PROFOXYDIM-LITHIUM
- CAS No.
- 139001-49-3
- Chemical Name:
- PROFOXYDIM-LITHIUM
- Synonyms
- AIK;AURA;STK7;BTAK;STK6;ARK1;AIRK1;AURKA;STK15;TETRIS
- CBNumber:
- CB4320465
- Molecular Formula:
- C24H32ClNO4S
- Molecular Weight:
- 466.03
- MDL Number:
- MFCD04112607
- MOL File:
- 139001-49-3.mol
| Melting point | <25 °C |
|---|---|
| Boiling point | 597.2±60.0 °C(Predicted) |
| Density | 1.26±0.1 g/cm3(Predicted) |
| storage temp. | -70°C |
| solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
| pka | 4.25±0.25(Predicted) |
| color | White to Off-White |
| Stability | Hygroscopic, Unstable in Solution |
| FDA UNII | T7QYT6EW74 |
| EPA Substance Registry System | Profoxydim (139001-49-3) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07, GHS08 |
|---|---|
| Signal word | Warning |
| Hazard statements | H317-H351-H361d |
| Precautionary statements | P201-P261-P280-P308+P313-P333+P313-P362+P364 |
| Hazard Codes | Xn |
| Risk Statements | 21/22 |
| Safety Statements | 36/37 |
| WGK Germany | 3 |
PROFOXYDIM-LITHIUM price More Price(2)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SRP5034 | GRK2, active, GST tagged human PRECISIO? Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution | 139001-49-3 | 10μG | $520 | 2024-03-01 | Buy |
| American Custom Chemicals Corporation | CHM0290689 | PROFOXYDIM-LITHIUM 98.00% | 139001-49-3 | 1G | $1238.16 | 2021-12-16 | Buy |
PROFOXYDIM-LITHIUM Chemical Properties,Uses,Production
Uses
Profoxydim Lithium Salt is a salt of Profoxydim (139001-49-3) and an herbicide.
Definition
ChEBI: Profoxydim is a cyclic ketone that is 3-hydroxycyclohex-2-en-1-one substituted by a N-[2-(4-chlorophenoxy)propoxy]butanimidoyl group at position 2 and by a thian-3-yl group at position 5. It is a herbicide used for the control of grass weeds in rice. It has a role as a herbicide and an EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor. It is an oxime O-ether, a member of monochlorobenzenes, an aromatic ether, an enol, an organosulfur heterocyclic compound and a cyclic ketone.
General Description
G-protein-coupled receptor kinase 2 (GRK2), which is officially known as adrenergic, beta, receptor kinase 1 (ADRBK1), gene codes for a 689 amino acid protein, that is of 79.573kDa. This gene has 12 catalytic region subdomains. GRK2 is expressed in the vascular endothelium, arterial smooth muscle, myocardium, kidney and in the renal proximal tubule. It is mapped to human chromosome 11q13.
Biochem/physiol Actions
G-protein-coupled receptor kinase 2 (GRK2) or ADRBK1 is a ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G protein-coupled receptors. GRK2 phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. RAF kinase inhibitor protein RKIP is a physiologic inhibitor of GRK2. After stimulation of G protein-coupled receptors, RKIP dissociates from its known target, RAF1 to associate with GRK2 and block its activity. G-protein-coupled receptor kinase 2 (GRK2) controls several intracellular mechanisms. It helps to maintain the structure and activities of the heart. Hence it participates in several cardiovascular diseases. GRK2 also modulates ion and fluid transport and eventually, blood pressure. It increases the synthesis of mitochondrial superoxide and reduces oxygen utilization and ATP synthesis. This protein serves as a major onco-modulator.
PROFOXYDIM-LITHIUM Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10248 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 15319487004 | 1015@dideu.com | China | 2263 | 58 |
| changzhou huayang technology co., ltd | +8615250961469 | 2571773637@qq.com | China | 9821 | 58 |
| Alta Scientific Co., Ltd. | 022-6537-8550 15522853686 | sales@altasci.com.cn | China | 4515 | 55 |
| Shanghai Synchem Pharma Co., ltd | 021-61984905-1 18016477331 | synchempharma@aliyun.com | China | 6454 | 55 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 55717 | 58 |
| Guangdong Wengjiang Chemical Reagent Co., Ltd. | 0751-2886766 13927870850 | 3001267247@qq.com | China | 10067 | 58 |
View Lastest Price from PROFOXYDIM-LITHIUM manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-02-26 | Profoxydim-lithium
139001-49-3
|
US $0.00-0.00 / KG | 1KG | 99.0%+ | 100 tons | Shaanxi Dideu Medichem Co. Ltd | |
 |
2019-07-06 | PROFOXYDIM-LITHIUM
139001-49-3
|
US $1.00 / kg | 1kg | 95%-99% | 10kg | Career Henan Chemical Co |
-
- Profoxydim-lithium
139001-49-3
- US $0.00-0.00 / KG
- 99.0%+
- Shaanxi Dideu Medichem Co. Ltd
-
- PROFOXYDIM-LITHIUM
139001-49-3
- US $1.00 / kg
- 95%-99%
- Career Henan Chemical Co