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simfibrate

simfibrate Structure
simfibrate structure
CAS No.
14929-11-4
Chemical Name:
simfibrate
Synonyms
CLY-503;Sinfibrate;simfibrate;Cholesolvin;simfibrate USP/EP/BP;1,3-Propanediol bis[2-(4-chlorophenoxy)-2-methylpropionate];Propane-1,3-diyl bis(2-(4-chlorophenoxy)-2-methylpropanoate);Bis[2-(4-chlorophenoxy)-2-methylpropanoic acid] 1,3-propanediyl;Propanoic acid, 2-(4-chlorophenoxy)-2-methyl-, 1,1'-(1,3-propanediyl) ester;3-[2-(4-chlorophenoxy)-2-methylpropanoyl]oxypropyl 2-(4-chlorophenoxy)-2-methylpropanoate
CBNumber:
CB4875031
Molecular Formula:
C23H26Cl2O6
Molecular Weight:
469.35
MDL Number:
MFCD00865760
MOL File:
14929-11-4.mol
Last updated:2023-05-04 17:34:33
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simfibrate Properties

Melting point 51-53°
Boiling point bp0.03 197-200°; bp0.15 220-230°
Density 1.2623 (estimate)
FDA UNII L2R75RQX26
ATC code C10AB06

SAFETY

Risk and Safety Statements

Toxicity LD50 in mice, rats (g/kg): 3.3-3.5; 7.3-8.0 orally (Nakanishi, J. Pharm. Soc. Japan)

simfibrate price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation API0004178 SIMFIBRATE 95.00% 14929-11-4 1G $1750 2021-12-16 Buy
American Custom Chemicals Corporation API0004178 SIMFIBRATE 95.00% 14929-11-4 5G $7150 2021-12-16 Buy
Alichem 14929114 Propane-1,3-diylbis(2-(4-chlorophenoxy)-2-methylpropanoate) 14929-11-4 1g $1008 2021-12-16 Buy
Crysdot CD12140008 Propane-1,3-diylbis(2-(4-chlorophenoxy)-2-methylpropanoate) 95+% 14929-11-4 1g $1186 2021-12-16 Buy
Product number Packaging Price Buy
API0004178 1G $1750 Buy
API0004178 5G $7150 Buy
14929114 1g $1008 Buy
CD12140008 1g $1186 Buy

simfibrate Chemical Properties,Uses,Production

Originator

Cholesorbin,Takeda,Japan,1971

Definition

ChEBI: Simfibrate is an organic molecular entity.

Manufacturing Process

A mixture of 22 grams of α-(p-chlorophenoxy)isobutyric acid, 3.8 grams of 1,3-propanediol, 0.5 gram of p-toluenesulfonic acid and 150 ml of xylene was refluxed. When the theoretically calculated amount of water had been removed, the xylene solution was washed with dilute aqueous sodium bicarbonate and then the xylene was distilled off. The residue was distilled under reduced pressure to give 11 grams (47% yield) of 1,3-propanediol bis[α-(p-chlorophenoxy)isobutyrate] boiling at 197° to 200°C/0.03 mm Hg.

Therapeutic Function

Antihyperlipidemic

simfibrate Preparation Products And Raw materials

Raw materials

1,3-Propanediol, 2-(2,2-diethoxyethyl)-,monoacetate,(R)-

Preparation Products

simfibrate Suppliers

Global( 18)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Dideu Medichem Co. Ltd 		+86-029-89586680 +86-18192503167 1026@dideu.com China 9271 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250 1026@dideu.com China 29118 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207 sales@molcore.com China 49739 58
TargetMol Chemicals Inc. 		+1-781-999-5354 support@targetmol.com United States 19973 58
LGM Pharma 1-(800)-881-8210 inquiries@lgmpharma.com United States 2127 70
Aikon International Limited 025-58851090 13611564524 lwan@aikonchem.com China 15952 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24131 58
Shaanxi Dideu Newmaterial Co., Ltd. 029-63373950 15353716720 1052@dideu.com China 10007 58
Supplier Advantage
Shaanxi Dideu Medichem Co. Ltd 		58
Dideu Industries Group Limited 		58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		58
TargetMol Chemicals Inc. 		58
LGM Pharma 70
Aikon International Limited 58
TargetMol Chemicals Inc. 58
Shaanxi Dideu Newmaterial Co., Ltd. 58

View Lastest Price from simfibrate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
simfibrate USP/EP/BP pictures 2021-08-06 simfibrate USP/EP/BP
14929-11-4
 US $1.10 / g 1g 99.9% 100 Tons min Dideu Industries Group Limited

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1of3

simfibrate 1,3-Propanediol bis[2-(4-chlorophenoxy)-2-methylpropionate] Bis[2-(4-chlorophenoxy)-2-methylpropanoic acid] 1,3-propanediyl Cholesolvin CLY-503 Sinfibrate simfibrate USP/EP/BP Propanoic acid, 2-(4-chlorophenoxy)-2-methyl-, 1,1'-(1,3-propanediyl) ester Propane-1,3-diyl bis(2-(4-chlorophenoxy)-2-methylpropanoate) 3-[2-(4-chlorophenoxy)-2-methylpropanoyl]oxypropyl 2-(4-chlorophenoxy)-2-methylpropanoate 14929-11-4 C23H26Cl2O6