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SULPROFOS structure
Chemical Name:
BOLSTAR;ntn9306;Bolster;merpafos;helothion;SULPROFOS;BOLSTAR(R);SULPROPHOS;BAY 123234;mercaprofos
Molecular Formula:
Formula Weight:
MOL File:

SULPROFOS Properties

Melting point:
Boiling point:
bp0.1 155-158°
1.20 g/cm3
vapor pressure 
8.4×10-5Pa (20 °C)
refractive index 
nD20 1.5859
storage temp. 
Water Solubility 
0.31 mg 1l-1(20 °C)
Specific Gravity
1.20 (20℃)
Exposure limits
NIOSH PEL: TWA 1 mg/m3; ACGIH TLV: TWA 1 mg/m3.
EPA Substance Registry System
Sulprofos (35400-43-2)
  • Risk and Safety Statements
Signal word  Danger
Hazard statements  H301+H311-H330-H410
Precautionary statements  P260-P273-P280-P284-P301+P310-P310
Hazard Codes  T,N
Risk Statements  21-23/25-50/53
Safety Statements  36/37-45-60-61
RIDADR  3018
WGK Germany  3
RTECS  TE4165000
HazardClass  6.1(b)
PackingGroup  III
Toxicity LD50 orally in rats: 227 mg/kg (Bull, Ivie)

SULPROFOS price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 45665 Sulprofos PESTANAL 35400-43-2 250mg $44 2021-03-22 Buy

SULPROFOS Chemical Properties,Uses,Production

Chemical Properties

Tan colored liquid; sulfide odor. Soluble in organic solvents; insoluble in water.

Chemical Properties

Sulprofos is a tan colored liquid.




Sulprofos is used to control Lepidoptera, thrips and other insects in cotton, soya, tobacco, vegetables and tomatoes.

General Description

Tan-colored liquid with a sulfide-like odor.

Reactivity Profile

Organothiophosphates are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.


Cholinesterase inhibitor. Questionable carcinogen.

Safety Profile

Poison by ingestion. Moderately toxic by skin contact. When heated to decomposition it emits very toxic fumes of POx and SOx.

Potential Exposure

A potential danger to those involved in the manufacture, formulation, and application of this insecticide that is used for control of certain lepidopterous, dipterous, and hemipterous insects on cotton, etc.

Environmental Fate

Biological. From the first-order biotic and abiotic rate constants of sulprofos in estu- arine water and sediment/water systems, the estimated biodegradation half-lives were 19.5–61.6 and 3.5–19 days, respectively (Walker et al., 1988).
Photolytic. When sulprofos was exposed to sunlight as deposits on cotton foliage, glass surfaces and in aqueous solution, the insecticide degraded rapidly (half-life <2 days). Irradiation of sulprofos in aqueous solution using UV light (λ >290
Chemical/Physical. Emits toxic oxides of sulfur and phosphorus when heated to decomposition (Lewis, 1990).

Metabolic pathway

Sulprofos is an organophosphorus insecticide possessing a 4-(methylthio) phenyl group and as such its metabolic fate has much in common with fenthion with which it also has the phosphorothioate (P=S) group in common. The major route of sulprofos metabolism is by oxidation to the sulfoxide and more slowly to the sulfone. The additional route of bioactivation is through oxidative desulfuration to form the sulprofos oxon and all five oxidative metabolites (sulprofos sulfoxide, sulprofos sulfone, sulprofos oxon, sulprofos oxon sulfoxide and sulprofos oxon sulfone) have been detected in rats. Degradative metabolism by hydrolysis or oxidative dearylation to the phenols occurs rapidly. Stage II metabolism in mammals involves the rapid conjugation of the phenolic dearylation products. The fate of the S-propyl phosphorodithioate group has not apparently been reported.


Major metabolic routes are by oxidation to the sulfoxide and sulfone and oxidative desulfuration to the oxons. Detoxification by dearylation to the phenols occurs rapidly. Sulprofos is degraded in soil with a half-life ranging from a few days to several weeks, depending on the soil type.


UN3018 Organophosphorus pesticides, liquid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.

Toxicity evaluation

The acute oral LD50 for rats is 176–304 mg/kg. Inhalation LC50 (4 h) for rats is >4.1 mg/L air. NOEL (2 yr) for rats is 6 mg/kg diet (0.3 mg/kg/d). ADI is 3 μg/kg b.w. Sulprofos administered to rats is rapidly metabolized, and 92% of the dose is excreted within 24 h.


The half-lives in aqueous solution at pH values 4,7 and 9 were 26,151 and 51 days, respectively. Its DT50 was less than two days when a thin film was exposed to sunlight. Ivie and Bull (1976), examined the photodecomposition in sunlight of sulprofos on cotton leaves, glass surfaces and aqueous solutions. The major metabolites were sulprofos sulfoxide (2) and sulfone (3), with minor amounts of sulprofos oxon sulfoxide (4) and the three possible phenolic hydrolysis products (5, 6 and 7). Photodecomposition is thus via thiooxidation, oxidative desulfuration and cleavage of the P-O-aryl group as shown in Scheme 1. A large number of minor photolysis products which could not be identified were also formed.


Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Strong oxidizers may cause release of toxic phosphorus oxides. Organophosphates, in the presence of strong reducing agents such as hydrides, may form highly toxic and flammable phosphine gas. Keep away from alkaline materials.

Waste Disposal

In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers. Must be disposed properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office.

SULPROFOS Preparation Products And Raw materials

Raw materials

Preparation Products


Global( 65)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Hubei Jusheng Technology Co.,Ltd.
027-59599243 CHINA 28229 58
Hubei xin bonus chemical co. LTD
027-59338440 CHINA 23035 58
career henan chemical co
13203830695 0086-371-86658258
0086-371-86658258 CHINA 29865 58
J & K SCIENTIFIC LTD. 400-666-7788 010-82848833-
86-10-82849933; China 96815 76
BEST-REAGENT 18981987031 400-1166-196;; China 11718 57
Shanghai JONLN Reagent Co., Ltd. 400-0066400
021-55660885; China 9998 55
TianJin Alta Scientific Co., Ltd. +86-022-6537-8550
+86-022-2532-9655 China 2775 58
Alta Scientific Co., Ltd. 022-65378550-
022-2532-9655; China 9070 55
Codow Chemical Co.,Ltd. 18620099427 020-38056109-1040
+86-20-62619665 China 18941 55
Shenzhen Regent Biochemical Technology Co., Ltd. 18938635012 0755-85201366-
0755-85201366; China 9491 58

View Lastest Price from SULPROFOS manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2020-01-13 SULPROFOS
US $1.00 / g 1g 99.0% 100 kg Career Henan Chemical Co

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