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CORTISOL-9,11,12,12-D4

CAS No.
73565-87-4
Chemical Name:
CORTISOL-9,11,12,12-D4
Synonyms
Hycort-d4;Acticort-d4;Hycortol-d4;Texacort-d4;TiMocort-d4;Cortisol-d4;DerMacort-d4;Hydrocortal-d4;[2H4]-Cortisol;Deuterated cortisol
CBNumber:
CB4234270
Molecular Formula:
C21H26D4O5
Molecular Weight:
366.49
MDL Number:
MFCD00144010
MOL File:
73565-87-4.mol
Last updated:2023-05-18 11:31:18

CORTISOL-9,11,12,12-D4 Properties

Melting point 211-214 °C
Flash point 9℃
storage temp. -20°C Freezer
solubility DMSO (Slightly), Ethanol (Slightly, Heated), Methanol (Slightly, Heated), Water
form Solid
color White to Off-White

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS08
Signal word  Warning
Hazard statements  H361
Precautionary statements  P201-P202-P280-P308+P313-P405-P501
Hazard Codes  Xn,T,F
Risk Statements  63-39/23/24/25-23/24/25-11
Safety Statements  36/37-45-16-7
RIDADR  UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany  3

CORTISOL-9,11,12,12-D4 price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C-113 Cortisol-D4 (9,11,12, 12-D4) solution 100?μg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant? 73565-87-4 1mL $474 2024-03-01 Buy
Sigma-Aldrich 705594 Hydrocortisone-9,11,12,12-d4 98 atom % D, 98% (CP) 73565-87-4 5mg $921 2024-03-01 Buy
Sigma-Aldrich 705594 Hydrocortisone-9,11,12,12-d4 98 atom % D, 98% (CP) 73565-87-4 10mg $1610 2024-03-01 Buy
Cayman Chemical 26500 Hydrocortisone-d4 73565-87-4 500μg $93 2024-03-01 Buy
Cayman Chemical 26500 Hydrocortisone-d4 73565-87-4 5mg $684 2024-03-01 Buy
Product number Packaging Price Buy
C-113 1mL $474 Buy
705594 5mg $921 Buy
705594 10mg $1610 Buy
26500 500μg $93 Buy
26500 5mg $684 Buy

CORTISOL-9,11,12,12-D4 Chemical Properties,Uses,Production

Description

Hydrocortisone-d4 is intended for use as an internal standard for the quantification of hydrocortisone/cortisol by GC- or LC-MS. Cortisol, known as hydrocortisone when used as a therapeutic, is a glucocorticoid produced by the adrenal cortex in response to adrenocorticotropic hormone (ACTH). It is an agonist at the mineralocorticoid receptor (MR) and the glucocorticoid receptor (GR), with an approximately 6- to 10-fold greater affinity for MR. Cortisol production is increased during periods of stress, and it is a major effector molecule in the hypothalamic-pituitary-adrenal axis (HPA) stress response. Cortisol levels increase with age and are often elevated in major depressive disorder, certain forms of hypertension, and Parkinson''s disease.

Chemical Properties

White Solid

Uses

Anti-inflammatory hormone

Uses

Labelled Cortisol (H714615). Cortisol, or Hydrocortisone, is a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism.

General Description

Cortisol, also known as hydrocortisone, is a glucocorticoid produced by the adrenal gland. This stable labeled internal standard is suitable for quantitation of cortisol levels in whole blood by LC-MS/MS for newborn screening of congenital adrenal hyperplasia (CAH) and in serum or plasma by LC-MS/MS for determination of several diseases including Cushing′s syndrome, Addison′s disease, and Sheehan′s syndrome.

CORTISOL-9,11,12,12-D4 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 49)Suppliers
Supplier Tel Email Country ProdList Advantage
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
SIMSON PHARMA LIMITED
+91-8291074273 k.das@simsonpharma.com India 228 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 52927 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32344 50
Clearsynth Labs Limited +91-22-26355700 info@clearsynth.com India 9685 58
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Artis Biotech Co. Ltd. 19138486554 18582380095 sales@artisbio.com China 2820 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9709 58
Shenzhen Newcore Chemical Technology Co., Ltd. 13612807752 ncchemical@163.com China 290 55

View Lastest Price from CORTISOL-9,11,12,12-D4 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Hydrocortisone D4 pictures 2023-05-27 Hydrocortisone D4
73565-87-4
US $0.00-0.00 / mg 1mg 96% 50 mg Simson Pharma limited
17-Hydroxycorticosterone-9,11,12,12-d4, Cortisol-9,11,12,12-d4, Hydrocortisone-9,11,12,12-d4, Kendall's compound F (9,11,12,12-d4), Reichstein's substance M (9,11,12,12-d4), 4-Pregnene-11β,17α,21-triol-3,20-dione-d4 (9,11,12,12-d4), 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione-d4 (9,11,12,12-d4) CORTISOL-9,11,12,12-D4 HYDROCORTISONE (9,11,12,12-D4) Cortisol-D4 (9,11,12,12-D4) (11β)-11,17,21-Trihydroxy-pregn-4-ene-3,20-dione-d4 11β-Hydroxycortisone-d4 17-Hydroxycorticosterone-d4 Acticort-d4 DerMacort-d4 Hycort-d4 Hycortol-d4 Hydrocortal-d4 Pregn-4-ene-3,20-dione-d4 Texacort-d4 TiMocort-d4 Cortisol-d4 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione-D4 Cortisol-[D4] (CertiMass solution) Cortisol-D4 (9,11,12, 12-D4) solution Cortisol-D4 (9,11,12,12-D4) solution Hydrocortisone-9,11,12,12-D4 solution Deuterated cortisol Deuterated hydrocortisone Pregn-4-ene-3,20-dione-9,11,12,12-d4,11,17,21-trihydroxy-, (11b)- 4-Pregnene-11β,17α,21-triol-3,20-dione-D4 (8S,10R,11S,13S)-9,11,12,12-tetradeuterio-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,14,15,16-octahydrocyclopenta[a]phenanthren-3-one Cortisol-[d4] (Solution) [2H4]-Cortisol Hydrocortisone D4Q: What is Hydrocortisone D4 Q: What is the CAS Number of Hydrocortisone D4 Q: What is the storage condition of Hydrocortisone D4 Q: What are the applications of Hydrocortisone D4 Hydrocortisone-d4 (Cortisol-d4) Pregn-4-ene-3,20-dione-9,11,12,12-d4, 11,17,21-trihydroxy-, (11β)- Cortisol-9,11,12,12-d? 73565-87-4 C21H26D4O5 C21D4H26O5 C21H26D4O4 Steroids & Hormones - 13C & 2H Intermediates & Fine Chemicals Isotope Labelled Compounds Pharmaceuticals Steroids