ChemicalBook >> CAS DataBase List >>6-hydroxydexamethasone
6-hydroxydexamethasone
- CAS No.
- 55879-47-5
- Chemical Name:
- 6-hydroxydexamethasone
- Synonyms
- 6-hydroxydexamethasone;6β-hydroxy Dexamethasone;Dexamethasone Impurity 12;Dexamethasone 6β-Hydroxy Impurity;Dexamethasone 6beta-Hydroxy Impurity;6-Hydroxydexamethasone Solution, 100ppm;(6R,8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-6,11,17-trihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
- CBNumber:
- CB51341435
- Molecular Formula:
- C22H29FO6
- Molecular Weight:
- 408.46
- MDL Number:
- MOL File:
- 55879-47-5.mol
Last updated:2023-05-18 11:31:20
| Melting point | 259-262°C |
|---|---|
| Boiling point | 613.2±55.0 °C(Predicted) |
| Density | 1.38±0.1 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | Dioxane (Very Slightly, Sonicated), Methanol (Slightly) |
| form | Solid |
| pka | 12.06±0.70(Predicted) |
| color | White to Light Yellow |
| FDA UNII | 017VSH97RJ |
6-hydroxydexamethasone price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 22099 | 6β-hydroxy Dexamethasone ≥98% | 55879-47-5 | 500μg | $214 | 2023-06-20 | Buy |
| Cayman Chemical | 22099 | 6β-hydroxy Dexamethasone ≥98% | 55879-47-5 | 1mg | $405 | 2023-06-20 | Buy |
| TRC | H939500 | 6β-HydroxyDexamethasone | 55879-47-5 | 2.5mg | $215 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | MTB0002203 | 6-BETA-HYDROXY DEXAMETHASONE 95.00% | 55879-47-5 | 5MG | $496.21 | 2021-12-16 | Buy |
| AK Scientific | 3637CA | 6beta-Hydroxydexamethasone | 55879-47-5 | 1mg | $559 | 2021-12-16 | Buy |
6-hydroxydexamethasone Chemical Properties,Uses,Production
Description
6β-hydroxy Dexamethasone is a metabolite of dexamethasone (Item Nos. 11015 | 20340) that is more hydrophilic than the parent compound. Dexamethasone is metabolized by CYP3A4; therefore, quantification of the dexamethasone metabolites, 6α- and 6β-hydroxy dexamethasone, can be used to determine CYP3A4 enzyme activity in humans. The formation of 6-hydroxy dexamethasone metabolites is species-specific, with hamsters producing the highest amount. In rats, dexamethasone hydroxylation is sex-specific, with male rats producing metabolites in similar ratios to humans and female rats producing fewer hydroxylated metabolites than male rats.
Chemical Properties
Off-White Solid
Uses
The hydrophilic metabolite of Dexamethasone (D298800).
6-hydroxydexamethasone Preparation Products And Raw materials
Raw materials
Preparation Products
6-hydroxydexamethasone Suppliers
Global( 28)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14336 | 58 |
| China National Standard Pharmaceutical Corporation Limited | +8615391658522 | overseasales@yongstandards.com | China | 11927 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| S.Z. PhyStandard Bio-Tech. Co., Ltd. | 0755-83725681-603 | China | 4505 | 50 | |
| Clearsynth Labs Limited | +91-22-26355700 | info@clearsynth.com | India | 9685 | 58 |
| Alta Scientific Co., Ltd. | 022-6537-8550 15522853686 | sales@altasci.com.cn | China | 4515 | 55 |
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9926 | 65 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 55827 | 58 |
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6-hydroxydexamethasone
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Dexamethasone Impurity 12
6-Hydroxydexamethasone Solution, 100ppm
(6R,8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-6,11,17-trihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
Dexamethasone 6beta-Hydroxy Impurity
6β-hydroxy Dexamethasone
55879-47-5
C22H29FO6
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Metabolites & Impurities
Pharmaceuticals
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