2-hydroxy-6-methyl-1H-quinolin-4-one
- CAS No.
- 1677-44-7
- Chemical Name:
- 2-hydroxy-6-methyl-1H-quinolin-4-one
- Synonyms
- 6-Methylquinoline-2,4-diol;4-Hydroxy-6-methyl-2-quinolone;6-Methyl-2,4-dihydroxyquinoline;4,6-Dihydroxy-2-methylquinoline;2-hydroxy-6-methyl-1H-quinolin-4-one;4-Hydroxy-6-methyl-1H-quinolin-2-one;2(1H)-Quinolinone, 4-hydroxy-6-methyl-
- CBNumber:
- CB41456167
- Molecular Formula:
- C10H9NO2
- Molecular Weight:
- 175.18
- MDL Number:
- MFCD00227473
- MOL File:
- 1677-44-7.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 6-Methylquinoline-2,4-diol | M341805 | 100mg | $90 |
| 6-Methylquinoline-2,4-diol | M341805 | 50mg | $45 |
| 6-Methyl-2,4-dihydroxyquinoline 95+% | 073413 | 1g | $838 |
| 6-Methyl-2,4-dihydroxyquinoline 95+% | 073413 | 5g | $2250 |
| 6-Methyl-2,4-dihydroxyquinoline | W3646 | 250mg | $298 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
2-hydroxy-6-methyl-1H-quinolin-4-one price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | M341805 | 6-Methylquinoline-2,4-diol | 1677-44-7 | 100mg | $90 | 2021-12-16 | Buy |
| TRC | M341805 | 6-Methylquinoline-2,4-diol | 1677-44-7 | 50mg | $45 | 2021-12-16 | Buy |
| Matrix Scientific | 073413 | 6-Methyl-2,4-dihydroxyquinoline 95+% | 1677-44-7 | 1g | $838 | 2021-12-16 | Buy |
| Matrix Scientific | 073413 | 6-Methyl-2,4-dihydroxyquinoline 95+% | 1677-44-7 | 5g | $2250 | 2021-12-16 | Buy |
| AK Scientific | W3646 | 6-Methyl-2,4-dihydroxyquinoline | 1677-44-7 | 250mg | $298 | 2021-12-16 | Buy |
2-hydroxy-6-methyl-1H-quinolin-4-one Chemical Properties,Uses,Production
Synthesis
106-49-0
105-53-3
1677-44-7
In a dry three-necked flask, p-toluidine (5.0 g, 46.7 mmol), diethyl malonate (14 mL, 93.3 mmol) and polyphosphoric acid (22.5 mL, 140 mmol) were added sequentially. The reaction mixture was stirred at 150 °C for 3 hours. Upon completion of the reaction, the reaction system was cooled to room temperature, 500 mL of ice water was slowly added, and the pH was adjusted to 5-6 with alkali. the resulting yellow solid product was collected by filtration. The solid was dissolved in an appropriate amount of sodium hydroxide solution and filtered again to yield 7.5 g of 6-methyl-2,4-dihydroxyquinoline as a yellow solid in 92% yield.
References
[1] Patent: CN107098901, 2017, A. Location in patent: Paragraph 0082; 0083; 0084; 0085
[2] British Journal of Pharmacology, 2015, vol. 172, # 5, p. 1195 - 1221
[3] European Journal of Medicinal Chemistry, 2010, vol. 45, # 10, p. 4467 - 4472
2-hydroxy-6-methyl-1H-quinolin-4-one Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53802 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Chemwill Asia Co.,Ltd. | 86-21-51086038 | chemwill_asia@126.com | CHINA | 23912 | 58 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14101 | 59 |
| China Langchem Inc. | 0086-21-58956006 | China | 7811 | 57 | |
| NovoChemy Ltd. | 021-31261262/ 49 (0)17662837245 | sales@novochemy.com | Germany | 6328 | 58 |
