4-Nitrothiophenol
- CAS No.
- 1849-36-1
- Chemical Name:
- 4-Nitrothiophenol
- Synonyms
- 4-NITROBENZENETHIOL;P-NITROTHIOPHENOL;4-NITROTHIOPHENOL;P-NITROBENZOLTHIOL;4-Nitrobenzolthiol;4-nitro-benzenethio;p-nitro-benzenethio;P-NITROBENZENETHIOL;4-nitrothiophenolate;PARA-NITROTHIOPHENOL
- CBNumber:
- CB3682452
- Molecular Formula:
- C6H5NO2S
- Molecular Weight:
- 155.17
- MDL Number:
- MFCD00007343
- MOL File:
- 1849-36-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 4-Nitrothiophenol technical grade, 80% | N27209 | 5g | $121 |
| 4-Nitrothiophenol technical grade, 80% | N27209 | 25g | $422 |
| 4-Nitrobenzenethiol >95.0%(GC)(T) | N0146 | 5g | $51 |
| 4-Nitrobenzenethiol >95.0%(GC)(T) | N0146 | 25g | $175 |
| 4-Nitrothiophenol(ContainsDimer) | N565520 | 1g | $45 |
| More product size | |||
| Melting point | 72-77 °C (lit.) |
|---|---|
| Boiling point | 281.9±23.0 °C(Predicted) |
| Density | 1.357 (estimate) |
| refractive index | 1.5380 (estimate) |
| storage temp. | 2-8°C |
| solubility | Chloroform (Sparingly), Methanol (Slightly) |
| pka | 4.68±0.10(Predicted) |
| form | Crystalline Powder and/or Chunks |
| color | Yellow |
| Water Solubility | Partly soluble in water and chloroform. |
| Sensitive | Stench |
| BRN | 606924 |
| InChI | 1S/C6H5NO2S/c8-7(9)5-1-3-6(10)4-2-5/h1-4,10H |
| InChIKey | AXBVSRMHOPMXBA-UHFFFAOYSA-N |
| SMILES | [O-][N+](=O)c1ccc(S)cc1 |
| CAS DataBase Reference | 1849-36-1(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | QL9H28763R |
| NIST Chemistry Reference | Benzenethiol, 4-nitro-(1849-36-1) |
| EPA Substance Registry System | 4-Nitrothiophenol (1849-36-1) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| RIDADR | UN 3335 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | DC1850000 | |||||||||
| F | 9-13-23 | |||||||||
| Hazard Note | Harmful/Irritant/Stench | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29309090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
4-Nitrothiophenol price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | N27209 | 4-Nitrothiophenol technical grade, 80% | 1849-36-1 | 5g | $121 | 2026-04-30 | Buy |
| Sigma-Aldrich | N27209 | 4-Nitrothiophenol technical grade, 80% | 1849-36-1 | 25g | $422 | 2026-04-30 | Buy |
| TCI Chemical | N0146 | 4-Nitrobenzenethiol >95.0%(GC)(T) | 1849-36-1 | 5g | $51 | 2026-04-30 | Buy |
| TCI Chemical | N0146 | 4-Nitrobenzenethiol >95.0%(GC)(T) | 1849-36-1 | 25g | $175 | 2026-04-30 | Buy |
| TRC | N565520 | 4-Nitrothiophenol(ContainsDimer) | 1849-36-1 | 1g | $45 | 2021-12-16 | Buy |
4-Nitrothiophenol Chemical Properties,Uses,Production
Chemical Properties
yellow crystalline powder and/or chunks
Uses
4-Nitrothiophenol has been used in the synthesis of dual emission fluorescent probe for the differential sensing of of glutathione (GSH) and cysteine/homocysteine (Cys/Hcy). pNTP can also be used to synthesize diaryl thioethers via copper-catalyzed C-S coupling reaction.
Research
A 4-nitrothiophenol (4-NTP, Ar-NO2) modified electrode was prepared by dipping a gold electrode into a 4-NTP/dichloromethane solution (self-assembly method). The redox response of the electrode depended on the reduction stages of the nitro group in the 4-NTP molecule. When the 4-NTP on the electrode was partially reduced to 4-hydroxylaminothiophenol (Ar-NHOH) at -0.2 to -0.3 V vs SCE (the potential depends on the pH of the electrolyte solution), the electrode showed a pair of redox responses in an acidic aqueous solution. The responses are attributed to the redox cycling between 4-nitrosothiophenol (Ar-NO) and Ar-NHOH with two-electron and two-proton transfer.
Underpotential deposition (UPD) in electrochemistry can be used to form heterometal deposits on substrates at a monolayer level, altering the surface characteristics. For a monolayer of 4-nitrothiophenol (4-NTP) on a roughened Au substrate, the reduction and dimerization to 4,4′-dimercaptoazobenzene (DMAB) were monitored under conditions of Ag UPD using electrochemical surface-enhanced Raman spectroscopy (EC-SERS). Formation of DMAB was enhanced on the Ag surface deposited via UPD between the Au substrate and the 4-NTP layer. The structures of the 4-NTP layer and the plasmonic surface remained intact during Ag UPD[1-2].
References
[1] Misun Hong. "Underpotential Deposition of Silver on Gold for Surface Catalysis of Plasmon-Enhanced Reduction of 4-Nitrothiophenol." The Journal of Physical Chemistry C 125 30 (2021): 16569–16575.
[2] Hiromori Tsutsumi. "Electrochemical Behavior of a 4-Nitrothiophenol Modified Electrode Prepared by the Self-Assembly Method." Journal of Colloid and Interface Science 171 2 (1995): Pages 505-511.
[3] Jan Kozisek . "Plasmon-driven substitution of 4–mercaptophenylboronic acid to 4-nitrothiophenol monitored by surface-enhanced Raman spectroscopy." Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 319 (2024): Article 124523.
[4] Satish C. Agarwal. “Reaction of epoxides with 4-nitrothiophenol. Its possible application for trapping and characterization of epoxides.” Environmental Science and Technology 14 10 (1980): 1249–1253.
4-Nitrothiophenol Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13843 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21590 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29819 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| Richest Group Ltd | 18017061086 | oled@richest-group.com | CHINA | 5600 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10236 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| HONG KONG IPURE BIOLOGY CO.,LIMITED | 86 18062405514 18062405514 | ada@ipurechemical.com | CHINA | 3461 | 58 |
View Lastest Price from 4-Nitrothiophenol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-03-20 | 4-NITROTHIOPHENOL
1849-36-1
|
US $0.00-0.00 / KG | 1KG | 99% | 20 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2024-04-28 | 4-NITROTHIOPHENOL
1849-36-1
|
US $100.00-30.00 / kg | 1kg | 99.93% | 1000kg per week | Ouhuang Engineering Materials (Hubei) Co., Ltd | |
 |
2019-07-11 | 4-NITROTHIOPHENOL
1849-36-1
|
US $1.00 / KG | 1KG | 99% | 25kg | Career Henan Chemical Co |
-
- 4-NITROTHIOPHENOL
1849-36-1
- US $0.00-0.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 4-NITROTHIOPHENOL
1849-36-1
- US $100.00-30.00 / kg
- 99.93%
- Ouhuang Engineering Materials (Hubei) Co., Ltd
-
- 4-NITROTHIOPHENOL
1849-36-1
- US $1.00 / KG
- 99%
- Career Henan Chemical Co
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