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ChemicalBook >> CAS DataBase List >>7-[(2-Bromo-5-chlorophenyl)methoxy]-3,4-dihydro-1(2H)-naphthalenone

7-[(2-Bromo-5-chlorophenyl)methoxy]-3,4-dihydro-1(2H)-naphthalenone

7-[(2-Bromo-5-chlorophenyl)methoxy]-3,4-dihydro-1(2H)-naphthalenone Structure
7-[(2-Bromo-5-chlorophenyl)methoxy]-3,4-dihydro-1(2H)-naphthalenone structure
CAS No.
1378388-19-2
Chemical Name:
7-[(2-Bromo-5-chlorophenyl)methoxy]-3,4-dihydro-1(2H)-naphthalenone
Synonyms
CL122;7-(2-bromo-5-chlorobenzyloxy)-1-naphthalenone;7-(2-bromo-5-chlorobenzyloxy)-3,4-dihydronaphthalene-1(2H)-one;7-((2-Bromo-5-chlorobenzyl)oxy)-3,4-dihydronaphthalen-1(2H)-one;7-[(2-Bromo-5-chlorophenyl)methoxy]-3,4-dihydro-1(2H)-naphthalenone;1(2H)-Naphthalenone, 7-[(2-bromo-5-chlorophenyl)methoxy]-3,4-dihydro-
CBNumber:
CB42717199
Molecular Formula:
C17H14BrClO2
Molecular Weight:
365.65
MDL Number:
MOL File:
1378388-19-2.mol
Last updated:2025-07-24 18:13:47
Product description Number Pack Size Price
7-((2-Bromo-5-chlorobenzyl)oxy)-3,4-dihydronaphthalen-1(2H)-one 0458DU 1g $87
7-((2-Bromo-5-chlorobenzyl)oxy)-3,4-dihydronaphthalen-1(2H)-one 0458DU 25g $320
7-((2-bromo-5-chlorobenzyl)oxy)-3,4-dihydronaphthalen-1(2H)-one 97% CM141643 5g $374
7-((2-Bromo-5-chlorobenzyl)oxy)-3,4-dihydronaphthalen-1(2H)-one 97% CD12147467 5g $396
7-((2-Bromo-5-chlorobenzyl)oxy)-3,4-dihydronaphthalen-1(2H)-one 97% A163700 100g $479
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7-[(2-Bromo-5-chlorophenyl)methoxy]-3,4-dihydro-1(2H)-naphthalenone Properties

Boiling point 489.4±45.0 °C(Predicted)
Density 1.488±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338

7-[(2-Bromo-5-chlorophenyl)methoxy]-3,4-dihydro-1(2H)-naphthalenone price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AK Scientific 0458DU 7-((2-Bromo-5-chlorobenzyl)oxy)-3,4-dihydronaphthalen-1(2H)-one 1378388-19-2 1g $87 2021-12-16 Buy
AK Scientific 0458DU 7-((2-Bromo-5-chlorobenzyl)oxy)-3,4-dihydronaphthalen-1(2H)-one 1378388-19-2 25g $320 2021-12-16 Buy
Chemenu CM141643 7-((2-bromo-5-chlorobenzyl)oxy)-3,4-dihydronaphthalen-1(2H)-one 97% 1378388-19-2 5g $374 2021-12-16 Buy
Crysdot CD12147467 7-((2-Bromo-5-chlorobenzyl)oxy)-3,4-dihydronaphthalen-1(2H)-one 97% 1378388-19-2 5g $396 2021-12-16 Buy
Ambeed A163700 7-((2-Bromo-5-chlorobenzyl)oxy)-3,4-dihydronaphthalen-1(2H)-one 97% 1378388-19-2 100g $479 2021-12-16 Buy
Product number Packaging Price Buy
0458DU 1g $87 Buy
0458DU 25g $320 Buy
CM141643 5g $374 Buy
CD12147467 5g $396 Buy
A163700 100g $479 Buy

7-[(2-Bromo-5-chlorophenyl)methoxy]-3,4-dihydro-1(2H)-naphthalenone Chemical Properties,Uses,Production

Synthesis

2-Bromo-1-bromomethyl-5-chlorobenzene

66192-24-3

7-Hydroxy-1-tetralone

22009-38-7

7-[(2-Bromo-5-chlorophenyl)methoxy]-3,4-dihydro-1(2H)-naphthalenone

1378388-19-2

The general procedure for the synthesis of 7-[(2-bromo-5-chlorophenyl)methoxy]-3,4-dihydro-1(2H)-naphthalenone from 2-bromo-5-chlorobenzyl bromide and 7-hydroxy-3,4-dihydronaphthalen-1(2H)-one was carried out in the following manner: under argon protection, 7-hydroxy-3,4-dihydronaphthalen-1(2H)-one (13.9 g, 85.7 mmol) and 2-bromo-5- chlorobenzyl bromide (25.6 g, 90.0 mmol) were dissolved in dimethylformamide (850 mL) and potassium carbonate (24 g, 172 mmol) was added. The reaction mixture was stirred at room temperature for 18 hours. After completion of the reaction, the reaction mixture was diluted with ethyl acetate (1 L) and washed sequentially with water three times and brine once. The organic layer was dried with magnesium sulfate, filtered and concentrated. Methanol (500 mL) was added to the oil obtained by concentration and stirred for 30 minutes. The solid product was collected by filtration to afford 7-[(2-bromo-5-chlorophenyl)methoxy]-3,4-dihydro-1(2H)-naphthalenone (27.8 g, 89% yield).

References

[1] Patent: WO2013/75029, 2013, A1. Location in patent: Page/Page column 53-55
[2] Patent: US2013/309196, 2013, A1. Location in patent: Paragraph 0205
[3] Patent: US2014/178336, 2014, A1. Location in patent: Paragraph 0234
[4] Patent: US2015/361073, 2015, A1. Location in patent: Paragraph 0433
[5] Patent: CN107540679, 2018, A. Location in patent: Paragraph 0031; 0032

7-[(2-Bromo-5-chlorophenyl)methoxy]-3,4-dihydro-1(2H)-naphthalenone Preparation Products And Raw materials

Raw materials

2-Bromo-1-bromomethyl-5-chlorobenzene 7-Hydroxy-1-tetralone N,N-Dimethylformamide Potassium carbonate

Preparation Products

7-[(2-Bromo-5-chlorophenyl)methoxy]-3,4-dihydro-1(2H)-naphthalenone Suppliers

Global( 37)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		+86-（0）57185586718; +8613336195806 sales@capot.com China 29735 60
Baoji Guokang Healthchem Co., Ltd. 		+86-0917-3909592 +86-13892490616 gksales1@gk-bio.com China 9209 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418684 +8618949823763 sales@tnjchem.com China 25356 58
GIHI CHEMICALS CO.,LIMITED 		+8618058761490 info@gihichemicals.com China 49936 58
Aladdin Scientific 		tp@aladdinsci.com United States 52923 58
Qingdao Dexin Chemical Co., Ltd 		+86-15553333686 15553333686@qq.com China 3113 58
DAYANG CHEM (HANGZHOU) CO.,LTD 		+86-88938639 +86-17705817739 info@dycnchem.com China 53899 58
Chongqing Chemdad Co., Ltd 		+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39927 58
Acesys Pharmatech 18860950986 tangmanman@zenjipharma.com China 1733 55
Cool Pharm, Ltd 021-60455363 18019463053 sales@coolpharm.com China 12346 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
Baoji Guokang Healthchem Co., Ltd. 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
GIHI CHEMICALS CO.,LIMITED 		58
Aladdin Scientific 		58
Qingdao Dexin Chemical Co., Ltd 		58
DAYANG CHEM (HANGZHOU) CO.,LTD 		58
Chongqing Chemdad Co., Ltd 		58
Acesys Pharmatech 55
Cool Pharm, Ltd 58

View Lastest Price from 7-[(2-Bromo-5-chlorophenyl)methoxy]-3,4-dihydro-1(2H)-naphthalenone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
7-[(2-Bromo-5-chlorophenyl)methoxy]-3,4-dihydro-1(2H)-naphthalenone pictures 2023-06-19 7-[(2-Bromo-5-chlorophenyl)methoxy]-3,4-dihydro-1(2H)-naphthalenone
1378388-19-2
 US $0.00-0.00 / kg 1kg 98% kgs Capot Chemical Co.,Ltd.
7-[(2-Bromo-5-chlorophenyl)methoxy]-3,4-dihydro-1(2H)-naphthalenone pictures 2021-07-13 7-[(2-Bromo-5-chlorophenyl)methoxy]-3,4-dihydro-1(2H)-naphthalenone
1378388-19-2
 US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
7-[(2-Bromo-5-chlorophenyl)methoxy]-3,4-dihydro-1(2H)-naphthalenone pictures 2021-07-10 7-[(2-Bromo-5-chlorophenyl)methoxy]-3,4-dihydro-1(2H)-naphthalenone
1378388-19-2
 US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
7-[(2-Bromo-5-chlorophenyl)methoxy]-3,4-dihydro-1(2H)-naphthalenone 7-((2-Bromo-5-chlorobenzyl)oxy)-3,4-dihydronaphthalen-1(2H)-one CL122 7-(2-bromo-5-chlorobenzyloxy)-3,4-dihydronaphthalene-1(2H)-one 1(2H)-Naphthalenone, 7-[(2-bromo-5-chlorophenyl)methoxy]-3,4-dihydro- 7-(2-bromo-5-chlorobenzyloxy)-1-naphthalenone 1378388-19-2 C17H14BrClO2