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12-DEOXYPHORBOL 13-PHENYLACETATE 20-ACETATE

12-DEOXYPHORBOL 13-PHENYLACETATE 20-ACETATE structure

CAS No.: 54662-30-5

Chemical Name:: 12-DEOXYPHORBOL 13-PHENYLACETATE 20-ACETATE

Synonyms: 12-DPPAA;3-acetate9a-phenylacetate;12-deoxyphorbolphenylacetate-20-acetate;12-Deoxyphorbol 13-phenylacate 20-acetate;12-DEOXYPHORBOL 13-PHENYLACETATE 20-ACETATE;(1aR)-3-(Acetyloxymethyl)-1,1aα,1bβ,4,4a,7aα,7b,8,9,9a-decahydro-4aβ,7bα-dihydroxy-1,1,6,8α-tetramethyl-9aα-[(phenylacetyl)oxy]-5H-cyclopropa[3,4]benz[1,2-e]azulen-5-one;Benzeneacetic acid ,(1ar,1bs,4ar,7as,7br,8R,9as)-3-((acetyloxy)methyl)-1,1A,1B,4,4A,5,7A,7B,8,9-decahydro-4A,7B-dihydroxy-1,1,6,8-tetramethyl-5-oxo-9ah-cyclopropa(3,4)benz(1,2-E)azulen-9A-yl ester;5H-Cyclopropa(3,4)benz(1,2-E)azulen-5-one, 1,1A-alpha,1B-beta,4,4A,7A-alpha,7B,8,9,9A-decahydro-4A-beta,7B-alpha,9A-alpha-trihydroxy-3-(hydroxymethyl)-1,1,6,8-alpha-tetramethyl-, 3-acetate 9A-phenylacetate

CBNumber:: CB5171673

Molecular Formula:: C30H36O7

Molecular Weight:: 508.6

MDL Number:: MFCD01741294

MOL File:: 54662-30-5.mol

Last updated:2025-01-27 09:38:02

Product description	Number	Pack Size	Price
dPPA ≥98% (HPLC)	D7821	1mg	$197
12-Deoxyphorbol13-phenylacetate20-acetate	D248503	1mg	$495
12-Deoxyphorbol13-phenylacetate20-acetate	D248503	2.5mg	$855
12-DEOXYPHORBOL 13-PHENYLACETATE 20-ACETATE 95.00%	KIN0000816	5MG	$504.1

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12-DEOXYPHORBOL 13-PHENYLACETATE 20-ACETATE Properties

Boiling point	556.46°C (rough estimate)
Density	1.0979 (rough estimate)
refractive index	1.6810 (estimate)
storage temp.	-20°C
form	oil
color	colorless to light yellow
UNSPSC Code	12352200
NACRES	NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS06
Signal word	Danger
Hazard statements	H300+H310+H330-H315-H319-H335
Precautionary statements	P260-P262-P280-P302+P352+P310-P304+P340+P310-P305+P351+P338
Hazard Codes	T+
Risk Statements	26/27/28-36/37/38
Safety Statements	26-27-36/37/39-45
RIDADR	UN 2811 6.1 / PGIII
WGK Germany	3

12-DEOXYPHORBOL 13-PHENYLACETATE 20-ACETATE price More Price(4)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	D7821	dPPA ≥98% (HPLC)	54662-30-5	1mg	$197	2025-07-31	Buy
TRC	D248503	12-Deoxyphorbol13-phenylacetate20-acetate	54662-30-5	1mg	$495	2021-12-16	Buy
TRC	D248503	12-Deoxyphorbol13-phenylacetate20-acetate	54662-30-5	2.5mg	$855	2021-12-16	Buy
American Custom Chemicals Corporation	KIN0000816	12-DEOXYPHORBOL 13-PHENYLACETATE 20-ACETATE 95.00%	54662-30-5	5MG	$504.1	2021-12-16	Buy

Product number	Packaging	Price	Buy
D7821	1mg	$197	Buy
D248503	1mg	$495	Buy
D248503	2.5mg	$855	Buy
KIN0000816	5MG	$504.1	Buy

12-DEOXYPHORBOL 13-PHENYLACETATE 20-ACETATE Chemical Properties,Uses,Production

Uses

dPPA/phorbol ester 12-deoxyphorbol 13-phenylacetate 20-acetate (DOPPA) may be used as a potent activator of PKC-β:

to tre at transfected HT-22 cells to promote phosphorylation of p66Shc
to tre at HT-22 and B12 cells to study its effects on cell viability
to tre at neurons and measure primary cortical neurons using the 2,5-diphenyl-2H-tetrazolium bromide (MTT) assay

Biological Activity

dPPA is a phorbol ester th at selectively activates the β isotype of PKC. It is approximately 100-fold more potent for PKC-β than the α, γ or δ isotypes. PKC family members each have specific functions, but PKC-β and δ appear to share similar expression profiles, and both are involved in regulating apoptosis and B cell activation, thus dPPA is a useful tool in determining PKCβ specific signaling events.

12-DEOXYPHORBOL 13-PHENYLACETATE 20-ACETATE Preparation Products And Raw materials

Raw materials

Preparation Products

12-DEOXYPHORBOL 13-PHENYLACETATE 20-ACETATE Suppliers

Global( 17)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Aladdin Scientific		tp@aladdinsci.com	United States	52923	58
DAYANG CHEM (HANGZHOU) CO.,LTD	+86-88938639 +86-17705817739	info@dycnchem.com	China	53899	58
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9803	58
Aktin Chemicals, Inc.	028-85159085	info@aktinchem.com	China	1860	58
Energy Chemical	021-58432009 400-005-6266	marketing@energy-chemical.com	China	44918	58
Merck KGaA	21-20338288	ordercn@merckgroup.com	China	6394	58
Santa Cruz Biotechnology Inc	021-60936350	scbt@scbt.com	China	6594	58

Supplier	Advantage
Aladdin Scientific	58
DAYANG CHEM (HANGZHOU) CO.,LTD	58
Shanghai EFE Biological Technology Co., Ltd.	58
Aktin Chemicals, Inc.	58
Energy Chemical	58
Merck KGaA	58
Santa Cruz Biotechnology Inc	58

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BAPTA-AM FTT 12-DEOXYPHORBOL 13-PHENYLACETATE

1of4

12-deoxyphorbolphenylacetate-20-acetate 3-acetate9a-phenylacetate 12-Deoxyphorbol 13-phenylacate 20-acetate 12-DEOXYPHORBOL 13-PHENYLACETATE 20-ACETATE (1aR)-3-(Acetyloxymethyl)-1,1aα,1bβ,4,4a,7aα,7b,8,9,9a-decahydro-4aβ,7bα-dihydroxy-1,1,6,8α-tetramethyl-9aα-[(phenylacetyl)oxy]-5H-cyclopropa[3,4]benz[1,2-e]azulen-5-one 12-DPPAA 5H-Cyclopropa(3,4)benz(1,2-E)azulen-5-one, 1,1A-alpha,1B-beta,4,4A,7A-alpha,7B,8,9,9A-decahydro-4A-beta,7B-alpha,9A-alpha-trihydroxy-3-(hydroxymethyl)-1,1,6,8-alpha-tetramethyl-, 3-acetate 9A-phenylacetate Benzeneacetic acid ,(1ar,1bs,4ar,7as,7br,8R,9as)-3-((acetyloxy)methyl)-1,1A,1B,4,4A,5,7A,7B,8,9-decahydro-4A,7B-dihydroxy-1,1,6,8-tetramethyl-5-oxo-9ah-cyclopropa(3,4)benz(1,2-E)azulen-9A-yl ester 54662-30-5 C30H36O7