Geldanamycin-FITC
- CAS No.
- 2969156-01-0
- Chemical Name:
- Geldanamycin-FITC
- Synonyms
- Geldanamycin-FITC
- CBNumber:
- CB39272847
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Geldanamycin-FITC Chemical Properties,Uses,Production
Description
Geldanamycin-FITC is a novel geldanamycin fluorescent probe1?that may be used in a fluorescence polarization assay for HSP-90 inhibitors.2,3?May also be used for detection of cell surface HSP-90 and for other applications. Fluorescent geldanamycin probes have been used to characterize geldanamycin drug-target interactions for effective translation of?in vitro?pharmacology to cellular and?in vivo?efficacy.4
Uses
Geldanamycin-FITC is a novel geldanamycin fluorescent probe. Fluorescent geldanamycin probes have been used to characterize geldanamycin drug-target interactions for effective translation of in vitro pharmacology to cellular and in vivo efficacy.
References
1) Llauger-Bufi?et al. (2003),?Synthesis of novel fluorescent probes for the molecular chaperone Hsp90;? Bioorg. Med. Chem. Lett.,?13?3975 2) Kim?et al. (2004),?Development of a fluorescent polarization assay for the molecular chaperone Hsp90;? J. Biomol. Screen.,?9?375 3) Austin?et al. (2012),?Fragment screening using capillary electrophoresis (Defrag) for hit identification of heat shock protein 90 ATPase inhibitors;? J. Biomol. Screen.,?17?868 4) Gooljarsingh?et al. (2006),?A biochemical rationale for the anticancer effects of Hsp90 inhibitors: slow, tight binding inhibition by geldanamycin and its analogues;? Proc. Natl. Acad. Sci. USA,?103?7625
Geldanamycin-FITC Preparation Products And Raw materials
Raw materials
Preparation Products
Geldanamycin-FITC Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Artis Biotech Co. Ltd. | 19138486554 18582380095 | sales@artisbio.com | China | 2804 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 29778 | 58 |
| Supplier | Advantage |
|---|---|
| Artis Biotech Co. Ltd. | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 58 |