes, it can be used to produce azo dyes, luminol, etc. It can also be used to prepare 4-nitrophthalonitrile, 5-cyanophthalide and other drug intermediates.


4-Nitrophthalimide is synthesized from phthalimide by nitration. Cool the fuming nitric acid to below 5°C, slowly add concentrated sulfuric acid dropwise, and control the temperature to 10-13°C. Plus phthalimide. Leave at room temperature overnight. Then, it was poured into ice water with stirring, and the precipitate was precipitated below 20°C. Filter, wash with water, dry, and then recrystallize from ethanol to obtain 4-nitrophthalimide with a yield of 60%.

General Description

Yellow powder.

Air & Water Reactions

4-Nitrophthalimide can be hydrolyzed. . Insoluble in water.

Reactivity Profile

A nitrated amine. Amines are combustible. The combustion of amines yields noxious NOx. REACTIVITY - Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. Aromatic nitro compounds range from slight to strong oxidizing agents. If mixed with reducing agents, including hydrides, sulfides and nitrides, they may begin a vigorous reaction that culminates in a detonation. The aromatic nitro compounds may explode in the presence of a base such as sodium hydroxide or potassium hydroxide even in the presence of water or organic solvents. The explosive tendencies of aromatic nitro compounds are increased by the presence of multiple nitro groups.

Fire Hazard

Flash point data for 4-Nitrophthalimide are not available, however 4-Nitrophthalimide is probably combustible.

Safety Profile

Mutation data reported. Whenheated to decomposition it emits toxic vapors of NOx.

Global( 336)Suppliers
Supplier Tel Email Country ProdList Advantage
Frapp's ChemicalNFTZ Co., Ltd.
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Capot Chemical Co.,Ltd.
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View Lastest Price from 4-Nitrophthalimide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2022-02-25 4-Nitrophthalimide
US $25.12 / Kg/Drum 25Kg/Drum 99.00%HPLC 10tons/month Asia Chem I and E (Jiangsu) Co Ltd
2021-12-01 4-Nitrophthalimide
US $10.70 / Kg/Bag 10g 99% 10000kg Hebei Crovell Biotech Co Ltd
2021-08-17 4-Nitrophthalimide
US $1.00 / KG 1KG 99% 10 mt Hebei Guanlang Biotechnology Co., Ltd.
AKOS B028733 5-NITRO-1,3-DIHYDRO-2H-ISOINDOL-1,3-DIONE 5-NITRO-1H-ISOINDOLE-1,3(2H)-DIONE 4 - nitro phthalates forMyl aMine 5-NITROISOINDOLE-1,3-DIONE 4-NITRO-1,2-BENZENE DICARBOXYLIC ACID, IMIDE 4-NITROPHTHALIMIDE PHTHALIMIDE, 4-NITRO- P-NITRO-PHTHALIMIDE 1H-Isoindole-1,3(2H)-dione, 5-nitro- 4-nitro-phthalimid 5-nitro-1h-isoindole-3(2h)-dione 4-Nirtophthalimide 5-Nitro-2H-isoindole-1,3-dione 4-Nitrophthalimide,98% 4-Nitrophtalimide 4-Nitrophthalimide> 4-Nitrophthalimide ISO 9001:2015 REACH 4-NITRO PHTHALIMIDE/4-Nitrophthalimide 5-NITROPHTHALIMIDE 5-NITROISOINDOLINE-1,3-DIONE 89-40-7 C8H4N2O4 Organic Building Blocks Cyclic Imides Building Blocks Carbonyl Compounds Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts N Stains and Dyes Stains&Dyes, A to