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CAY10576

CAY10576 Structure
CAY10576 structure
CAS No.
862812-98-4
Chemical Name:
CAY10576
Synonyms
CAY10576;IKK-3 Inhibitor;GSK-319347A,GSK319347A;GSK319347A, 10 mM in DMSO;IKK-epsilon Kinase Inhibitor II, Inhibitor of IkappaB kinases (IKK);5-(5,6-dimethoxybenzimidazol-1-yl)-3-[(2-methylsulfonylphenyl)methoxy]thiophene-2-carbonitrile;5-(5,6-Dimethoxy-1H-benzimidazol-1-yl)-3-[[2-(methylsulfonyl)phenyl]methoxy]-2-thiophenecarbonitrile;2-Thiophenecarbonitrile, 5-(5,6-diMethoxy-1H-benziMidazol-1-yl)-3-[[2-(Methylsulfonyl)phenyl]Methoxy]-
CBNumber:
CB42454234
Molecular Formula:
C22H19N3O5S2
Molecular Weight:
469.53
MDL Number:
MFCD10567700
MOL File:
862812-98-4.mol
MSDS File:
SDS
Last updated:2025-06-12 13:02:17
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CAY10576 Properties

Boiling point 744.4±70.0 °C(Predicted)
Density 1.39±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 45 mg/mL (95.84 mM; Need ultrasonic)
form Powder
pka 3.09±0.10(Predicted)
color Light yellow to yellow
UNSPSC Code 12352200

CAY10576 price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10011249 CAY10576 ≥95% 862812-98-4 1mg $45 2024-03-01 Buy
Cayman Chemical 10011249 CAY10576 ≥95% 862812-98-4 5mg $198 2024-03-01 Buy
Cayman Chemical 10011249 CAY10576 ≥95% 862812-98-4 10mg $351 2024-03-01 Buy
Cayman Chemical 10011249 CAY10576 ≥95% 862812-98-4 50mg $1528 2024-03-01 Buy
TRC G797610 GSK319347A 862812-98-4 50mg $1010 2021-12-16 Buy
Product number Packaging Price Buy
10011249 1mg $45 Buy
10011249 5mg $198 Buy
10011249 10mg $351 Buy
10011249 50mg $1528 Buy
G797610 50mg $1010 Buy

CAY10576 Chemical Properties,Uses,Production

Uses

GSK 319347A is a potent and selective IKKε kinase inhibitor.

Definition

ChEBI: 5-(5,6-dimethoxy-1-benzimidazolyl)-3-[(2-methylsulfonylphenyl)methoxy]-2-thiophenecarbonitrile is a member of benzimidazoles.

Biological Activity

Cell permeable: no', 'Primary Target
IKK-3', 'Product competes with ATP.', 'Reversible: no', 'Target IC50: 40 nM against IKK-3 (IKK-ε)

IC 50

TBK1: 93 nM (IC50); IKK-ε: 469 nM (IC50); IKK2: 790 nM (IC50)

storage

Store at -20°C

CAY10576 Preparation Products And Raw materials

Raw materials

Preparation Products

CAY10576 Suppliers

Global( 53)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+17819995354 marketing@targetmol.com United States 32372 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30230 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
Aladdin Scientific 		tp@aladdinsci.com United States 57505 58
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4861 58
SPIRO PHARMA eric_feng1954@126.com China 9248 55
Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847; 18021002903 3008007409@qq.com China 71826 60
Shanghai Rechem science Co., Ltd. 021-31433387 15618786686 sales@rechemscience.com China 2967 58
Musechem +1-800-259-7612 info@musechem.com United States 4660 60
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11218 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Career Henan Chemica Co 		58
InvivoChem 		58
Aladdin Scientific 		58
MedChemexpress LLC 58
SPIRO PHARMA 55
Shanghai YuanYe Biotechnology Co., Ltd. 60
Shanghai Rechem science Co., Ltd. 58
Musechem 60
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58

View Lastest Price from CAY10576 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
GSK319347A pictures 2025-06-12 GSK319347A
862812-98-4
 US $67.00-268.00 / mg 98.42% 10g TargetMol Chemicals Inc.
  • GSK319347A pictures
  • GSK319347A
    862812-98-4
  • US $67.00-268.00 / mg
  • 98.42%
  • TargetMol Chemicals Inc.

862812-98-4(CAY10576)Related Search:

CAY10576
CAY10576 IKK-3 Inhibitor 2-Thiophenecarbonitrile, 5-(5,6-diMethoxy-1H-benziMidazol-1-yl)-3-[[2-(Methylsulfonyl)phenyl]Methoxy]- 5-(5,6-Dimethoxy-1H-benzimidazol-1-yl)-3-[[2-(methylsulfonyl)phenyl]methoxy]-2-thiophenecarbonitrile 5-(5,6-dimethoxybenzimidazol-1-yl)-3-[(2-methylsulfonylphenyl)methoxy]thiophene-2-carbonitrile GSK-319347A,GSK319347A IKK-epsilon Kinase Inhibitor II, Inhibitor of IkappaB kinases (IKK) GSK319347A, 10 mM in DMSO 862812-98-4